amprolium-1898 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

200 genes differentially expressed following the amprolium-1898 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACTC1 actin, alpha, cardiac muscle 1
AGFG2 ArfGAP with FG repeats 2
AHI1 Abelson helper integration site 1
ANXA2P3 annexin A2 pseudogene 3
ART1 ADP-ribosyltransferase 1
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ATP11B ATPase, class VI, type 11B
ATXN2 ataxin 2
BBIP1 BBSome interacting protein 1
BCLAF1 BCL2-associated transcription factor 1
BMPR1A bone morphogenetic protein receptor, type IA
C18ORF25 chromosome 18 open reading frame 25
C1ORF109 chromosome 1 open reading frame 109
CCNT2 cyclin T2
CIAO1 cytosolic iron-sulfur assembly component 1
CLCC1 chloride channel CLIC-like 1
CLCN3 chloride channel, voltage-sensitive 3
CLN8 ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
COL5A3 collagen, type V, alpha 3
CPOX coproporphyrinogen oxidase
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DHRS2 dehydrogenase/reductase (SDR family) member 2
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
DOPEY1 dopey family member 1
EGR1 early growth response 1
F11R F11 receptor
FAM188A family with sequence similarity 188, member A
FAM63A family with sequence similarity 63, member A
FDX1 ferredoxin 1
GJD2 gap junction protein, delta 2, 36kDa
GOSR2 golgi SNAP receptor complex member 2
GPR107 G protein-coupled receptor 107
GRK5 G protein-coupled receptor kinase 5
GRM6 glutamate receptor, metabotropic 6
GYPB glycophorin B (MNS blood group)
HFE hemochromatosis
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IL11 interleukin 11
IL6ST interleukin 6 signal transducer
IQCE IQ motif containing E
KLF12 Kruppel-like factor 12
KLHL20 kelch-like family member 20
KLHL21 kelch-like family member 21
KLHL3 kelch-like family member 3
MAP7D3 MAP7 domain containing 3
MARCKS myristoylated alanine-rich protein kinase C substrate
MBD3 methyl-CpG binding domain protein 3
MED13L mediator complex subunit 13-like
MPPE1 metallophosphoesterase 1
MTF2 metal response element binding transcription factor 2
NCS1 neuronal calcium sensor 1
NEK11 NIMA-related kinase 11
NET1 neuroepithelial cell transforming 1
NIPAL2 NIPA-like domain containing 2
NUDT11 nudix (nucleoside diphosphate linked moiety X)-type motif 11
NUDT2 nudix (nucleoside diphosphate linked moiety X)-type motif 2
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
PPDPF pancreatic progenitor cell differentiation and proliferation factor
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H
PPP2R3A protein phosphatase 2, regulatory subunit B'', alpha
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTP4A1 protein tyrosine phosphatase type IVA, member 1
RGS19 regulator of G-protein signaling 19
RIPK2 receptor-interacting serine-threonine kinase 2
RPL23AP7 ribosomal protein L23a pseudogene 7
RPL7 ribosomal protein L7
SAP18 Sin3A-associated protein, 18kDa
SBNO1 strawberry notch homolog 1 (Drosophila)
SEC23B Sec23 homolog B (S. cerevisiae)
SLC17A9 solute carrier family 17 (vesicular nucleotide transporter), member 9
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
SLC22A14 solute carrier family 22, member 14
SOAT1 sterol O-acyltransferase 1
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
STAM2 signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
TAF12 TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa
TAOK1 TAO kinase 1
TCEB1 transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)
TCP11L1 t-complex 11, testis-specific-like 1
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TGFBI transforming growth factor, beta-induced, 68kDa
THBS3 thrombospondin 3
TNS1 tensin 1
TPT1 tumor protein, translationally-controlled 1
TRAF4 TNF receptor-associated factor 4
TRAFD1 TRAF-type zinc finger domain containing 1
TUBA4B tubulin, alpha 4b
UBA5 ubiquitin-like modifier activating enzyme 5
UBE3A ubiquitin protein ligase E3A
UBXN2B UBX domain protein 2B
ULK2 unc-51 like autophagy activating kinase 2
UPK1B uroplakin 1B
USF2 upstream transcription factor 2, c-fos interacting
VIPR1 vasoactive intestinal peptide receptor 1
YRDC yrdC N(6)-threonylcarbamoyltransferase domain containing
ZNF124 zinc finger protein 124
ZNF652 zinc finger protein 652
ZNHIT2 zinc finger, HIT-type containing 2

decreased expression

Symbol Name
ANKRD11 ankyrin repeat domain 11
APOO apolipoprotein O
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28
ASL argininosuccinate lyase
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
BMS1 BMS1 ribosome biogenesis factor
C2ORF44 chromosome 2 open reading frame 44
CASC3 cancer susceptibility candidate 3
CDC45 cell division cycle 45
CLK3 CDC-like kinase 3
COQ9 coenzyme Q9
CRIP2 cysteine-rich protein 2
DEAF1 DEAF1 transcription factor
EMG1 EMG1 N1-specific pseudouridine methyltransferase
ENTPD3 ectonucleoside triphosphate diphosphohydrolase 3
ESM1 endothelial cell-specific molecule 1
ETNK2 ethanolamine kinase 2
EVPL envoplakin
FAM102A family with sequence similarity 102, member A
FCGRT Fc fragment of IgG, receptor, transporter, alpha
GMPPA GDP-mannose pyrophosphorylase A
GNL3 guanine nucleotide binding protein-like 3 (nucleolar)
GP1BA glycoprotein Ib (platelet), alpha polypeptide
GRM4 glutamate receptor, metabotropic 4
GSTZ1 glutathione S-transferase zeta 1
H2BFS H2B histone family, member S (pseudogene)
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HIST1H2BI histone cluster 1, H2bi
HIST3H2A histone cluster 3, H2a
HLA-DMB major histocompatibility complex, class II, DM beta
HMBOX1 homeobox containing 1
INO80D INO80 complex subunit D
INTS9 integrator complex subunit 9
KRT75 keratin 75, type II
LAS1L LAS1-like (S. cerevisiae)
LRPAP1 low density lipoprotein receptor-related protein associated protein 1
MANSC1 MANSC domain containing 1
MAP1S microtubule-associated protein 1S
MAP3K6 mitogen-activated protein kinase kinase kinase 6
MED9 mediator complex subunit 9
METTL22 methyltransferase like 22
MGAT4B mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B
MKLN1 muskelin 1, intracellular mediator containing kelch motifs
MLST8 MTOR associated protein, LST8 homolog (S. cerevisiae)
MPHOSPH8 M-phase phosphoprotein 8
MVP major vault protein
NAV2 neuron navigator 2
NFS1 NFS1 cysteine desulfurase
NMNAT2 nicotinamide nucleotide adenylyltransferase 2
NRD1 nardilysin (N-arginine dibasic convertase)
NRGN neurogranin (protein kinase C substrate, RC3)
NRSN2 neurensin 2
OGFRL1 opioid growth factor receptor-like 1
OSGEP O-sialoglycoprotein endopeptidase
PADI1 peptidyl arginine deiminase, type I
PAF1 Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
PCTP phosphatidylcholine transfer protein
PEPD peptidase D
PHKA1 phosphorylase kinase, alpha 1 (muscle)
PLCD1 phospholipase C, delta 1
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
POGLUT1 protein O-glucosyltransferase 1
POLD1 polymerase (DNA directed), delta 1, catalytic subunit
POTEKP POTE ankyrin domain family, member K, pseudogene
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme
PRKCD protein kinase C, delta
PRKRIP1 PRKR interacting protein 1 (IL11 inducible)
PRRG2 proline rich Gla (G-carboxyglutamic acid) 2
PUS1 pseudouridylate synthase 1
RBM10 RNA binding motif protein 10
RBMS3 RNA binding motif, single stranded interacting protein 3
RECQL4 RecQ protein-like 4
RIC8A RIC8 guanine nucleotide exchange factor A
RIN1 Ras and Rab interactor 1
RPL23AP32 ribosomal protein L23a pseudogene 32
SEZ6L2 seizure related 6 homolog (mouse)-like 2
SLC19A2 solute carrier family 19 (thiamine transporter), member 2
SLC25A1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
SLC35C2 solute carrier family 35 (GDP-fucose transporter), member C2
SLC39A7 solute carrier family 39 (zinc transporter), member 7
SLC4A2 solute carrier family 4 (anion exchanger), member 2
SSNA1 Sjogren syndrome nuclear autoantigen 1
STK25 serine/threonine kinase 25
SURF2 surfeit 2
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3
TEFM transcription elongation factor, mitochondrial
TIMM10B translocase of inner mitochondrial membrane 10 homolog B (yeast)
TMEM62 transmembrane protein 62
TRPM2 transient receptor potential cation channel, subfamily M, member 2
TSG101 tumor susceptibility 101
TSR2 TSR2, 20S rRNA accumulation, homolog (S. cerevisiae)
TTC4 tetratricopeptide repeat domain 4
ULK1 unc-51 like autophagy activating kinase 1
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
VAT1 vesicle amine transport 1
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
WNT16 wingless-type MMTV integration site family, member 16
ZFHX4 zinc finger homeobox 4
ZNF35 zinc finger protein 35
ZNHIT1 zinc finger, HIT-type containing 1