amoxicillin-6285 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the amoxicillin-6285 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ABI2 abl-interactor 2
AMDHD2 amidohydrolase domain containing 2
ANKRD1 ankyrin repeat domain 1 (cardiac muscle)
ASPHD1 aspartate beta-hydroxylase domain containing 1
ATP10B ATPase, class V, type 10B
BDKRB2 bradykinin receptor B2
BRF2 BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit
C19ORF40 chromosome 19 open reading frame 40
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2
CALD1 caldesmon 1
CCR2 chemokine (C-C motif) receptor 2
CD52 CD52 molecule
CDC25A cell division cycle 25A
CDH3 cadherin 3, type 1, P-cadherin (placental)
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CEP162 centrosomal protein 162kDa
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal)
CIB2 calcium and integrin binding family member 2
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
COBLL1 cordon-bleu WH2 repeat protein-like 1
COL9A3 collagen, type IX, alpha 3
COQ7 coenzyme Q7 homolog, ubiquinone (yeast)
CPT1A carnitine palmitoyltransferase 1A (liver)
CRMP1 collapsin response mediator protein 1
CROCC ciliary rootlet coiled-coil, rootletin
CST4 cystatin S
CTNND2 catenin (cadherin-associated protein), delta 2
CTNS cystinosin, lysosomal cystine transporter
CTRC chymotrypsin C (caldecrin)
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
DSCAM Down syndrome cell adhesion molecule
DTX2P1-UPK3BP1-PMS2P11 DTX2P1-UPK3BP1-PMS2P11 readthrough transcribed pseudogene
DVL2 dishevelled segment polarity protein 2
EFR3B EFR3 homolog B (S. cerevisiae)
ELAVL3 ELAV like neuron-specific RNA binding protein 3
FLJ21369 uncharacterized protein FLJ21369
FXR2 fragile X mental retardation, autosomal homolog 2
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
HFE hemochromatosis
IMPG2 interphotoreceptor matrix proteoglycan 2
INADL InaD-like (Drosophila)
KRT6B keratin 6B, type II
LAMA4 laminin, alpha 4
LEF1 lymphoid enhancer-binding factor 1
LLPH LLP homolog, long-term synaptic facilitation (Aplysia)
LMF1 lipase maturation factor 1
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
MKL1 megakaryoblastic leukemia (translocation) 1
MTA1 metastasis associated 1
MX1 MX dynamin-like GTPase 1
MYH14 myosin, heavy chain 14, non-muscle
NAALAD2 N-acetylated alpha-linked acidic dipeptidase 2
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NOVA1 neuro-oncological ventral antigen 1
NPEPL1 aminopeptidase-like 1
OR2H2 olfactory receptor, family 2, subfamily H, member 2
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa
PCDH12 protocadherin 12
PHLDB1 pleckstrin homology-like domain, family B, member 1
PLXND1 plexin D1
PRSS8 protease, serine, 8
PTPRE protein tyrosine phosphatase, receptor type, E
RAB27B RAB27B, member RAS oncogene family
RAD54L2 RAD54-like 2 (S. cerevisiae)
RECQL5 RecQ protein-like 5
ROR1 receptor tyrosine kinase-like orphan receptor 1
RPLP2 ribosomal protein, large, P2
RRAGB Ras-related GTP binding B
RUSC2 RUN and SH3 domain containing 2
SAMD9 sterile alpha motif domain containing 9
SCN3B sodium channel, voltage gated, type III beta subunit
SHMT1 serine hydroxymethyltransferase 1 (soluble)
SIRAL2 SIR2 antiphage like 2
SLC10A1 solute carrier family 10 (sodium/bile acid cotransporter), member 1
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SLC37A1 solute carrier family 37 (glucose-6-phosphate transporter), member 1
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SNX13 sorting nexin 13
SPSB3 splA/ryanodine receptor domain and SOCS box containing 3
SPTBN1 spectrin, beta, non-erythrocytic 1
SRPX2 sushi-repeat containing protein, X-linked 2
SSH3 slingshot protein phosphatase 3
ST3GAL6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6
SUN2 Sad1 and UNC84 domain containing 2
TBC1D17 TBC1 domain family, member 17
TBX5 T-box 5
TK2 thymidine kinase 2, mitochondrial
TMEM63A transmembrane protein 63A
TMEM8B transmembrane protein 8B
TRD T cell receptor delta locus
TUBA3C tubulin, alpha 3c
WIPF1 WAS/WASL interacting protein family, member 1
WWOX WW domain containing oxidoreductase
ZBTB14 zinc finger and BTB domain containing 14
ZMAT5 zinc finger, matrin-type 5
ZNF688 zinc finger protein 688

decreased expression

Symbol Name
AATF apoptosis antagonizing transcription factor
ALDOC aldolase C, fructose-bisphosphate
ANXA2P3 annexin A2 pseudogene 3
AP1G2 adaptor-related protein complex 1, gamma 2 subunit
ARRB2 arrestin, beta 2
ATF7IP2 activating transcription factor 7 interacting protein 2
BDH1 3-hydroxybutyrate dehydrogenase, type 1
BGLAP bone gamma-carboxyglutamate (gla) protein
BIK BCL2-interacting killer (apoptosis-inducing)
BOLA1 bolA family member 1
BSPRY B-box and SPRY domain containing
C11ORF80 chromosome 11 open reading frame 80
CADPS2 Ca++-dependent secretion activator 2
CCDC130 coiled-coil domain containing 130
CCDC94 coiled-coil domain containing 94
CCS copper chaperone for superoxide dismutase
CHKB choline kinase beta
CINP cyclin-dependent kinase 2 interacting protein
COG7 component of oligomeric golgi complex 7
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DHRS7B dehydrogenase/reductase (SDR family) member 7B
DOLK dolichol kinase
DYNC1I1 dynein, cytoplasmic 1, intermediate chain 1
ELP3 elongator acetyltransferase complex subunit 3
ENO2 enolase 2 (gamma, neuronal)
ERN2 endoplasmic reticulum to nucleus signaling 2
EVPL envoplakin
EXOSC5 exosome component 5
F3 coagulation factor III (thromboplastin, tissue factor)
FADS2 fatty acid desaturase 2
FANCF Fanconi anemia, complementation group F
FBXL4 F-box and leucine-rich repeat protein 4
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GAL3ST4 galactose-3-O-sulfotransferase 4
GRAMD4 GRAM domain containing 4
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
HDAC5 histone deacetylase 5
HIST1H1E histone cluster 1, H1e
HIST1H2AJ histone cluster 1, H2aj
HIST1H2AM histone cluster 1, H2am
HIST1H3G histone cluster 1, H3g
IFNAR1 interferon (alpha, beta and omega) receptor 1
IL17RA interleukin 17 receptor A
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1
KDM4D lysine (K)-specific demethylase 4D
LNPEP leucyl/cystinyl aminopeptidase
LYRM2 LYR motif containing 2
MANEA mannosidase, endo-alpha
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MAPK3 mitogen-activated protein kinase 3
MFSD10 major facilitator superfamily domain containing 10
MLF2 myeloid leukemia factor 2
MOXD1 monooxygenase, DBH-like 1
MYO19 myosin XIX
MYO1D myosin ID
NARFL nuclear prelamin A recognition factor-like
NOTCH1 notch 1
NPM3 nucleophosmin/nucleoplasmin 3
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PALMD palmdelphin
PC pyruvate carboxylase
PECR peroxisomal trans-2-enoyl-CoA reductase
PHGDH phosphoglycerate dehydrogenase
POLD4 polymerase (DNA-directed), delta 4, accessory subunit
PRR7 proline rich 7 (synaptic)
QTRT1 queuine tRNA-ribosyltransferase 1
RANBP17 RAN binding protein 17
RGS17 regulator of G-protein signaling 17
SCG5 secretogranin V
SCRN3 secernin 3
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
SH3BGR SH3 domain binding glutamate-rich protein
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
SLITRK5 SLIT and NTRK-like family, member 5
SPATA2L spermatogenesis associated 2-like
ST5 suppression of tumorigenicity 5
STBD1 starch binding domain 1
SYTL2 synaptotagmin-like 2
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
TAOK1 TAO kinase 1
TCF7L1 transcription factor 7-like 1 (T-cell specific, HMG-box)
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TMEM110 transmembrane protein 110
TMEM132A transmembrane protein 132A
TMEM183A transmembrane protein 183A
TRIM45 tripartite motif containing 45
TUBA3D tubulin, alpha 3d
UBAC1 UBA domain containing 1
VASP vasodilator-stimulated phosphoprotein
ZKSCAN4 zinc finger with KRAB and SCAN domains 4
ZNF212 zinc finger protein 212
ZNF304 zinc finger protein 304
ZNF385D zinc finger protein 385D
ZNF767P zinc finger family member 767, pseudogene
ZSCAN5A zinc finger and SCAN domain containing 5A