amrinone-2724 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the amrinone-2724 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ACTA2 actin, alpha 2, smooth muscle, aorta
ADGRL1 adhesion G protein-coupled receptor L1
ALDH4A1 aldehyde dehydrogenase 4 family, member A1
ALDOB aldolase B, fructose-bisphosphate
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
ALS2CL ALS2 C-terminal like
APOM apolipoprotein M
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
ASMTL-AS1 ASMTL antisense RNA 1
ATP9A ATPase, class II, type 9A
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
CAMK4 calcium/calmodulin-dependent protein kinase IV
CCL7 chemokine (C-C motif) ligand 7
CD1E CD1e molecule
CDC42EP2 CDC42 effector protein (Rho GTPase binding) 2
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
CIB2 calcium and integrin binding family member 2
COL4A6 collagen, type IV, alpha 6
CRAT carnitine O-acetyltransferase
CTAG2 cancer/testis antigen 2
DCN decorin
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
EEA1 early endosome antigen 1
EGFR epidermal growth factor receptor
EHMT1 euchromatic histone-lysine N-methyltransferase 1
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
EPB41L5 erythrocyte membrane protein band 4.1 like 5
EPS8L3 EPS8-like 3
EXPH5 exophilin 5
FBXL18 F-box and leucine-rich repeat protein 18
FBXO4 F-box protein 4
FSHB follicle stimulating hormone, beta polypeptide
FUT7 fucosyltransferase 7 (alpha (1,3) fucosyltransferase)
FXYD7 FXYD domain containing ion transport regulator 7
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GULP1 GULP, engulfment adaptor PTB domain containing 1
HIST1H3G histone cluster 1, H3g
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
HRASLS2 HRAS-like suppressor 2
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
HYAL1 hyaluronoglucosaminidase 1
IGHA1 immunoglobulin heavy constant alpha 1
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
ING2 inhibitor of growth family, member 2
ITGB8 integrin, beta 8
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
LAMP1 lysosomal-associated membrane protein 1
LARGE like-glycosyltransferase
LDOC1 leucine zipper, down-regulated in cancer 1
LENEP lens epithelial protein
MARC1 mitochondrial amidoxime reducing component 1
MARC2 mitochondrial amidoxime reducing component 2
MUC2 mucin 2, oligomeric mucus/gel-forming
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
NADK NAD kinase
NCAM1 neural cell adhesion molecule 1
NEFM neurofilament, medium polypeptide
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NID1 nidogen 1
NOS1 nitric oxide synthase 1 (neuronal)
NPHP1 nephronophthisis 1 (juvenile)
OMG oligodendrocyte myelin glycoprotein
OXTR oxytocin receptor
PAPPA2 pappalysin 2
PCDH17 protocadherin 17
PICALM phosphatidylinositol binding clathrin assembly protein
PLCD1 phospholipase C, delta 1
PLD2 phospholipase D2
PLK4 polo-like kinase 4
POLDIP3 polymerase (DNA-directed), delta interacting protein 3
PPP1R37 protein phosphatase 1, regulatory subunit 37
PSMD5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
PURG purine-rich element binding protein G
PVT1 Pvt1 oncogene (non-protein coding)
RAB11B RAB11B, member RAS oncogene family
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila)
RTEL1 regulator of telomere elongation helicase 1
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SIPA1L1 signal-induced proliferation-associated 1 like 1
SLCO2B1 solute carrier organic anion transporter family, member 2B1
SNCA synuclein, alpha (non A4 component of amyloid precursor)
STATH statherin
SYTL2 synaptotagmin-like 2
TAS2R1 taste receptor, type 2, member 1
TBC1D16 TBC1 domain family, member 16
TBX5 T-box 5
TEX12 testis expressed 12
TEX40 testis expressed 40
TPH1 tryptophan hydroxylase 1
TSPY1 testis specific protein, Y-linked 1
WDR25 WD repeat domain 25
XDH xanthine dehydrogenase
ZFPM2 zinc finger protein, FOG family member 2

decreased expression

Symbol Name
ABHD3 abhydrolase domain containing 3
ACADSB acyl-CoA dehydrogenase, short/branched chain
ACTR3B ARP3 actin-related protein 3 homolog B (yeast)
ACVR1 activin A receptor, type I
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
ANXA2P2 annexin A2 pseudogene 2
ARG1 arginase 1
ARMCX4 armadillo repeat containing, X-linked 4
ATAD2B ATPase family, AAA domain containing 2B
BAHD1 bromo adjacent homology domain containing 1
BCORL1 BCL6 corepressor-like 1
BIK BCL2-interacting killer (apoptosis-inducing)
BNC2 basonuclin 2
CA11 carbonic anhydrase XI
CCDC106 coiled-coil domain containing 106
CCDC132 coiled-coil domain containing 132
CCDC57 coiled-coil domain containing 57
CCDC9 coiled-coil domain containing 9
CCL4 chemokine (C-C motif) ligand 4
CD3D CD3d molecule, delta (CD3-TCR complex)
CEP295 centrosomal protein 295kDa
CHM choroideremia (Rab escort protein 1)
CIC capicua transcriptional repressor
CKB creatine kinase, brain
COLQ collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase
CRADD CASP2 and RIPK1 domain containing adaptor with death domain
CTSV cathepsin V
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila)
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
DOCK4 dedicator of cytokinesis 4
EGR2 early growth response 2
ETAA1 Ewing tumor-associated antigen 1
FAM131A family with sequence similarity 131, member A
FER fer (fps/fes related) tyrosine kinase
FGF23 fibroblast growth factor 23
FOXD1 forkhead box D1
GCH1 GTP cyclohydrolase 1
GPR75 G protein-coupled receptor 75
GPRC5C G protein-coupled receptor, class C, group 5, member C
HDAC7 histone deacetylase 7
HIST1H3H histone cluster 1, H3h
HOXC8 homeobox C8
IDI2-AS1 IDI2 antisense RNA 1
IL4R interleukin 4 receptor
INF2 inverted formin, FH2 and WH2 domain containing
KDM5C lysine (K)-specific demethylase 5C
KIAA1107 KIAA1107
KIF17 kinesin family member 17
LINC00597 long intergenic non-protein coding RNA 597
LOC100287590 uncharacterized LOC100287590
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MBIP MAP3K12 binding inhibitory protein 1
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3
MKL2 MKL/myocardin-like 2
MOCS3 molybdenum cofactor synthesis 3
MTCP1 mature T-cell proliferation 1
NRGN neurogranin (protein kinase C substrate, RC3)
OLAH oleoyl-ACP hydrolase
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
PADI2 peptidyl arginine deiminase, type II
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PCDHGB5 protocadherin gamma subfamily B, 5
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PENK proenkephalin
PGP phosphoglycolate phosphatase
PITX2 paired-like homeodomain 2
PLAG1 pleiomorphic adenoma gene 1
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
POR P450 (cytochrome) oxidoreductase
PRICKLE3 prickle homolog 3 (Drosophila)
PRKCZ protein kinase C, zeta
PRR7 proline rich 7 (synaptic)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PYGB phosphorylase, glycogen; brain
RGS19 regulator of G-protein signaling 19
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RHOBTB2 Rho-related BTB domain containing 2
SCUBE3 signal peptide, CUB domain, EGF-like 3
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SLC12A8 solute carrier family 12, member 8
SLC15A3 solute carrier family 15 (oligopeptide transporter), member 3
SLC35E3 solute carrier family 35, member E3
STAG3L4 stromal antigen 3-like 4 (pseudogene)
TBL1Y transducin (beta)-like 1, Y-linked
TM7SF3 transmembrane 7 superfamily member 3
TMC5 transmembrane channel-like 5
TMEM120B transmembrane protein 120B
TMEM180 transmembrane protein 180
TMEM206 transmembrane protein 206
TMEM209 transmembrane protein 209
TNFSF14 tumor necrosis factor (ligand) superfamily, member 14
TRIM22 tripartite motif containing 22
USP6NL USP6 N-terminal like
VILL villin-like
VN1R1 vomeronasal 1 receptor 1
ZBED1 zinc finger, BED-type containing 1
ZNF225 zinc finger protein 225