ampyrone Gene Set
Genes
17 genes differentially expressed following the ampyrone small molecule perturbation from the LINCS L1000 CMAP Chemical Perturbation Consensus Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
EPHB2
|
EPH receptor B2
|
4.51268
|
|
HERC3
|
HECT and RLD domain containing E3 ubiquitin protein ligase 3
|
3.72377
|
|
GRK3
|
G protein-coupled receptor kinase 3
|
3.11453
|
|
RAMP2
|
receptor (G protein-coupled) activity modifying protein 2
|
3.09482
|
|
DNMBP
|
dynamin binding protein
|
3.05578
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CANT1
|
calcium activated nucleotidase 1
|
-7.18679
|
|
RBM34
|
RNA binding motif protein 34
|
-3.75942
|
|
STUB1
|
STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
|
-3.56055
|
|
TLK2
|
tousled-like kinase 2
|
-3.45058
|
|
GLI2
|
GLI family zinc finger 2
|
-3.31939
|
|
RNF128
|
ring finger protein 128, E3 ubiquitin protein ligase
|
-3.27782
|
|
METTL13
|
methyltransferase like 13
|
-3.24711
|
|
SLC6A20
|
solute carrier family 6 (proline IMINO transporter), member 20
|
-3.24617
|
|
TFF2
|
trefoil factor 2
|
-3.0486
|
|
CAPN3
|
calpain 3, (p94)
|
-3.02262
|
|
VNN1
|
vanin 1
|
-3.02213
|
|
CHML
|
choroideremia-like (Rab escort protein 2)
|
-3.01192
|
