amoxicillin-5385 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the amoxicillin-5385 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ADGRF5 adhesion G protein-coupled receptor F5
ADM adrenomedullin
ALDOB aldolase B, fructose-bisphosphate
ALS2CL ALS2 C-terminal like
ARIH2 ariadne RBR E3 ubiquitin protein ligase 2
ARMC4 armadillo repeat containing 4
ARNT aryl hydrocarbon receptor nuclear translocator
ATP11A ATPase, class VI, type 11A
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
BAIAP3 BAI1-associated protein 3
C5AR1 complement component 5a receptor 1
C8ORF60 chromosome 8 open reading frame 60
CD34 CD34 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CEP164 centrosomal protein 164kDa
CLCF1 cardiotrophin-like cytokine factor 1
CLCN7 chloride channel, voltage-sensitive 7
COL14A1 collagen, type XIV, alpha 1
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa
DTNA dystrobrevin, alpha
E2F4 E2F transcription factor 4, p107/p130-binding
EMC3 ER membrane protein complex subunit 3
ERO1LB ERO1-like beta (S. cerevisiae)
FANCA Fanconi anemia, complementation group A
FBXO21 F-box protein 21
FCN2 ficolin (collagen/fibrinogen domain containing lectin) 2
FGF23 fibroblast growth factor 23
FLJ11292
FSTL1 follistatin-like 1
FSTL3 follistatin-like 3 (secreted glycoprotein)
GPC1 glypican 1
GPR137 G protein-coupled receptor 137
GPR157 G protein-coupled receptor 157
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HFE hemochromatosis
HIST1H2BM histone cluster 1, H2bm
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HLA-DRB6 major histocompatibility complex, class II, DR beta 6 (pseudogene)
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
ITGB4 integrin, beta 4
KCNIP1 Kv channel interacting protein 1
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KIF3C kinesin family member 3C
KLF8 Kruppel-like factor 8
KRT17 keratin 17, type I
LEPR leptin receptor
LMOD1 leiomodin 1 (smooth muscle)
MAST3 microtubule associated serine/threonine kinase 3
MC5R melanocortin 5 receptor
MKL1 megakaryoblastic leukemia (translocation) 1
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
NGDN neuroguidin, EIF4E binding protein
NPR3 natriuretic peptide receptor 3
NT5M 5',3'-nucleotidase, mitochondrial
OLFML2B olfactomedin-like 2B
OSBPL3 oxysterol binding protein-like 3
PCLO piccolo presynaptic cytomatrix protein
PDPN podoplanin
PEX3 peroxisomal biogenesis factor 3
PILRA paired immunoglobin-like type 2 receptor alpha
PLCD1 phospholipase C, delta 1
PLEKHS1 pleckstrin homology domain containing, family S member 1
PLK4 polo-like kinase 4
PPP5C protein phosphatase 5, catalytic subunit
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PRPH2 peripherin 2 (retinal degeneration, slow)
PSG9 pregnancy specific beta-1-glycoprotein 9
PTPRJ protein tyrosine phosphatase, receptor type, J
RBFOX2 RNA binding protein, fox-1 homolog (C. elegans) 2
RPL23AP53 ribosomal protein L23a pseudogene 53
RUSC2 RUN and SH3 domain containing 2
S100A8 S100 calcium binding protein A8
SARM1 sterile alpha and TIR motif containing 1
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SGK2 serum/glucocorticoid regulated kinase 2
SH3GL3 SH3-domain GRB2-like 3
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
SLCO1C1 solute carrier organic anion transporter family, member 1C1
SMAD1 SMAD family member 1
SOS2 son of sevenless homolog 2 (Drosophila)
SPRR1B small proline-rich protein 1B
TEF thyrotrophic embryonic factor
TEX15 testis expressed 15
TGFBR1 transforming growth factor, beta receptor 1
TIMP3 TIMP metallopeptidase inhibitor 3
TM4SF1 transmembrane 4 L six family member 1
TMEFF1 transmembrane protein with EGF-like and two follistatin-like domains 1
TMOD1 tropomodulin 1
TREX1 three prime repair exonuclease 1
VPS53 vacuolar protein sorting 53 homolog (S. cerevisiae)
WIPF1 WAS/WASL interacting protein family, member 1
WSCD1 WSC domain containing 1
ZFP64 ZFP64 zinc finger protein

decreased expression

Symbol Name
ADGRG2 adhesion G protein-coupled receptor G2
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ALPK1 alpha-kinase 1
APLP1 amyloid beta (A4) precursor-like protein 1
BAHD1 bromo adjacent homology domain containing 1
BBC3 BCL2 binding component 3
C11ORF30 chromosome 11 open reading frame 30
C5ORF45 chromosome 5 open reading frame 45
CA5BP1 carbonic anhydrase VB pseudogene 1
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CD79B CD79b molecule, immunoglobulin-associated beta
CENPQ centromere protein Q
CLCN6 chloride channel, voltage-sensitive 6
CLIC2 chloride intracellular channel 2
COPZ2 coatomer protein complex, subunit zeta 2
CTC1 CTS telomere maintenance complex component 1
CTSF cathepsin F
CUZD1 CUB and zona pellucida-like domains 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DEAF1 DEAF1 transcription factor
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
DZANK1 double zinc ribbon and ankyrin repeat domains 1
EFNA3 ephrin-A3
EGFL7 EGF-like-domain, multiple 7
EPHX2 epoxide hydrolase 2, cytoplasmic
ERN2 endoplasmic reticulum to nucleus signaling 2
ETAA1 Ewing tumor-associated antigen 1
ETNK2 ethanolamine kinase 2
EXD3 exonuclease 3'-5' domain containing 3
FAM120C family with sequence similarity 120C
FAM212B family with sequence similarity 212, member B
FAM46C family with sequence similarity 46, member C
FBXL2 F-box and leucine-rich repeat protein 2
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FKBP5 FK506 binding protein 5
GJA9 gap junction protein, alpha 9, 59kDa
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HCFC2 host cell factor C2
HIRA histone cell cycle regulator
HIST1H1D histone cluster 1, H1d
HIST1H3B histone cluster 1, H3b
HOXC5 homeobox C5
HOXD11 homeobox D11
IFI27 interferon, alpha-inducible protein 27
IFT81 intraflagellar transport 81
IGSF1 immunoglobulin superfamily, member 1
INPP5J inositol polyphosphate-5-phosphatase J
IQCG IQ motif containing G
KCNK12 potassium channel, two pore domain subfamily K, member 12
KIFC1 kinesin family member C1
LMCD1 LIM and cysteine-rich domains 1
LMNB1 lamin B1
LPXN leupaxin
METTL22 methyltransferase like 22
MMP9 matrix metallopeptidase 9
NACA2 nascent polypeptide-associated complex alpha subunit 2
NAT9 N-acetyltransferase 9 (GCN5-related, putative)
NPM3 nucleophosmin/nucleoplasmin 3
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
PAIP2B poly(A) binding protein interacting protein 2B
PARD6A par-6 family cell polarity regulator alpha
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
PLXNA3 plexin A3
PODXL2 podocalyxin-like 2
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein
RBM41 RNA binding motif protein 41
RHOBTB1 Rho-related BTB domain containing 1
RPAP2 RNA polymerase II associated protein 2
RPH3AL rabphilin 3A-like (without C2 domains)
RPL23AP32 ribosomal protein L23a pseudogene 32
SAYSD1 SAYSVFN motif domain containing 1
SIK1 salt-inducible kinase 1
SLC12A9 solute carrier family 12, member 9
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLC44A1 solute carrier family 44 (choline transporter), member 1
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1
SP1 Sp1 transcription factor
ST5 suppression of tumorigenicity 5
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TMEM212 transmembrane protein 212
TMUB2 transmembrane and ubiquitin-like domain containing 2
TNS2 tensin 2
UBQLN4 ubiquilin 4
USP20 ubiquitin specific peptidase 20
VLDLR very low density lipoprotein receptor
YEATS2 YEATS domain containing 2
ZBED1 zinc finger, BED-type containing 1
ZBTB22 zinc finger and BTB domain containing 22
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF254 zinc finger protein 254
ZNF350 zinc finger protein 350
ZNF551 zinc finger protein 551
ZNF639 zinc finger protein 639