amoxicillin-2620 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the amoxicillin-2620 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADGRA2 adhesion G protein-coupled receptor A2
ADGRG2 adhesion G protein-coupled receptor G2
AIM1L absent in melanoma 1-like
AP2B1 adaptor-related protein complex 2, beta 1 subunit
ATAD5 ATPase family, AAA domain containing 5
BCL3 B-cell CLL/lymphoma 3
CACFD1 calcium channel flower domain containing 1
CCDC81 coiled-coil domain containing 81
CCR2 chemokine (C-C motif) receptor 2
CFAP69 cilia and flagella associated protein 69
CHRNA2 cholinergic receptor, nicotinic, alpha 2 (neuronal)
CNN1 calponin 1, basic, smooth muscle
COL1A1 collagen, type I, alpha 1
CSF1 colony stimulating factor 1 (macrophage)
CSRP2 cysteine and glycine-rich protein 2
CTNND2 catenin (cadherin-associated protein), delta 2
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
EFS embryonal Fyn-associated substrate
ESR1 estrogen receptor 1
FGB fibrinogen beta chain
FGF6 fibroblast growth factor 6
FGFR2 fibroblast growth factor receptor 2
FLJ21369 uncharacterized protein FLJ21369
FXR2 fragile X mental retardation, autosomal homolog 2
GAS2 growth arrest-specific 2
GFER growth factor, augmenter of liver regeneration
GH1 growth hormone 1
GIMAP5 GTPase, IMAP family member 5
GPR32 G protein-coupled receptor 32
GPX7 glutathione peroxidase 7
HCRP1 hepatocellular carcinoma-related HCRP1
HOXC8 homeobox C8
HPX hemopexin
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IGLL3P immunoglobulin lambda-like polypeptide 3, pseudogene
IL11 interleukin 11
IRAK3 interleukin-1 receptor-associated kinase 3
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
KCNJ1 potassium channel, inwardly rectifying subfamily J, member 1
KCNJ14 potassium channel, inwardly rectifying subfamily J, member 14
KIAA1456 KIAA1456
KLRB1 killer cell lectin-like receptor subfamily B, member 1
LAMB4 laminin, beta 4
LIME1 Lck interacting transmembrane adaptor 1
LOC79999 uncharacterized LOC79999
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MAP1A microtubule-associated protein 1A
MAPRE3 microtubule-associated protein, RP/EB family, member 3
MCOLN1 mucolipin 1
MGAT2 mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
MOCS1 molybdenum cofactor synthesis 1
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTSS1L metastasis suppressor 1-like
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NR2F1 nuclear receptor subfamily 2, group F, member 1
OGFR opioid growth factor receptor
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa
PCDH11Y protocadherin 11 Y-linked
PCDH17 protocadherin 17
PCDHGA3 protocadherin gamma subfamily A, 3
PDLIM3 PDZ and LIM domain 3
PER1 period circadian clock 1
PHLDB1 pleckstrin homology-like domain, family B, member 1
PHTF2 putative homeodomain transcription factor 2
PMFBP1 polyamine modulated factor 1 binding protein 1
PRB3 proline-rich protein BstNI subfamily 3
PRDM12 PR domain containing 12
PROL1 proline rich, lacrimal 1
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1
PTGIS prostaglandin I2 (prostacyclin) synthase
PURG purine-rich element binding protein G
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
RPL35A ribosomal protein L35a
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SEC24D SEC24 family member D
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SOCS3 suppressor of cytokine signaling 3
SOS2 son of sevenless homolog 2 (Drosophila)
ST8SIA3 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
SYMPK symplekin
SYT11 synaptotagmin XI
TAPBPL TAP binding protein-like
TBX5 T-box 5
TBX6 T-box 6
TEF thyrotrophic embryonic factor
TFR2 transferrin receptor 2
TK2 thymidine kinase 2, mitochondrial
TMEM176A transmembrane protein 176A
TMPRSS15 transmembrane protease, serine 15
TNFRSF9 tumor necrosis factor receptor superfamily, member 9
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNXB tenascin XB
TP53I11 tumor protein p53 inducible protein 11
VEGFA vascular endothelial growth factor A
ZCCHC24 zinc finger, CCHC domain containing 24
ZNF528 zinc finger protein 528

decreased expression

Symbol Name
ACSF2 acyl-CoA synthetase family member 2
AEN apoptosis enhancing nuclease
AP3M2 adaptor-related protein complex 3, mu 2 subunit
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
ASTE1 asteroid homolog 1 (Drosophila)
C10ORF2 chromosome 10 open reading frame 2
C10ORF88 chromosome 10 open reading frame 88
C4ORF19 chromosome 4 open reading frame 19
CCND1 cyclin D1
CDC42EP2 CDC42 effector protein (Rho GTPase binding) 2
CENPJ centromere protein J
CENPQ centromere protein Q
CLCN5 chloride channel, voltage-sensitive 5
COA7 cytochrome c oxidase assembly factor 7 (putative)
CWC25 CWC25 spliceosome-associated protein homolog (S. cerevisiae)
CXCL12 chemokine (C-X-C motif) ligand 12
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DCAF16 DDB1 and CUL4 associated factor 16
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
EGR3 early growth response 3
EML4 echinoderm microtubule associated protein like 4
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
ERN2 endoplasmic reticulum to nucleus signaling 2
FHL2 four and a half LIM domains 2
FILIP1L filamin A interacting protein 1-like
FKBP14 FK506 binding protein 14, 22 kDa
FOXC1 forkhead box C1
FZD4 frizzled class receptor 4
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GALT galactose-1-phosphate uridylyltransferase
GAMT guanidinoacetate N-methyltransferase
GATC glutamyl-tRNA(Gln) amidotransferase, subunit C
GINS4 GINS complex subunit 4 (Sld5 homolog)
GLTSCR1 glioma tumor suppressor candidate region gene 1
GMEB1 glucocorticoid modulatory element binding protein 1
H2AFY2 H2A histone family, member Y2
HIRA histone cell cycle regulator
HSPB8 heat shock 22kDa protein 8
IER3 immediate early response 3
KCNK15 potassium channel, two pore domain subfamily K, member 15
LIN7A lin-7 homolog A (C. elegans)
MAGEF1 melanoma antigen family F1
MOCS3 molybdenum cofactor synthesis 3
MPPED2 metallophosphoesterase domain containing 2
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MRPL44 mitochondrial ribosomal protein L44
MSMB microseminoprotein, beta-
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
MYC v-myc avian myelocytomatosis viral oncogene homolog
NIP7 NIP7, nucleolar pre-rRNA processing protein
NME6 NME/NM23 nucleoside diphosphate kinase 6
NPY1R neuropeptide Y receptor Y1
OPN3 opsin 3
ORC2 origin recognition complex, subunit 2
PCOLCE2 procollagen C-endopeptidase enhancer 2
PDIA3 protein disulfide isomerase family A, member 3
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PMM1 phosphomannomutase 1
PRICKLE3 prickle homolog 3 (Drosophila)
PRR3 proline rich 3
RAB11FIP5 RAB11 family interacting protein 5 (class I)
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RBBP8 retinoblastoma binding protein 8
RCL1 RNA terminal phosphate cyclase-like 1
RCOR3 REST corepressor 3
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RPH3AL rabphilin 3A-like (without C2 domains)
SIRAL2 SIR2 antiphage like 2
SLC16A6 solute carrier family 16, member 6
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SNHG3 small nucleolar RNA host gene 3
SOX3 SRY (sex determining region Y)-box 3
SPAG1 sperm associated antigen 1
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1
STC2 stanniocalcin 2
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TMEM104 transmembrane protein 104
TMEM180 transmembrane protein 180
TPST1 tyrosylprotein sulfotransferase 1
TRAPPC13 trafficking protein particle complex 13
TRIM16 tripartite motif containing 16
UBE2W ubiquitin-conjugating enzyme E2W (putative)
UGCG UDP-glucose ceramide glucosyltransferase
URB2 URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
USP18 ubiquitin specific peptidase 18
WDR19 WD repeat domain 19
WDR4 WD repeat domain 4
XYLT2 xylosyltransferase II
ZFP30 ZFP30 zinc finger protein
ZNF239 zinc finger protein 239
ZNF408 zinc finger protein 408
ZNF721 zinc finger protein 721
ZNF74 zinc finger protein 74
ZNF787 zinc finger protein 787
ZSCAN5A zinc finger and SCAN domain containing 5A