| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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198 genes differentially expressed following the amprolium-4825 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ALDH1L1 | aldehyde dehydrogenase 1 family, member L1 |
| ANGPTL2 | angiopoietin-like 2 |
| AP4E1 | adaptor-related protein complex 4, epsilon 1 subunit |
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 |
| ARMC4 | armadillo repeat containing 4 |
| ATP6V0A2 | ATPase, H+ transporting, lysosomal V0 subunit a2 |
| BAIAP3 | BAI1-associated protein 3 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A |
| BRF1 | BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit |
| CAMK2B | calcium/calmodulin-dependent protein kinase II beta |
| CAMSAP1 | calmodulin regulated spectrin-associated protein 1 |
| CARF | calcium responsive transcription factor |
| CD47 | CD47 molecule |
| CDC42 | cell division cycle 42 |
| CHD5 | chromodomain helicase DNA binding protein 5 |
| COL1A1 | collagen, type I, alpha 1 |
| CR1 | complement component (3b/4b) receptor 1 (Knops blood group) |
| CTNS | cystinosin, lysosomal cystine transporter |
| DCTN1 | dynactin 1 |
| DLEU2 | deleted in lymphocytic leukemia 2 (non-protein coding) |
| DUSP6 | dual specificity phosphatase 6 |
| EFNB3 | ephrin-B3 |
| EPHB1 | EPH receptor B1 |
| ERAP1 | endoplasmic reticulum aminopeptidase 1 |
| FGF18 | fibroblast growth factor 18 |
| FMO5 | flavin containing monooxygenase 5 |
| FOXG1 | forkhead box G1 |
| FSCN3 | fascin actin-bundling protein 3, testicular |
| GABBR2 | gamma-aminobutyric acid (GABA) B receptor, 2 |
| GJB3 | gap junction protein, beta 3, 31kDa |
| GNA14 | guanine nucleotide binding protein (G protein), alpha 14 |
| GP2 | glycoprotein 2 (zymogen granule membrane) |
| GPR173 | G protein-coupled receptor 173 |
| HCRP1 | hepatocellular carcinoma-related HCRP1 |
| HIST1H4E | histone cluster 1, H4e |
| HLA-DMB | major histocompatibility complex, class II, DM beta |
| HOXB6 | homeobox B6 |
| HR | hair growth associated |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 |
| ICA1 | islet cell autoantigen 1, 69kDa |
| IFNA14 | interferon, alpha 14 |
| IGFBP5 | insulin-like growth factor binding protein 5 |
| IL11 | interleukin 11 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) |
| KCNH2 | potassium channel, voltage gated eag related subfamily H, member 2 |
| KLHL20 | kelch-like family member 20 |
| MFSD11 | major facilitator superfamily domain containing 11 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase |
| MID1 | midline 1 |
| MMP25 | matrix metallopeptidase 25 |
| MTHFR | methylenetetrahydrofolate reductase (NAD(P)H) |
| NDST1 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 |
| NR2E3 | nuclear receptor subfamily 2, group E, member 3 |
| NT5M | 5',3'-nucleotidase, mitochondrial |
| NUDT11 | nudix (nucleoside diphosphate linked moiety X)-type motif 11 |
| NXPE3 | neurexophilin and PC-esterase domain family, member 3 |
| OR1D2 | olfactory receptor, family 1, subfamily D, member 2 |
| OSGIN2 | oxidative stress induced growth inhibitor family member 2 |
| PCLO | piccolo presynaptic cytomatrix protein |
| PHC3 | polyhomeotic homolog 3 (Drosophila) |
| PIK3IP1 | phosphoinositide-3-kinase interacting protein 1 |
| PLAU | plasminogen activator, urokinase |
| PMCHL1 | pro-melanin-concentrating hormone-like 1, pseudogene |
| PMFBP1 | polyamine modulated factor 1 binding protein 1 |
| PML | promyelocytic leukemia |
| PMS2P2 | postmeiotic segregation increased 2 pseudogene 2 |
| POLR2J4 | polymerase (RNA) II (DNA directed) polypeptide J4, pseudogene |
| PPP1R14D | protein phosphatase 1, regulatory (inhibitor) subunit 14D |
| PRDM2 | PR domain containing 2, with ZNF domain |
| PTCRA | pre T-cell antigen receptor alpha |
| PTPRD | protein tyrosine phosphatase, receptor type, D |
| RAB6B | RAB6B, member RAS oncogene family |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 |
| RUNX1 | runt-related transcription factor 1 |
| RUSC2 | RUN and SH3 domain containing 2 |
| SIGLEC8 | sialic acid binding Ig-like lectin 8 |
| SLC12A4 | solute carrier family 12 (potassium/chloride transporter), member 4 |
| SLC7A10 | solute carrier family 7 (neutral amino acid transporter light chain, asc system), member 10 |
| SMAD3 | SMAD family member 3 |
| SOS2 | son of sevenless homolog 2 (Drosophila) |
| TAOK2 | TAO kinase 2 |
| TEF | thyrotrophic embryonic factor |
| TLE4 | transducin-like enhancer of split 4 |
| TMPRSS2 | transmembrane protease, serine 2 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b |
| TNFRSF9 | tumor necrosis factor receptor superfamily, member 9 |
| TPMT | thiopurine S-methyltransferase |
| TRIM36 | tripartite motif containing 36 |
| TSC22D2 | TSC22 domain family, member 2 |
| TTLL3 | tubulin tyrosine ligase-like family member 3 |
| USP22 | ubiquitin specific peptidase 22 |
| UTRN | utrophin |
| ZFHX2 | zinc finger homeobox 2 |
| ZFP30 | ZFP30 zinc finger protein |
| ZFX | zinc finger protein, X-linked |
| ZNF480 | zinc finger protein 480 |
| ZNF609 | zinc finger protein 609 |
| Symbol | Name |
|---|---|
| ADCY6 | adenylate cyclase 6 |
| ALKBH4 | alkB, alkylation repair homolog 4 (E. coli) |
| AP1B1 | adaptor-related protein complex 1, beta 1 subunit |
| ARL15 | ADP-ribosylation factor-like 15 |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
| C1ORF159 | chromosome 1 open reading frame 159 |
| CA11 | carbonic anhydrase XI |
| CAPG | capping protein (actin filament), gelsolin-like |
| CHPF | chondroitin polymerizing factor |
| CKB | creatine kinase, brain |
| CLDN15 | claudin 15 |
| CNN2 | calponin 2 |
| CORO7 | coronin 7 |
| CSTA | cystatin A (stefin A) |
| CTDP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 |
| DEAF1 | DEAF1 transcription factor |
| DGCR11 | DiGeorge syndrome critical region gene 11 (non-protein coding) |
| DHX57 | DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 |
| DNAJC17 | DnaJ (Hsp40) homolog, subfamily C, member 17 |
| DSCAM | Down syndrome cell adhesion molecule |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| ERO1L | ERO1-like (S. cerevisiae) |
| FAM189A2 | family with sequence similarity 189, member A2 |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| GCHFR | GTP cyclohydrolase I feedback regulator |
| GEMIN8 | gem (nuclear organelle) associated protein 8 |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| GPX2 | glutathione peroxidase 2 |
| HLA-DRB1 | major histocompatibility complex, class II, DR beta 1 |
| HMOX1 | heme oxygenase 1 |
| HSD17B1 | hydroxysteroid (17-beta) dehydrogenase 1 |
| INO80D | INO80 complex subunit D |
| KDM5C | lysine (K)-specific demethylase 5C |
| KRT8P12 | keratin 8 pseudogene 12 |
| LAMA3 | laminin, alpha 3 |
| LARP6 | La ribonucleoprotein domain family, member 6 |
| LSM7 | LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae) |
| MANBA | mannosidase, beta A, lysosomal |
| MED15 | mediator complex subunit 15 |
| MEFV | Mediterranean fever |
| MITF | microphthalmia-associated transcription factor |
| MKS1 | Meckel syndrome, type 1 |
| MOGS | mannosyl-oligosaccharide glucosidase |
| MOSPD3 | motile sperm domain containing 3 |
| MPP3 | membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
| MTHFSD | methenyltetrahydrofolate synthetase domain containing |
| MTMR12 | myotubularin related protein 12 |
| MUM1 | melanoma associated antigen (mutated) 1 |
| MYO1D | myosin ID |
| NKAIN1 | Na+/K+ transporting ATPase interacting 1 |
| NOL12 | nucleolar protein 12 |
| NRSN2 | neurensin 2 |
| NT5C | 5', 3'-nucleotidase, cytosolic |
| NTHL1 | nth endonuclease III-like 1 (E. coli) |
| NUDT2 | nudix (nucleoside diphosphate linked moiety X)-type motif 2 |
| ODF2 | outer dense fiber of sperm tails 2 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 |
| PANK4 | pantothenate kinase 4 |
| PCDHB3 | protocadherin beta 3 |
| PCYT2 | phosphate cytidylyltransferase 2, ethanolamine |
| PIGQ | phosphatidylinositol glycan anchor biosynthesis, class Q |
| POLD2 | polymerase (DNA directed), delta 2, accessory subunit |
| PRSS16 | protease, serine, 16 (thymus) |
| PTPRU | protein tyrosine phosphatase, receptor type, U |
| RPAP1 | RNA polymerase II associated protein 1 |
| RPL10L | ribosomal protein L10-like |
| RRP9 | ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast) |
| RUNDC3B | RUN domain containing 3B |
| SCAMP5 | secretory carrier membrane protein 5 |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SCMH1 | sex comb on midleg homolog 1 (Drosophila) |
| SDC3 | syndecan 3 |
| SKI | SKI proto-oncogene |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 |
| SLC26A6 | solute carrier family 26 (anion exchanger), member 6 |
| SNIP1 | Smad nuclear interacting protein 1 |
| SPAG4 | sperm associated antigen 4 |
| STAG3 | stromal antigen 3 |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| TBC1D17 | TBC1 domain family, member 17 |
| TCTA | T-cell leukemia translocation altered |
| TDRD7 | tudor domain containing 7 |
| THOP1 | thimet oligopeptidase 1 |
| TIMM17B | translocase of inner mitochondrial membrane 17 homolog B (yeast) |
| TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) |
| TSPO | translocator protein (18kDa) |
| TUBA3C | tubulin, alpha 3c |
| TUT1 | terminal uridylyl transferase 1, U6 snRNA-specific |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 |
| UNC119 | unc-119 homolog (C. elegans) |
| USB1 | U6 snRNA biogenesis 1 |
| VWA1 | von Willebrand factor A domain containing 1 |
| ZCWPW1 | zinc finger, CW type with PWWP domain 1 |
| ZNF324 | zinc finger protein 324 |
| ZNF701 | zinc finger protein 701 |
| ZNF747 | zinc finger protein 747 |
| ZNF862 | zinc finger protein 862 |