| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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196 genes differentially expressed following the ampyrone-6845 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAK1 | AP2 associated kinase 1 |
| ADGRG1 | adhesion G protein-coupled receptor G1 |
| AEBP1 | AE binding protein 1 |
| ALAD | aminolevulinate dehydratase |
| AP3B2 | adaptor-related protein complex 3, beta 2 subunit |
| APBA3 | amyloid beta (A4) precursor protein-binding, family A, member 3 |
| APOE | apolipoprotein E |
| ARTN | artemin |
| BMP10 | bone morphogenetic protein 10 |
| CA5B | carbonic anhydrase VB, mitochondrial |
| CHN2 | chimerin 2 |
| CHRM3 | cholinergic receptor, muscarinic 3 |
| CTNS | cystinosin, lysosomal cystine transporter |
| CYP2A6 | cytochrome P450, family 2, subfamily A, polypeptide 6 |
| DLC1 | DLC1 Rho GTPase activating protein |
| DNAJB12 | DnaJ (Hsp40) homolog, subfamily B, member 12 |
| DYNC1LI2 | dynein, cytoplasmic 1, light intermediate chain 2 |
| EAF2 | ELL associated factor 2 |
| EFNB3 | ephrin-B3 |
| EHBP1L1 | EH domain binding protein 1-like 1 |
| ELL2 | elongation factor, RNA polymerase II, 2 |
| EMCN | endomucin |
| EPX | eosinophil peroxidase |
| ERCC2 | excision repair cross-complementation group 2 |
| EYA3 | EYA transcriptional coactivator and phosphatase 3 |
| FAM214B | family with sequence similarity 214, member B |
| FBLN1 | fibulin 1 |
| FLOT1 | flotillin 1 |
| GABRD | gamma-aminobutyric acid (GABA) A receptor, delta |
| GABRQ | gamma-aminobutyric acid (GABA) A receptor, theta |
| GALR2 | galanin receptor 2 |
| GPR176 | G protein-coupled receptor 176 |
| HOXB3 | homeobox B3 |
| HTR3A | 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic |
| ICA1 | islet cell autoantigen 1, 69kDa |
| ICAM1 | intercellular adhesion molecule 1 |
| IFI27 | interferon, alpha-inducible protein 27 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFITM1 | interferon induced transmembrane protein 1 |
| IL36G | interleukin 36, gamma |
| KCNAB2 | potassium channel, voltage gated subfamily A regulatory beta subunit 2 |
| KLHL18 | kelch-like family member 18 |
| KRT31 | keratin 31, type I |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| LIN7A | lin-7 homolog A (C. elegans) |
| LINC00472 | long intergenic non-protein coding RNA 472 |
| MAP2 | microtubule-associated protein 2 |
| MAP2K7 | mitogen-activated protein kinase kinase 7 |
| MKL1 | megakaryoblastic leukemia (translocation) 1 |
| MYH14 | myosin, heavy chain 14, non-muscle |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
| MYLK | myosin light chain kinase |
| MYT1 | myelin transcription factor 1 |
| NBL1 | neuroblastoma 1, DAN family BMP antagonist |
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) |
| NPR3 | natriuretic peptide receptor 3 |
| NRL | neural retina leucine zipper |
| OR1D2 | olfactory receptor, family 1, subfamily D, member 2 |
| PAOX | polyamine oxidase (exo-N4-amino) |
| PAPPA2 | pappalysin 2 |
| PCDH12 | protocadherin 12 |
| PMEL | premelanosome protein |
| PXDC1 | PX domain containing 1 |
| RAD52 | RAD52 homolog (S. cerevisiae) |
| RBP4 | retinol binding protein 4, plasma |
| RIMS3 | regulating synaptic membrane exocytosis 3 |
| RNF122 | ring finger protein 122 |
| RS1 | retinoschisin 1 |
| RYR1 | ryanodine receptor 1 (skeletal) |
| S100A7 | S100 calcium binding protein A7 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
| SIGLEC6 | sialic acid binding Ig-like lectin 6 |
| SLC17A2 | solute carrier family 17, member 2 |
| SLC26A4 | solute carrier family 26 (anion exchanger), member 4 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) |
| SULT4A1 | sulfotransferase family 4A, member 1 |
| SWAP70 | SWAP switching B-cell complex 70kDa subunit |
| TAOK2 | TAO kinase 2 |
| TBC1D2 | TBC1 domain family, member 2 |
| TBX5 | T-box 5 |
| TEF | thyrotrophic embryonic factor |
| TPMT | thiopurine S-methyltransferase |
| TRD | T cell receptor delta locus |
| TSC22D2 | TSC22 domain family, member 2 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) |
| WDTC1 | WD and tetratricopeptide repeats 1 |
| WNT2 | wingless-type MMTV integration site family member 2 |
| WSCD1 | WSC domain containing 1 |
| XYLT1 | xylosyltransferase I |
| YY2 | YY2 transcription factor |
| ZBTB44 | zinc finger and BTB domain containing 44 |
| ZCCHC24 | zinc finger, CCHC domain containing 24 |
| ZNF224 | zinc finger protein 224 |
| ZNF235 | zinc finger protein 235 |
| ZNF236 | zinc finger protein 236 |
| ZNF532 | zinc finger protein 532 |
| ZNF747 | zinc finger protein 747 |
| Symbol | Name |
|---|---|
| A1CF | APOBEC1 complementation factor |
| A2M | alpha-2-macroglobulin |
| A4GALT | alpha 1,4-galactosyltransferase |
| ACTL8 | actin-like 8 |
| ADAP2 | ArfGAP with dual PH domains 2 |
| ADGRG2 | adhesion G protein-coupled receptor G2 |
| ALS2CL | ALS2 C-terminal like |
| ASIC3 | acid sensing (proton gated) ion channel 3 |
| ASPHD1 | aspartate beta-hydroxylase domain containing 1 |
| BAK1 | BCL2-antagonist/killer 1 |
| BGLAP | bone gamma-carboxyglutamate (gla) protein |
| C1ORF159 | chromosome 1 open reading frame 159 |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID |
| CBX8 | chromobox homolog 8 |
| CCNO | cyclin O |
| CCT6B | chaperonin containing TCP1, subunit 6B (zeta 2) |
| CIDEB | cell death-inducing DFFA-like effector b |
| CLCF1 | cardiotrophin-like cytokine factor 1 |
| CNKSR1 | connector enhancer of kinase suppressor of Ras 1 |
| CNKSR2 | connector enhancer of kinase suppressor of Ras 2 |
| CTAGE9 | CTAGE family, member 9 |
| CTH | cystathionine gamma-lyase |
| CXORF56 | chromosome X open reading frame 56 |
| CYP17A1 | cytochrome P450, family 17, subfamily A, polypeptide 1 |
| DEAF1 | DEAF1 transcription factor |
| DECR2 | 2,4-dienoyl CoA reductase 2, peroxisomal |
| DMTN | dematin actin binding protein |
| DUSP13 | dual specificity phosphatase 13 |
| EGFL7 | EGF-like-domain, multiple 7 |
| ERMAP | erythroblast membrane-associated protein (Scianna blood group) |
| FAM155B | family with sequence similarity 155, member B |
| FAM46C | family with sequence similarity 46, member C |
| FBXL2 | F-box and leucine-rich repeat protein 2 |
| FRK | fyn-related Src family tyrosine kinase |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| GPR87 | G protein-coupled receptor 87 |
| GPRIN2 | G protein regulated inducer of neurite outgrowth 2 |
| GSTTP1 | glutathione S-transferase theta pseudogene 1 |
| HDAC11 | histone deacetylase 11 |
| HIST2H2AA3 | histone cluster 2, H2aa3 |
| ICAM4 | intercellular adhesion molecule 4 (Landsteiner-Wiener blood group) |
| ICK | intestinal cell (MAK-like) kinase |
| IFI35 | interferon-induced protein 35 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| KDM5C | lysine (K)-specific demethylase 5C |
| KDM7A | lysine (K)-specific demethylase 7A |
| KPTN | kaptin (actin binding protein) |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| LOC390998 | ribosomal protein L10 pseudogene |
| LTBP2 | latent transforming growth factor beta binding protein 2 |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MAP1S | microtubule-associated protein 1S |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 |
| METTL21B | methyltransferase like 21B |
| MMP9 | matrix metallopeptidase 9 |
| MRPL44 | mitochondrial ribosomal protein L44 |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 |
| NT5E | 5'-nucleotidase, ecto (CD73) |
| OR7E156P | olfactory receptor, family 7, subfamily E, member 156 pseudogene |
| PACS1 | phosphofurin acidic cluster sorting protein 1 |
| PCDHGB5 | protocadherin gamma subfamily B, 5 |
| PIGN | phosphatidylinositol glycan anchor biosynthesis, class N |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PLTP | phospholipid transfer protein |
| PODNL1 | podocan-like 1 |
| POLDIP2 | polymerase (DNA-directed), delta interacting protein 2 |
| POLH | polymerase (DNA directed), eta |
| POM121 | POM121 transmembrane nucleoporin |
| PPP2R3B | protein phosphatase 2, regulatory subunit B'', beta |
| PRR4 | proline rich 4 (lacrimal) |
| PRSS22 | protease, serine, 22 |
| RIN2 | Ras and Rab interactor 2 |
| RNASEL | ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SLC12A6 | solute carrier family 12 (potassium/chloride transporter), member 6 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 |
| SLC9A5 | solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5 |
| SLC9A8 | solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8 |
| SMIM14 | small integral membrane protein 14 |
| SNX16 | sorting nexin 16 |
| SSPN | sarcospan |
| TAF13 | TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa |
| TAOK1 | TAO kinase 1 |
| TEP1 | telomerase-associated protein 1 |
| TMEM212 | transmembrane protein 212 |
| USB1 | U6 snRNA biogenesis 1 |
| USP6 | ubiquitin specific peptidase 6 |
| XK | X-linked Kx blood group |
| ZNF253 | zinc finger protein 253 |
| ZNF350 | zinc finger protein 350 |
| ZNF480 | zinc finger protein 480 |
| ZNF516 | zinc finger protein 516 |
| ZNF665 | zinc finger protein 665 |
| ZSCAN26 | zinc finger and SCAN domain containing 26 |