amrinone-3465 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the amrinone-3465 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12
ARMC4 armadillo repeat containing 4
ATP11A ATPase, class VI, type 11A
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
BMP2K BMP2 inducible kinase
CDK19 cyclin-dependent kinase 19
COL11A2 collagen, type XI, alpha 2
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like
DDR1-AS1 DDR1 antisense RNA 1 (head to head)
DDX52 DEAD (Asp-Glu-Ala-Asp) box polypeptide 52
EPOR erythropoietin receptor
FAM214B family with sequence similarity 214, member B
FAM49B family with sequence similarity 49, member B
FBLN1 fibulin 1
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FILIP1L filamin A interacting protein 1-like
FOSL1 FOS-like antigen 1
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GFER growth factor, augmenter of liver regeneration
GM2A GM2 ganglioside activator
GPATCH4 G patch domain containing 4
HIST1H1D histone cluster 1, H1d
HLA-C major histocompatibility complex, class I, C
HR hair growth associated
IGFBP5 insulin-like growth factor binding protein 5
KDM4C lysine (K)-specific demethylase 4C
LAMP1 lysosomal-associated membrane protein 1
LDB1 LIM domain binding 1
LHX6 LIM homeobox 6
LMNB1 lamin B1
MAP4K1 mitogen-activated protein kinase kinase kinase kinase 1
MCOLN1 mucolipin 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
METTL7A methyltransferase like 7A
MKL1 megakaryoblastic leukemia (translocation) 1
MOCS1 molybdenum cofactor synthesis 1
MPZL2 myelin protein zero-like 2
MSX2 msh homeobox 2
MYO1E myosin IE
MYOF myoferlin
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2)
NDE1 nudE neurodevelopment protein 1
NEK9 NIMA-related kinase 9
NME5 NME/NM23 family member 5
NOL12 nucleolar protein 12
ORAI2 ORAI calcium release-activated calcium modulator 2
PADI1 peptidyl arginine deiminase, type I
PAWR PRKC, apoptosis, WT1, regulator
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PCDHB13 protocadherin beta 13
PHLDB1 pleckstrin homology-like domain, family B, member 1
PIGN phosphatidylinositol glycan anchor biosynthesis, class N
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLA2G1B phospholipase A2, group IB (pancreas)
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PMS2P3 postmeiotic segregation increased 2 pseudogene 3
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PSEN2 presenilin 2
PVR poliovirus receptor
PYCRL pyrroline-5-carboxylate reductase-like
RAB6A RAB6A, member RAS oncogene family
RAD52 RAD52 homolog (S. cerevisiae)
RB1 retinoblastoma 1
RECQL5 RecQ protein-like 5
RHBG Rh family, B glycoprotein (gene/pseudogene)
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RPL13P5 ribosomal protein L13 pseudogene 5
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
S100A12 S100 calcium binding protein A12
SAFB2 scaffold attachment factor B2
SH2B1 SH2B adaptor protein 1
SLC19A1 solute carrier family 19 (folate transporter), member 1
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
SRPX sushi-repeat containing protein, X-linked
STK17A serine/threonine kinase 17a
TAPBP TAP binding protein (tapasin)
TBX19 T-box 19
TEP1 telomerase-associated protein 1
TFE3 transcription factor binding to IGHM enhancer 3
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
THAP9 THAP domain containing 9
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TM2D1 TM2 domain containing 1
TMEM63A transmembrane protein 63A
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
TRAF2 TNF receptor-associated factor 2
TTC9 tetratricopeptide repeat domain 9
USB1 U6 snRNA biogenesis 1
USP19 ubiquitin specific peptidase 19
VEGFB vascular endothelial growth factor B
WWP2 WW domain containing E3 ubiquitin protein ligase 2
ZFYVE9 zinc finger, FYVE domain containing 9
ZNF137P zinc finger protein 137, pseudogene
ZNF573 zinc finger protein 573
ZNF778 zinc finger protein 778
ZNF862 zinc finger protein 862
ZSCAN2 zinc finger and SCAN domain containing 2

decreased expression

Symbol Name
ABLIM3 actin binding LIM protein family, member 3
ACTL8 actin-like 8
AP1G2 adaptor-related protein complex 1, gamma 2 subunit
ASAP1-IT1 ASAP1 intronic transcript 1
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
BAG4 BCL2-associated athanogene 4
BCL2L13 BCL2-like 13 (apoptosis facilitator)
BFSP1 beaded filament structural protein 1, filensin
C14ORF132 chromosome 14 open reading frame 132
C2ORF54 chromosome 2 open reading frame 54
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated
CAPRIN2 caprin family member 2
CCDC69 coiled-coil domain containing 69
CENPO centromere protein O
CENPT centromere protein T
CEP170B centrosomal protein 170B
CLCN2 chloride channel, voltage-sensitive 2
CNGB3 cyclic nucleotide gated channel beta 3
CNPY3 canopy FGF signaling regulator 3
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa
CST6 cystatin E/M
DEAF1 DEAF1 transcription factor
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
FAM131A family with sequence similarity 131, member A
FBXO46 F-box protein 46
FCHO1 FCH domain only 1
FKBP5 FK506 binding protein 5
FLT4 fms-related tyrosine kinase 4
FRK fyn-related Src family tyrosine kinase
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
GPR143 G protein-coupled receptor 143
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HIST1H2BI histone cluster 1, H2bi
HMG20A high mobility group 20A
IGSF1 immunoglobulin superfamily, member 1
KATNBL1 katanin p80 subunit B-like 1
KCNK12 potassium channel, two pore domain subfamily K, member 12
KCTD15 potassium channel tetramerization domain containing 15
KDM7A lysine (K)-specific demethylase 7A
KLC2 kinesin light chain 2
LIG3 ligase III, DNA, ATP-dependent
LIG4 ligase IV, DNA, ATP-dependent
LMBR1L limb development membrane protein 1-like
LPAR4 lysophosphatidic acid receptor 4
LZTFL1 leucine zipper transcription factor-like 1
MAST3 microtubule associated serine/threonine kinase 3
MBTD1 mbt domain containing 1
MECR mitochondrial trans-2-enoyl-CoA reductase
MTCL1 microtubule crosslinking factor 1
NECAB3 N-terminal EF-hand calcium binding protein 3
NPY1R neuropeptide Y receptor Y1
NR1H2 nuclear receptor subfamily 1, group H, member 2
NUS1P3 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3
PARP16 poly (ADP-ribose) polymerase family, member 16
PEX26 peroxisomal biogenesis factor 26
PGPEP1 pyroglutamyl-peptidase I
PITX2 paired-like homeodomain 2
PLA2G3 phospholipase A2, group III
PRICKLE3 prickle homolog 3 (Drosophila)
RASAL1 RAS protein activator like 1 (GAP1 like)
RCBTB1 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1
RPAP1 RNA polymerase II associated protein 1
RWDD3 RWD domain containing 3
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SIRT6 sirtuin 6
SKA1 spindle and kinetochore associated complex subunit 1
SLC12A9 solute carrier family 12, member 9
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8
SLC36A1 solute carrier family 36 (proton/amino acid symporter), member 1
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SNX15 sorting nexin 15
SPINK4 serine peptidase inhibitor, Kazal type 4
SRD5A3 steroid 5 alpha-reductase 3
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STAG3L1 stromal antigen 3-like 1 (pseudogene)
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TBC1D19 TBC1 domain family, member 19
TBC1D31 TBC1 domain family, member 31
TEAD3 TEA domain family member 3
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TMEM104 transmembrane protein 104
TMEM110 transmembrane protein 110
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TRNAU1AP tRNA selenocysteine 1 associated protein 1
TSPAN15 tetraspanin 15
UNC119 unc-119 homolog (C. elegans)
VPS37B vacuolar protein sorting 37 homolog B (S. cerevisiae)
WDR7 WD repeat domain 7
XAB2 XPA binding protein 2
ZBTB48 zinc finger and BTB domain containing 48
ZMYM1 zinc finger, MYM-type 1
ZNF282 zinc finger protein 282
ZNF324 zinc finger protein 324
ZNF696 zinc finger protein 696