ampicillin-6307 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

194 genes differentially expressed following the ampicillin-6307 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACSL5 acyl-CoA synthetase long-chain family member 5
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
AHSP alpha hemoglobin stabilizing protein
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
AP4E1 adaptor-related protein complex 4, epsilon 1 subunit
APAF1 apoptotic peptidase activating factor 1
ARHGAP33 Rho GTPase activating protein 33
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ARMCX2 armadillo repeat containing, X-linked 2
ARTN artemin
ASPHD1 aspartate beta-hydroxylase domain containing 1
ATG10 autophagy related 10
B3GNTL1 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1
BAX BCL2-associated X protein
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
CACNA2D1 calcium channel, voltage-dependent, alpha 2/delta subunit 1
CALCR calcitonin receptor
CALD1 caldesmon 1
CCDC186 coiled-coil domain containing 186
CCDC88A coiled-coil domain containing 88A
CD58 CD58 molecule
CFLAR CASP8 and FADD-like apoptosis regulator
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
COL7A1 collagen, type VII, alpha 1
CRMP1 collapsin response mediator protein 1
CST1 cystatin SN
CYP4A11 cytochrome P450, family 4, subfamily A, polypeptide 11
DNAL4 dynein, axonemal, light chain 4
DPY19L1P1 DPY19L1 pseudogene 1
DRD2 dopamine receptor D2
DSTYK dual serine/threonine and tyrosine protein kinase
EED embryonic ectoderm development
EFNA3 ephrin-A3
EGFR epidermal growth factor receptor
ETNK2 ethanolamine kinase 2
FOXG1 forkhead box G1
FRS3 fibroblast growth factor receptor substrate 3
FXYD2 FXYD domain containing ion transport regulator 2
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GPLD1 glycosylphosphatidylinositol specific phospholipase D1
GPR17 G protein-coupled receptor 17
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HOXB2 homeobox B2
IDS iduronate 2-sulfatase
IGL immunoglobulin lambda locus
IL1R1 interleukin 1 receptor, type I
IRAK4 interleukin-1 receptor-associated kinase 4
ITGB4 integrin, beta 4
KAZALD1 Kazal-type serine peptidase inhibitor domain 1
KCTD13 potassium channel tetramerization domain containing 13
KIAA1109 KIAA1109
KRT8P12 keratin 8 pseudogene 12
LDAH lipid droplet associated hydrolase
LEF1 lymphoid enhancer-binding factor 1
LIN7B lin-7 homolog B (C. elegans)
LMTK1 lemur tail kinase 1
LOC81691 exonuclease NEF-sp
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A
MUL1 mitochondrial E3 ubiquitin protein ligase 1
N4BP1 NEDD4 binding protein 1
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2)
NF2 neurofibromin 2 (merlin)
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
OBSL1 obscurin-like 1
OLFML2B olfactomedin-like 2B
OR12D2 olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene)
OVGP1 oviductal glycoprotein 1, 120kDa
PICALM phosphatidylinositol binding clathrin assembly protein
PLAG1 pleiomorphic adenoma gene 1
PLCH1 phospholipase C, eta 1
PLIN2 perilipin 2
PPARD peroxisome proliferator-activated receptor delta
PRR4 proline rich 4 (lacrimal)
PTK7 protein tyrosine kinase 7 (inactive)
RAB31 RAB31, member RAS oncogene family
RALGDS ral guanine nucleotide dissociation stimulator
RANGAP1 Ran GTPase activating protein 1
RIBC2 RIB43A domain with coiled-coils 2
RIMS2 regulating synaptic membrane exocytosis 2
RPRM reprimo, TP53 dependent G2 arrest mediator candidate
SCN8A sodium channel, voltage gated, type VIII alpha subunit
SH2D3A SH2 domain containing 3A
SIX2 SIX homeobox 2
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2
SSH3 slingshot protein phosphatase 3
SSX3 synovial sarcoma, X breakpoint 3
ST6GALNAC4 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
TBX5 T-box 5
TMSB15A thymosin beta 15a
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
VWA5A von Willebrand factor A domain containing 5A
ZFP30 ZFP30 zinc finger protein

decreased expression

Symbol Name
ACIN1 apoptotic chromatin condensation inducer 1
ANOS1 anosmin 1
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ARRB2 arrestin, beta 2
ATAD5 ATPase family, AAA domain containing 5
BEX1 brain expressed, X-linked 1
BGLAP bone gamma-carboxyglutamate (gla) protein
BIK BCL2-interacting killer (apoptosis-inducing)
C11ORF30 chromosome 11 open reading frame 30
C1RL complement component 1, r subcomponent-like
CALCOCO1 calcium binding and coiled-coil domain 1
CBR4 carbonyl reductase 4
CCDC85C coiled-coil domain containing 85C
CCDC94 coiled-coil domain containing 94
CCNJ cyclin J
CDADC1 cytidine and dCMP deaminase domain containing 1
CDKN2AIP CDKN2A interacting protein
CEP97 centrosomal protein 97kDa
COG4 component of oligomeric golgi complex 4
CXORF56 chromosome X open reading frame 56
DENND4A DENN/MADD domain containing 4A
DHX38 DEAH (Asp-Glu-Ala-His) box polypeptide 38
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
EHD3 EH-domain containing 3
FBXO46 F-box protein 46
FLCN folliculin
FURIN furin (paired basic amino acid cleaving enzyme)
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GAL3ST4 galactose-3-O-sulfotransferase 4
GAREM GRB2 associated, regulator of MAPK1
GLCE glucuronic acid epimerase
GMIP GEM interacting protein
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GPR3 G protein-coupled receptor 3
HOXA2 homeobox A2
IFT54 intraflagellar transport 54
IL1RAP interleukin 1 receptor accessory protein
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase
KIAA0513 KIAA0513
KIAA1462 KIAA1462
KLHL12 kelch-like family member 12
LHX6 LIM homeobox 6
LNPEP leucyl/cystinyl aminopeptidase
LOC100286895 cell division cycle 27 homolog pseudogene
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LSR lipolysis stimulated lipoprotein receptor
LYPD1 LY6/PLAUR domain containing 1
MCRS1 microspherule protein 1
MED15 mediator complex subunit 15
MFSD12 major facilitator superfamily domain containing 12
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MUC7 mucin 7, secreted
MYL5 myosin, light chain 5, regulatory
NARFL nuclear prelamin A recognition factor-like
NLRX1 NLR family member X1
NUDT13 nudix (nucleoside diphosphate linked moiety X)-type motif 13
PALMD palmdelphin
PC pyruvate carboxylase
PCSK7 proprotein convertase subtilisin/kexin type 7
PLCD1 phospholipase C, delta 1
POLA2 polymerase (DNA directed), alpha 2, accessory subunit
PPL periplakin
PPP6R3 protein phosphatase 6, regulatory subunit 3
RAB8B RAB8B, member RAS oncogene family
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RNF31 ring finger protein 31
SCRN3 secernin 3
SETMAR SET domain and mariner transposase fusion gene
SIX1 SIX homeobox 1
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10
SYNPO synaptopodin
SYTL2 synaptotagmin-like 2
TCTN1 tectonic family member 1
TDRD7 tudor domain containing 7
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TMEM104 transmembrane protein 104
TMEM156 transmembrane protein 156
TMEM159 transmembrane protein 159
TMEM242 transmembrane protein 242
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12
TNRC6B trinucleotide repeat containing 6B
TPRA1 transmembrane protein, adipocyte asscociated 1
TRIM16 tripartite motif containing 16
TUBA3C tubulin, alpha 3c
UNC119 unc-119 homolog (C. elegans)
USB1 U6 snRNA biogenesis 1
WASF1 WAS protein family, member 1
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZC3H12A zinc finger CCCH-type containing 12A
ZNF177 zinc finger protein 177
ZNF214 zinc finger protein 214
ZNF253 zinc finger protein 253
ZNF254 zinc finger protein 254
ZNF430 zinc finger protein 430
ZNF442 zinc finger protein 442
ZNF84 zinc finger protein 84