amoxapine-2013 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the amoxapine-2013 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACTR3B ARP3 actin-related protein 3 homolog B (yeast)
ACVRL1 activin A receptor type II-like 1
AMT aminomethyltransferase
AP1G2 adaptor-related protein complex 1, gamma 2 subunit
ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
ARHGAP33 Rho GTPase activating protein 33
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ATF6B activating transcription factor 6 beta
ATP7A ATPase, Cu++ transporting, alpha polypeptide
B3GNTL1 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1
BMP15 bone morphogenetic protein 15
C14ORF1 chromosome 14 open reading frame 1
C7ORF43 chromosome 7 open reading frame 43
C9ORF156 chromosome 9 open reading frame 156
CACYBP calcyclin binding protein
CD101 CD101 molecule
CD70 CD70 molecule
CHMP6 charged multivesicular body protein 6
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal)
CLN8 ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
CNTN1 contactin 1
CYFIP2 cytoplasmic FMR1 interacting protein 2
DENND6B DENN/MADD domain containing 6B
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DHX29 DEAH (Asp-Glu-Ala-His) box polypeptide 29
DNAJC16 DnaJ (Hsp40) homolog, subfamily C, member 16
EGR4 early growth response 4
EPS8L1 EPS8-like 1
FAM162A family with sequence similarity 162, member A
FAM188A family with sequence similarity 188, member A
FCGR2C Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
FSCN3 fascin actin-bundling protein 3, testicular
GABPB1 GA binding protein transcription factor, beta subunit 1
GCAT glycine C-acetyltransferase
GK glycerol kinase
GLS glutaminase
GOLGA1 golgin A1
GPR12 G protein-coupled receptor 12
HSD17B3 hydroxysteroid (17-beta) dehydrogenase 3
ICAM2 intercellular adhesion molecule 2
IL2RB interleukin 2 receptor, beta
ITGA10 integrin, alpha 10
KLK1 kallikrein 1
KRT6B keratin 6B, type II
L1TD1 LINE-1 type transposase domain containing 1
LAIR1 leukocyte-associated immunoglobulin-like receptor 1
LPP LIM domain containing preferred translocation partner in lipoma
LTB4R leukotriene B4 receptor
MED7 mediator complex subunit 7
MFSD11 major facilitator superfamily domain containing 11
MKS1 Meckel syndrome, type 1
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MPZL1 myelin protein zero-like 1
MT1E metallothionein 1E
MT1F metallothionein 1F
MT1G metallothionein 1G
MT1H metallothionein 1H
MT1X metallothionein 1X
MT2A metallothionein 2A
MTF1 metal-regulatory transcription factor 1
MYO1C myosin IC
NAT6 N-acetyltransferase 6 (GCN5-related)
NF1 neurofibromin 1
NR2F2 nuclear receptor subfamily 2, group F, member 2
NRSN2 neurensin 2
NUDT2 nudix (nucleoside diphosphate linked moiety X)-type motif 2
OR10H3 olfactory receptor, family 10, subfamily H, member 3
OR1D2 olfactory receptor, family 1, subfamily D, member 2
PEX14 peroxisomal biogenesis factor 14
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PPP1R7 protein phosphatase 1, regulatory subunit 7
PRDM14 PR domain containing 14
PSG3 pregnancy specific beta-1-glycoprotein 3
PTPN12 protein tyrosine phosphatase, non-receptor type 12
RALB v-ral simian leukemia viral oncogene homolog B
RNF19B ring finger protein 19B
RUNDC3A RUN domain containing 3A
SAR1A secretion associated, Ras related GTPase 1A
SFRP4 secreted frizzled-related protein 4
SMAD6 SMAD family member 6
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SOX4 SRY (sex determining region Y)-box 4
SPDEF SAM pointed domain containing ETS transcription factor
ST6GALNAC4 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
TADA2A transcriptional adaptor 2A
TBX10 T-box 10
TCF3 transcription factor 3
TCL1A T-cell leukemia/lymphoma 1A
TFIP11 tuftelin interacting protein 11
TMEM74B transmembrane protein 74B
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TPI1 triosephosphate isomerase 1
TSPAN31 tetraspanin 31
UBOX5 U-box domain containing 5
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae)
WDR48 WD repeat domain 48
ZNF287 zinc finger protein 287
ZNF500 zinc finger protein 500
ZNF787 zinc finger protein 787

decreased expression

Symbol Name
ABCD3 ATP-binding cassette, sub-family D (ALD), member 3
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ALPK1 alpha-kinase 1
ANKRA2 ankyrin repeat, family A (RFXANK-like), 2
ARG1 arginase 1
ARMC7 armadillo repeat containing 7
ASCC1 activating signal cointegrator 1 complex subunit 1
ATAD2B ATPase family, AAA domain containing 2B
ATG2A autophagy related 2A
C1GALT1 core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1
C1ORF54 chromosome 1 open reading frame 54
C6ORF47 chromosome 6 open reading frame 47
C9ORF114 chromosome 9 open reading frame 114
C9ORF40 chromosome 9 open reading frame 40
CCDC6 coiled-coil domain containing 6
CD248 CD248 molecule, endosialin
CD320 CD320 molecule
CEP72 centrosomal protein 72kDa
CHRNA2 cholinergic receptor, nicotinic, alpha 2 (neuronal)
CLDN15 claudin 15
CLDND1 claudin domain containing 1
COPS7B COP9 signalosome subunit 7B
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DEAF1 DEAF1 transcription factor
DEPDC1 DEP domain containing 1
DHRS7B dehydrogenase/reductase (SDR family) member 7B
DOK2 docking protein 2, 56kDa
DPF3 D4, zinc and double PHD fingers, family 3
FAM50A family with sequence similarity 50, member A
FIG4 FIG4 phosphoinositide 5-phosphatase
FKTN fukutin
GRM6 glutamate receptor, metabotropic 6
GRPR gastrin-releasing peptide receptor
HMGB3P1 high mobility group box 3 pseudogene 1
HYAL2 hyaluronoglucosaminidase 2
INO80D INO80 complex subunit D
IRF2BP1 interferon regulatory factor 2 binding protein 1
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KDELC1 KDEL (Lys-Asp-Glu-Leu) containing 1
KIFAP3 kinesin-associated protein 3
KPTN kaptin (actin binding protein)
LINC00339 long intergenic non-protein coding RNA 339
MAPKBP1 mitogen-activated protein kinase binding protein 1
MITF microphthalmia-associated transcription factor
MLYCD malonyl-CoA decarboxylase
MNS1 meiosis-specific nuclear structural 1
MXRA8 matrix-remodelling associated 8
MYO5C myosin VC
NCF1C neutrophil cytosolic factor 1C pseudogene
NDUFB6 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa
NIT1 nitrilase 1
NPLOC4 nuclear protein localization 4 homolog (S. cerevisiae)
NRBP1 nuclear receptor binding protein 1
NSD1 nuclear receptor binding SET domain protein 1
OBFC1 oligonucleotide/oligosaccharide-binding fold containing 1
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1
PAQR3 progestin and adipoQ receptor family member III
PCDHGB5 protocadherin gamma subfamily B, 5
PDXDC1 pyridoxal-dependent decarboxylase domain containing 1
PEMT phosphatidylethanolamine N-methyltransferase
PEX12 peroxisomal biogenesis factor 12
POR P450 (cytochrome) oxidoreductase
PVRL2 poliovirus receptor-related 2 (herpesvirus entry mediator B)
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RGP1 RGP1 retrograde golgi transport homolog (S. cerevisiae)
RNF141 ring finger protein 141
RPAP1 RNA polymerase II associated protein 1
RPUSD2 RNA pseudouridylate synthase domain containing 2
SIRT1 sirtuin 1
SIRT6 sirtuin 6
SLC35A5 solute carrier family 35, member A5
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SNX6 sorting nexin 6
SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
STAG3L1 stromal antigen 3-like 1 (pseudogene)
STXBP2 syntaxin binding protein 2
TARS2 threonyl-tRNA synthetase 2, mitochondrial (putative)
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
THOP1 thimet oligopeptidase 1
TMPRSS6 transmembrane protease, serine 6
TOR4A torsin family 4, member A
TP53BP1 tumor protein p53 binding protein 1
TRIM8 tripartite motif containing 8
TSPAN32 tetraspanin 32
TSSC4 tumor suppressing subtransferable candidate 4
TTC23 tetratricopeptide repeat domain 23
UBE2W ubiquitin-conjugating enzyme E2W (putative)
VPS8 vacuolar protein sorting 8 homolog (S. cerevisiae)
WBP2 WW domain binding protein 2
WDR7 WD repeat domain 7
ZC3H12A zinc finger CCCH-type containing 12A
ZC3H3 zinc finger CCCH-type containing 3
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF282 zinc finger protein 282
ZNF32 zinc finger protein 32
ZNF606 zinc finger protein 606
ZNF671 zinc finger protein 671
ZNF804A zinc finger protein 804A