ampicillin-1530 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the ampicillin-1530 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ABHD6 abhydrolase domain containing 6
AKAP7 A kinase (PRKA) anchor protein 7
ANP32A-IT1 ANP32A intronic transcript 1
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
APC adenomatous polyposis coli
APOC1 apolipoprotein C-I
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28
ARTN artemin
ATAT1 alpha tubulin acetyltransferase 1
ATN1 atrophin 1
C21ORF2 chromosome 21 open reading frame 2
CASP9 caspase 9, apoptosis-related cysteine peptidase
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CEP152 centrosomal protein 152kDa
CIDEB cell death-inducing DFFA-like effector b
COL19A1 collagen, type XIX, alpha 1
DDX51 DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5
DOCK5 dedicator of cytokinesis 5
DTX2 deltex 2, E3 ubiquitin ligase
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EDRF1 erythroid differentiation regulatory factor 1
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3
FGF13 fibroblast growth factor 13
FLOT1 flotillin 1
FSCN1 fascin actin-bundling protein 1
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2
GPR143 G protein-coupled receptor 143
GPR27 G protein-coupled receptor 27
HCFC1R1 host cell factor C1 regulator 1 (XPO1 dependent)
HIST1H1B histone cluster 1, H1b
HOXC8 homeobox C8
HYAL1 hyaluronoglucosaminidase 1
IFIT5 interferon-induced protein with tetratricopeptide repeats 5
IL22 interleukin 22
JUN jun proto-oncogene
KANSL1L KAT8 regulatory NSL complex subunit 1-like
LOC644450 uncharacterized LOC644450
LPXN leupaxin
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
MAPK13 mitogen-activated protein kinase 13
MARK2 MAP/microtubule affinity-regulating kinase 2
MARK4 MAP/microtubule affinity-regulating kinase 4
MED18 mediator complex subunit 18
MLXIP MLX interacting protein
MST1 macrophage stimulating 1
MTA1 metastasis associated 1
NCALD neurocalcin delta
NLGN1 neuroligin 1
NNAT neuronatin
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
PCSK6 proprotein convertase subtilisin/kexin type 6
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PDK3 pyruvate dehydrogenase kinase, isozyme 3
PGLYRP1 peptidoglycan recognition protein 1
PMS2P2 postmeiotic segregation increased 2 pseudogene 2
POMT2 protein-O-mannosyltransferase 2
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PRELP proline/arginine-rich end leucine-rich repeat protein
PRLR prolactin receptor
PTK6 protein tyrosine kinase 6
PTPN2 protein tyrosine phosphatase, non-receptor type 2
PTPRF protein tyrosine phosphatase, receptor type, F
RNF122 ring finger protein 122
RNF126P1 ring finger protein 126 pseudogene 1
RTN2 reticulon 2
SFRP4 secreted frizzled-related protein 4
SIK2 salt-inducible kinase 2
SIRT5 sirtuin 5
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC44A1 solute carrier family 44 (choline transporter), member 1
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
SPG20 spastic paraplegia 20 (Troyer syndrome)
SRPR signal recognition particle receptor (docking protein)
SYNJ2 synaptojanin 2
TAOK1 TAO kinase 1
TMEM45A transmembrane protein 45A
TOR4A torsin family 4, member A
TP53I11 tumor protein p53 inducible protein 11
TPR translocated promoter region, nuclear basket protein
TRABD TraB domain containing
TRPM8 transient receptor potential cation channel, subfamily M, member 8
TUBA3C tubulin, alpha 3c
TUBA4B tubulin, alpha 4b
USP48 ubiquitin specific peptidase 48
VAC14 Vac14 homolog (S. cerevisiae)
VEZT vezatin, adherens junctions transmembrane protein
WNK1 WNK lysine deficient protein kinase 1
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6
ZCCHC24 zinc finger, CCHC domain containing 24
ZNF365 zinc finger protein 365
ZNF639 zinc finger protein 639
ZSCAN2 zinc finger and SCAN domain containing 2

decreased expression

Symbol Name
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ADRBK2 adrenergic, beta, receptor kinase 2
ARHGAP10 Rho GTPase activating protein 10
ARL15 ADP-ribosylation factor-like 15
ASB9 ankyrin repeat and SOCS box containing 9
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
BAX BCL2-associated X protein
BCL2L2 BCL2-like 2
C22ORF29 chromosome 22 open reading frame 29
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CENPC centromere protein C
CEP97 centrosomal protein 97kDa
CGA glycoprotein hormones, alpha polypeptide
CGREF1 cell growth regulator with EF-hand domain 1
CHKB choline kinase beta
CIC capicua transcriptional repressor
CLCN6 chloride channel, voltage-sensitive 6
CNR2 cannabinoid receptor 2 (macrophage)
CORO7 coronin 7
CTSF cathepsin F
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DLST dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
FBXO31 F-box protein 31
FMOD fibromodulin
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GMPR guanosine monophosphate reductase
GRTP1 growth hormone regulated TBC protein 1
HIST1H4D histone cluster 1, H4d
IKZF5 IKAROS family zinc finger 5 (Pegasus)
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
JUNB jun B proto-oncogene
KAT2A K(lysine) acetyltransferase 2A
KLHL25 kelch-like family member 25
KRT13 keratin 13, type I
LGALS4 lectin, galactoside-binding, soluble, 4
LMNB1 lamin B1
LONRF3 LON peptidase N-terminal domain and ring finger 3
LY6D lymphocyte antigen 6 complex, locus D
MAGEF1 melanoma antigen family F1
MCOLN3 mucolipin 3
MMP2 matrix metallopeptidase 2
MRPL52 mitochondrial ribosomal protein L52
MT1E metallothionein 1E
MYL5 myosin, light chain 5, regulatory
MYLIP myosin regulatory light chain interacting protein
NPFFR1 neuropeptide FF receptor 1
NPTX1 neuronal pentraxin I
NT5DC3 5'-nucleotidase domain containing 3
ODF2 outer dense fiber of sperm tails 2
PLEKHG6 pleckstrin homology domain containing, family G (with RhoGef domain) member 6
POLH polymerase (DNA directed), eta
PRRG2 proline rich Gla (G-carboxyglutamic acid) 2
RASAL1 RAS protein activator like 1 (GAP1 like)
RFTN1 raftlin, lipid raft linker 1
RGS19 regulator of G-protein signaling 19
RIN2 Ras and Rab interactor 2
RNF121 ring finger protein 121
ROM1 retinal outer segment membrane protein 1
RPL13P5 ribosomal protein L13 pseudogene 5
SCN1B sodium channel, voltage gated, type I beta subunit
SLC35F5 solute carrier family 35, member F5
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SLIT2 slit homolog 2 (Drosophila)
SLMO1 slowmo homolog 1 (Drosophila)
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SMCO4 single-pass membrane protein with coiled-coil domains 4
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SUN2 Sad1 and UNC84 domain containing 2
TBX19 T-box 19
TEX40 testis expressed 40
TFF2 trefoil factor 2
TICAM1 toll-like receptor adaptor molecule 1
TLR5 toll-like receptor 5
TMC5 transmembrane channel-like 5
TMCC2 transmembrane and coiled-coil domain family 2
TMEM121 transmembrane protein 121
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
UBE2L6 ubiquitin-conjugating enzyme E2L 6
UBTD1 ubiquitin domain containing 1
UNC93B1 unc-93 homolog B1 (C. elegans)
UPP1 uridine phosphorylase 1
VEGFB vascular endothelial growth factor B
VPS9D1 VPS9 domain containing 1
WDR91 WD repeat domain 91
WNT10B wingless-type MMTV integration site family, member 10B
YIF1B Yip1 interacting factor homolog B (S. cerevisiae)
ZNF394 zinc finger protein 394
ZNF484 zinc finger protein 484
ZNF516 zinc finger protein 516
ZNF580 zinc finger protein 580
ZNF747 zinc finger protein 747