| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the amodiaquine-5747 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCB4 | ATP-binding cassette, sub-family B (MDR/TAP), member 4 |
| ABCG2 | ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) |
| AGRP | agouti related neuropeptide |
| AHNAK | AHNAK nucleoprotein |
| ALDOB | aldolase B, fructose-bisphosphate |
| ALOX12 | arachidonate 12-lipoxygenase |
| ANKZF1 | ankyrin repeat and zinc finger domain containing 1 |
| ARHGAP24 | Rho GTPase activating protein 24 |
| ATP10B | ATPase, class V, type 10B |
| BTRC | beta-transducin repeat containing E3 ubiquitin protein ligase |
| C8ORF44 | chromosome 8 open reading frame 44 |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 |
| CAPN9 | calpain 9 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase |
| CCDC85C | coiled-coil domain containing 85C |
| CD34 | CD34 molecule |
| CD79B | CD79b molecule, immunoglobulin-associated beta |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 |
| CLCA1 | chloride channel accessory 1 |
| COL9A3 | collagen, type IX, alpha 3 |
| CREBZF | CREB/ATF bZIP transcription factor |
| CYBA | cytochrome b-245, alpha polypeptide |
| DCHS2 | dachsous cadherin-related 2 |
| DOK1 | docking protein 1, 62kDa (downstream of tyrosine kinase 1) |
| DST | dystonin |
| DUSP7 | dual specificity phosphatase 7 |
| DYNC1LI2 | dynein, cytoplasmic 1, light intermediate chain 2 |
| EDN1 | endothelin 1 |
| ESR1 | estrogen receptor 1 |
| FAM110B | family with sequence similarity 110, member B |
| FOXG1 | forkhead box G1 |
| GAL | galanin/GMAP prepropeptide |
| GALR2 | galanin receptor 2 |
| GLP1R | glucagon-like peptide 1 receptor |
| GP5 | glycoprotein V (platelet) |
| GPR17 | G protein-coupled receptor 17 |
| GRTP1 | growth hormone regulated TBC protein 1 |
| HIST1H4F | histone cluster 1, H4f |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| HNF1B | HNF1 homeobox B |
| HPS1 | Hermansky-Pudlak syndrome 1 |
| HSPG2 | heparan sulfate proteoglycan 2 |
| HTR1B | 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled |
| INSIG1 | insulin induced gene 1 |
| IQSEC2 | IQ motif and Sec7 domain 2 |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 |
| KCNJ5 | potassium channel, inwardly rectifying subfamily J, member 5 |
| KIAA0319L | KIAA0319-like |
| KIAA1456 | KIAA1456 |
| KIR3DX1 | killer cell immunoglobulin-like receptor, three domains, X1 |
| KRT32 | keratin 32, type I |
| LINC00341 | long intergenic non-protein coding RNA 341 |
| LSS | lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) |
| MAP2K5 | mitogen-activated protein kinase kinase 5 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 |
| MS4A1 | membrane-spanning 4-domains, subfamily A, member 1 |
| MTMR8 | myotubularin related protein 8 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) |
| NDUFA5 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 |
| NF1 | neurofibromin 1 |
| NOX1 | NADPH oxidase 1 |
| NRF1 | nuclear respiratory factor 1 |
| NTF3 | neurotrophin 3 |
| ONECUT1 | one cut homeobox 1 |
| OR1G1 | olfactory receptor, family 1, subfamily G, member 1 |
| PAFAH2 | platelet-activating factor acetylhydrolase 2, 40kDa |
| PBX1 | pre-B-cell leukemia homeobox 1 |
| PDE12 | phosphodiesterase 12 |
| PDLIM7 | PDZ and LIM domain 7 (enigma) |
| PHOX2A | paired-like homeobox 2a |
| PKNOX2 | PBX/knotted 1 homeobox 2 |
| PLXNC1 | plexin C1 |
| PMCHL1 | pro-melanin-concentrating hormone-like 1, pseudogene |
| PRKCA | protein kinase C, alpha |
| PRR34 | proline rich 34 |
| PRUNE2 | prune homolog 2 (Drosophila) |
| RAB6B | RAB6B, member RAS oncogene family |
| RBM48 | RNA binding motif protein 48 |
| RUNX1 | runt-related transcription factor 1 |
| SLC2A11 | solute carrier family 2 (facilitated glucose transporter), member 11 |
| SSX1 | synovial sarcoma, X breakpoint 1 |
| SYT17 | synaptotagmin XVII |
| TESPA1 | thymocyte expressed, positive selection associated 1 |
| TFCP2L1 | transcription factor CP2-like 1 |
| TGFA | transforming growth factor, alpha |
| TLX2 | T-cell leukemia homeobox 2 |
| TMEM212 | transmembrane protein 212 |
| TRA | T cell receptor alpha locus |
| TSC2 | tuberous sclerosis 2 |
| WT1-AS | WT1 antisense RNA |
| ZCCHC11 | zinc finger, CCHC domain containing 11 |
| ZCWPW1 | zinc finger, CW type with PWWP domain 1 |
| ZER1 | zyg-11 related, cell cycle regulator |
| ZFX | zinc finger protein, X-linked |
| ZNF44 | zinc finger protein 44 |
| ZNF639 | zinc finger protein 639 |
| Symbol | Name |
|---|---|
| ABHD17B | abhydrolase domain containing 17B |
| ACBD4 | acyl-CoA binding domain containing 4 |
| ACKR3 | atypical chemokine receptor 3 |
| ADAM15 | ADAM metallopeptidase domain 15 |
| ADAP2 | ArfGAP with dual PH domains 2 |
| ADTRP | androgen-dependent TFPI-regulating protein |
| ALPK1 | alpha-kinase 1 |
| ANKRD40 | ankyrin repeat domain 40 |
| ANXA10 | annexin A10 |
| ARHGEF1 | Rho guanine nucleotide exchange factor (GEF) 1 |
| ASIC3 | acid sensing (proton gated) ion channel 3 |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
| C16ORF59 | chromosome 16 open reading frame 59 |
| C1ORF115 | chromosome 1 open reading frame 115 |
| CARD8 | caspase recruitment domain family, member 8 |
| CCRL2 | chemokine (C-C motif) receptor-like 2 |
| CDON | cell adhesion associated, oncogene regulated |
| CGREF1 | cell growth regulator with EF-hand domain 1 |
| CHM | choroideremia (Rab escort protein 1) |
| CHST8 | carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 |
| CLEC2B | C-type lectin domain family 2, member B |
| CLSPN | claspin |
| CNNM4 | cyclin and CBS domain divalent metal cation transport mediator 4 |
| CORT | cortistatin |
| CRY2 | cryptochrome circadian clock 2 |
| CTSF | cathepsin F |
| CXCL3 | chemokine (C-X-C motif) ligand 3 |
| CYP17A1 | cytochrome P450, family 17, subfamily A, polypeptide 1 |
| CYP2B7P | cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene |
| CYP39A1 | cytochrome P450, family 39, subfamily A, polypeptide 1 |
| CYP7B1 | cytochrome P450, family 7, subfamily B, polypeptide 1 |
| DCAF17 | DDB1 and CUL4 associated factor 17 |
| DENND2D | DENN/MADD domain containing 2D |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
| EAF2 | ELL associated factor 2 |
| EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase |
| EHD3 | EH-domain containing 3 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FBXO2 | F-box protein 2 |
| FLJ10038 | uncharacterized protein FLJ10038 |
| FRS3 | fibroblast growth factor receptor substrate 3 |
| FSTL3 | follistatin-like 3 (secreted glycoprotein) |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| HMGB3P1 | high mobility group box 3 pseudogene 1 |
| IFNA14 | interferon, alpha 14 |
| IKZF5 | IKAROS family zinc finger 5 (Pegasus) |
| IL6 | interleukin 6 |
| LPAR3 | lysophosphatidic acid receptor 3 |
| LRFN3 | leucine rich repeat and fibronectin type III domain containing 3 |
| LRP5L | low density lipoprotein receptor-related protein 5-like |
| MAGEB2 | melanoma antigen family B2 |
| MAPK12 | mitogen-activated protein kinase 12 |
| MCTP1 | multiple C2 domains, transmembrane 1 |
| MDFI | MyoD family inhibitor |
| MED15 | mediator complex subunit 15 |
| MOCS3 | molybdenum cofactor synthesis 3 |
| MON1B | MON1 secretory trafficking family member B |
| MUC3A | mucin 3A, cell surface associated |
| MUM1 | melanoma associated antigen (mutated) 1 |
| MVP | major vault protein |
| NME5 | NME/NM23 family member 5 |
| NUP62CL | nucleoporin 62kDa C-terminal like |
| OR12D2 | olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene) |
| PHC1 | polyhomeotic homolog 1 (Drosophila) |
| PID1 | phosphotyrosine interaction domain containing 1 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
| PRR7 | proline rich 7 (synaptic) |
| REPS2 | RALBP1 associated Eps domain containing 2 |
| RNF125 | ring finger protein 125, E3 ubiquitin protein ligase |
| RNF44 | ring finger protein 44 |
| RSAD1 | radical S-adenosyl methionine domain containing 1 |
| SCAMP5 | secretory carrier membrane protein 5 |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit |
| SEC61A2 | Sec61 alpha 2 subunit (S. cerevisiae) |
| SLITRK5 | SLIT and NTRK-like family, member 5 |
| SPATA2L | spermatogenesis associated 2-like |
| SPRYD7 | SPRY domain containing 7 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 |
| STARD3 | StAR-related lipid transfer (START) domain containing 3 |
| STEAP4 | STEAP family member 4 |
| TMC5 | transmembrane channel-like 5 |
| TMEM159 | transmembrane protein 159 |
| TMEM209 | transmembrane protein 209 |
| TRIM45 | tripartite motif containing 45 |
| TTC26 | tetratricopeptide repeat domain 26 |
| UAP1L1 | UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 |
| USP18 | ubiquitin specific peptidase 18 |
| VGF | VGF nerve growth factor inducible |
| VWA1 | von Willebrand factor A domain containing 1 |
| WDR19 | WD repeat domain 19 |
| ZBTB39 | zinc finger and BTB domain containing 39 |
| ZFHX2 | zinc finger homeobox 2 |
| ZFHX3 | zinc finger homeobox 3 |
| ZNF286A | zinc finger protein 286A |
| ZNF32 | zinc finger protein 32 |
| ZNF324 | zinc finger protein 324 |
| ZNF480 | zinc finger protein 480 |
| ZNF671 | zinc finger protein 671 |
| ZNF768 | zinc finger protein 768 |
