| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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196 genes differentially expressed following the amoxicillin-6285 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCA7 | ATP-binding cassette, sub-family A (ABC1), member 7 |
| ABI2 | abl-interactor 2 |
| AMDHD2 | amidohydrolase domain containing 2 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) |
| ASPHD1 | aspartate beta-hydroxylase domain containing 1 |
| ATP10B | ATPase, class V, type 10B |
| BDKRB2 | bradykinin receptor B2 |
| BRF2 | BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit |
| C19ORF40 | chromosome 19 open reading frame 40 |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 |
| CALD1 | caldesmon 1 |
| CCR2 | chemokine (C-C motif) receptor 2 |
| CD52 | CD52 molecule |
| CDC25A | cell division cycle 25A |
| CDH3 | cadherin 3, type 1, P-cadherin (placental) |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 |
| CEP162 | centrosomal protein 162kDa |
| CHRNA6 | cholinergic receptor, nicotinic, alpha 6 (neuronal) |
| CIB2 | calcium and integrin binding family member 2 |
| CLUHP3 | clustered mitochondria (cluA/CLU1) homolog pseudogene 3 |
| COBLL1 | cordon-bleu WH2 repeat protein-like 1 |
| COL9A3 | collagen, type IX, alpha 3 |
| COQ7 | coenzyme Q7 homolog, ubiquinone (yeast) |
| CPT1A | carnitine palmitoyltransferase 1A (liver) |
| CRMP1 | collapsin response mediator protein 1 |
| CROCC | ciliary rootlet coiled-coil, rootletin |
| CST4 | cystatin S |
| CTNND2 | catenin (cadherin-associated protein), delta 2 |
| CTNS | cystinosin, lysosomal cystine transporter |
| CTRC | chymotrypsin C (caldecrin) |
| CYP4F11 | cytochrome P450, family 4, subfamily F, polypeptide 11 |
| DNAJB12 | DnaJ (Hsp40) homolog, subfamily B, member 12 |
| DSCAM | Down syndrome cell adhesion molecule |
| DTX2P1-UPK3BP1-PMS2P11 | DTX2P1-UPK3BP1-PMS2P11 readthrough transcribed pseudogene |
| DVL2 | dishevelled segment polarity protein 2 |
| EFR3B | EFR3 homolog B (S. cerevisiae) |
| ELAVL3 | ELAV like neuron-specific RNA binding protein 3 |
| FLJ21369 | uncharacterized protein FLJ21369 |
| FXR2 | fragile X mental retardation, autosomal homolog 2 |
| GNL3LP1 | guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1 |
| HFE | hemochromatosis |
| IMPG2 | interphotoreceptor matrix proteoglycan 2 |
| INADL | InaD-like (Drosophila) |
| KRT6B | keratin 6B, type II |
| LAMA4 | laminin, alpha 4 |
| LEF1 | lymphoid enhancer-binding factor 1 |
| LLPH | LLP homolog, long-term synaptic facilitation (Aplysia) |
| LMF1 | lipase maturation factor 1 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 |
| MKL1 | megakaryoblastic leukemia (translocation) 1 |
| MTA1 | metastasis associated 1 |
| MX1 | MX dynamin-like GTPase 1 |
| MYH14 | myosin, heavy chain 14, non-muscle |
| NAALAD2 | N-acetylated alpha-linked acidic dipeptidase 2 |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
| NOVA1 | neuro-oncological ventral antigen 1 |
| NPEPL1 | aminopeptidase-like 1 |
| OR2H2 | olfactory receptor, family 2, subfamily H, member 2 |
| PAFAH2 | platelet-activating factor acetylhydrolase 2, 40kDa |
| PCDH12 | protocadherin 12 |
| PHLDB1 | pleckstrin homology-like domain, family B, member 1 |
| PLXND1 | plexin D1 |
| PRSS8 | protease, serine, 8 |
| PTPRE | protein tyrosine phosphatase, receptor type, E |
| RAB27B | RAB27B, member RAS oncogene family |
| RAD54L2 | RAD54-like 2 (S. cerevisiae) |
| RECQL5 | RecQ protein-like 5 |
| ROR1 | receptor tyrosine kinase-like orphan receptor 1 |
| RPLP2 | ribosomal protein, large, P2 |
| RRAGB | Ras-related GTP binding B |
| RUSC2 | RUN and SH3 domain containing 2 |
| SAMD9 | sterile alpha motif domain containing 9 |
| SCN3B | sodium channel, voltage gated, type III beta subunit |
| SHMT1 | serine hydroxymethyltransferase 1 (soluble) |
| SIRAL2 | SIR2 antiphage like 2 |
| SLC10A1 | solute carrier family 10 (sodium/bile acid cotransporter), member 1 |
| SLC24A1 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 |
| SLC37A1 | solute carrier family 37 (glucose-6-phosphate transporter), member 1 |
| SLC7A9 | solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) |
| SNX13 | sorting nexin 13 |
| SPSB3 | splA/ryanodine receptor domain and SOCS box containing 3 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 |
| SRPX2 | sushi-repeat containing protein, X-linked 2 |
| SSH3 | slingshot protein phosphatase 3 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 |
| SUN2 | Sad1 and UNC84 domain containing 2 |
| TBC1D17 | TBC1 domain family, member 17 |
| TBX5 | T-box 5 |
| TK2 | thymidine kinase 2, mitochondrial |
| TMEM63A | transmembrane protein 63A |
| TMEM8B | transmembrane protein 8B |
| TRD | T cell receptor delta locus |
| TUBA3C | tubulin, alpha 3c |
| WIPF1 | WAS/WASL interacting protein family, member 1 |
| WWOX | WW domain containing oxidoreductase |
| ZBTB14 | zinc finger and BTB domain containing 14 |
| ZMAT5 | zinc finger, matrin-type 5 |
| ZNF688 | zinc finger protein 688 |
| Symbol | Name |
|---|---|
| AATF | apoptosis antagonizing transcription factor |
| ALDOC | aldolase C, fructose-bisphosphate |
| ANXA2P3 | annexin A2 pseudogene 3 |
| AP1G2 | adaptor-related protein complex 1, gamma 2 subunit |
| ARRB2 | arrestin, beta 2 |
| ATF7IP2 | activating transcription factor 7 interacting protein 2 |
| BDH1 | 3-hydroxybutyrate dehydrogenase, type 1 |
| BGLAP | bone gamma-carboxyglutamate (gla) protein |
| BIK | BCL2-interacting killer (apoptosis-inducing) |
| BOLA1 | bolA family member 1 |
| BSPRY | B-box and SPRY domain containing |
| C11ORF80 | chromosome 11 open reading frame 80 |
| CADPS2 | Ca++-dependent secretion activator 2 |
| CCDC130 | coiled-coil domain containing 130 |
| CCDC94 | coiled-coil domain containing 94 |
| CCS | copper chaperone for superoxide dismutase |
| CHKB | choline kinase beta |
| CINP | cyclin-dependent kinase 2 interacting protein |
| COG7 | component of oligomeric golgi complex 7 |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides |
| DDX6 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 |
| DHRS7B | dehydrogenase/reductase (SDR family) member 7B |
| DOLK | dolichol kinase |
| DYNC1I1 | dynein, cytoplasmic 1, intermediate chain 1 |
| ELP3 | elongator acetyltransferase complex subunit 3 |
| ENO2 | enolase 2 (gamma, neuronal) |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| EVPL | envoplakin |
| EXOSC5 | exosome component 5 |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| FADS2 | fatty acid desaturase 2 |
| FANCF | Fanconi anemia, complementation group F |
| FBXL4 | F-box and leucine-rich repeat protein 4 |
| GABPA | GA binding protein transcription factor, alpha subunit 60kDa |
| GAL3ST4 | galactose-3-O-sulfotransferase 4 |
| GRAMD4 | GRAM domain containing 4 |
| GUCY1A3 | guanylate cyclase 1, soluble, alpha 3 |
| HDAC5 | histone deacetylase 5 |
| HIST1H1E | histone cluster 1, H1e |
| HIST1H2AJ | histone cluster 1, H2aj |
| HIST1H2AM | histone cluster 1, H2am |
| HIST1H3G | histone cluster 1, H3g |
| IFNAR1 | interferon (alpha, beta and omega) receptor 1 |
| IL17RA | interleukin 17 receptor A |
| IMPDH1 | IMP (inosine 5'-monophosphate) dehydrogenase 1 |
| KDM4D | lysine (K)-specific demethylase 4D |
| LNPEP | leucyl/cystinyl aminopeptidase |
| LYRM2 | LYR motif containing 2 |
| MANEA | mannosidase, endo-alpha |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 |
| MAPK3 | mitogen-activated protein kinase 3 |
| MFSD10 | major facilitator superfamily domain containing 10 |
| MLF2 | myeloid leukemia factor 2 |
| MOXD1 | monooxygenase, DBH-like 1 |
| MYO19 | myosin XIX |
| MYO1D | myosin ID |
| NARFL | nuclear prelamin A recognition factor-like |
| NOTCH1 | notch 1 |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| PALMD | palmdelphin |
| PC | pyruvate carboxylase |
| PECR | peroxisomal trans-2-enoyl-CoA reductase |
| PHGDH | phosphoglycerate dehydrogenase |
| POLD4 | polymerase (DNA-directed), delta 4, accessory subunit |
| PRR7 | proline rich 7 (synaptic) |
| QTRT1 | queuine tRNA-ribosyltransferase 1 |
| RANBP17 | RAN binding protein 17 |
| RGS17 | regulator of G-protein signaling 17 |
| SCG5 | secretogranin V |
| SCRN3 | secernin 3 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A |
| SH3BGR | SH3 domain binding glutamate-rich protein |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 |
| SLITRK5 | SLIT and NTRK-like family, member 5 |
| SPATA2L | spermatogenesis associated 2-like |
| ST5 | suppression of tumorigenicity 5 |
| STBD1 | starch binding domain 1 |
| SYTL2 | synaptotagmin-like 2 |
| TAF13 | TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa |
| TAOK1 | TAO kinase 1 |
| TCF7L1 | transcription factor 7-like 1 (T-cell specific, HMG-box) |
| TINF2 | TERF1 (TRF1)-interacting nuclear factor 2 |
| TMEM110 | transmembrane protein 110 |
| TMEM132A | transmembrane protein 132A |
| TMEM183A | transmembrane protein 183A |
| TRIM45 | tripartite motif containing 45 |
| TUBA3D | tubulin, alpha 3d |
| UBAC1 | UBA domain containing 1 |
| VASP | vasodilator-stimulated phosphoprotein |
| ZKSCAN4 | zinc finger with KRAB and SCAN domains 4 |
| ZNF212 | zinc finger protein 212 |
| ZNF304 | zinc finger protein 304 |
| ZNF385D | zinc finger protein 385D |
| ZNF767P | zinc finger family member 767, pseudogene |
| ZSCAN5A | zinc finger and SCAN domain containing 5A |