amrinone-4488 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the amrinone-4488 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAMDC adipogenesis associated, Mth938 domain containing
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ADH1A alcohol dehydrogenase 1A (class I), alpha polypeptide
ANGEL2 angel homolog 2 (Drosophila)
ANKLE2 ankyrin repeat and LEM domain containing 2
ARHGAP44 Rho GTPase activating protein 44
ARID4B AT rich interactive domain 4B (RBP1-like)
ATP8A1 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
ATXN7L1 ataxin 7-like 1
BAAT bile acid CoA:amino acid N-acyltransferase
BGN biglycan
BMP10 bone morphogenetic protein 10
BTG2 BTG family, member 2
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CEACAM4 carcinoembryonic antigen-related cell adhesion molecule 4
CEP41 centrosomal protein 41kDa
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CLEC4E C-type lectin domain family 4, member E
CNGA1 cyclic nucleotide gated channel alpha 1
COL9A3 collagen, type IX, alpha 3
COPG2IT1 COPG2 imprinted transcript 1 (non-protein coding)
CROCC ciliary rootlet coiled-coil, rootletin
CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12
DMXL2 Dmx-like 2
DTX3 deltex 3, E3 ubiquitin ligase
E2F5 E2F transcription factor 5, p130-binding
ECE1 endothelin converting enzyme 1
ELOVL2 ELOVL fatty acid elongase 2
EPS15L1 epidermal growth factor receptor pathway substrate 15-like 1
ESRRG estrogen-related receptor gamma
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
FFAR3 free fatty acid receptor 3
FGFR4 fibroblast growth factor receptor 4
FOXO4 forkhead box O4
FZD10 frizzled class receptor 10
GPR68 G protein-coupled receptor 68
GRIP2 glutamate receptor interacting protein 2
HBE1 hemoglobin, epsilon 1
HFE hemochromatosis
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
IBSP integrin-binding sialoprotein
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IQCC IQ motif containing C
ITGA7 integrin, alpha 7
JAK3 Janus kinase 3
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KHK ketohexokinase (fructokinase)
KLHL22 kelch-like family member 22
KRTAP2-4 keratin associated protein 2-4
LRP2 low density lipoprotein receptor-related protein 2
LRRTM2 leucine rich repeat transmembrane neuronal 2
MADCAM1 mucosal vascular addressin cell adhesion molecule 1
MFGE8 milk fat globule-EGF factor 8 protein
MLANA melan-A
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MMP25 matrix metallopeptidase 25
MS4A1 membrane-spanning 4-domains, subfamily A, member 1
MVD mevalonate (diphospho) decarboxylase
MYL10 myosin, light chain 10, regulatory
NEBL nebulette
NIPAL2 NIPA-like domain containing 2
NPR2 natriuretic peptide receptor 2
NRF1 nuclear respiratory factor 1
NSUN6 NOP2/Sun domain family, member 6
OLFM1 olfactomedin 1
PDE4DIP phosphodiesterase 4D interacting protein
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLA2G3 phospholipase A2, group III
PPIAL4A peptidylprolyl isomerase A (cyclophilin A)-like 4A
PTCH1 patched 1
PTPRH protein tyrosine phosphatase, receptor type, H
RALGPS1 Ral GEF with PH domain and SH3 binding motif 1
RUNX1 runt-related transcription factor 1
SH2B1 SH2B adaptor protein 1
SH3BP2 SH3-domain binding protein 2
SHOX2 short stature homeobox 2
SMAD5 SMAD family member 5
SOCS3 suppressor of cytokine signaling 3
SPSB3 splA/ryanodine receptor domain and SOCS box containing 3
SYMPK symplekin
TAT tyrosine aminotransferase
TCP11L1 t-complex 11, testis-specific-like 1
TDRD1 tudor domain containing 1
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
TIMM8A translocase of inner mitochondrial membrane 8 homolog A (yeast)
TLDC1 TBC/LysM-associated domain containing 1
TRIL TLR4 interactor with leucine-rich repeats
TRIM3 tripartite motif containing 3
UBE3A ubiquitin protein ligase E3A
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17
UNC13A unc-13 homolog A (C. elegans)
ZBTB17 zinc finger and BTB domain containing 17
ZKSCAN8 zinc finger with KRAB and SCAN domains 8
ZNF3 zinc finger protein 3
ZNF362 zinc finger protein 362

decreased expression

Symbol Name
AADAC arylacetamide deacetylase
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2
ADGRB2 adhesion G protein-coupled receptor B2
ANXA2P1 annexin A2 pseudogene 1
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
APLP1 amyloid beta (A4) precursor-like protein 1
ARMCX4 armadillo repeat containing, X-linked 4
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
BIRC3 baculoviral IAP repeat containing 3
BTC betacellulin
C19ORF40 chromosome 19 open reading frame 40
CCDC9 coiled-coil domain containing 9
CCL27 chemokine (C-C motif) ligand 27
CD101 CD101 molecule
CD70 CD70 molecule
CDK3 cyclin-dependent kinase 3
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
CISH cytokine inducible SH2-containing protein
CORO1A coronin, actin binding protein, 1A
CREB5 cAMP responsive element binding protein 5
CTDNEP1 CTD nuclear envelope phosphatase 1
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
DGKE diacylglycerol kinase, epsilon 64kDa
DMTN dematin actin binding protein
DOC2A double C2-like domains, alpha
ELP6 elongator acetyltransferase complex subunit 6
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
ERN2 endoplasmic reticulum to nucleus signaling 2
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
GLS2 glutaminase 2 (liver, mitochondrial)
GRB7 growth factor receptor-bound protein 7
GTF2A1 general transcription factor IIA, 1, 19/37kDa
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HDAC7 histone deacetylase 7
HIRA histone cell cycle regulator
HIST1H1D histone cluster 1, H1d
HIST1H2AG histone cluster 1, H2ag
HIST1H2BJ histone cluster 1, H2bj
HLA-DMA major histocompatibility complex, class II, DM alpha
HLX H2.0-like homeobox
HOOK1 hook microtubule-tethering protein 1
HOXC5 homeobox C5
INPP5A inositol polyphosphate-5-phosphatase, 40kDa
ISYNA1 inositol-3-phosphate synthase 1
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KIAA0513 KIAA0513
KIAA0754 KIAA0754
KIAA0895 KIAA0895
LIMS2 LIM and senescent cell antigen-like domains 2
LIN7B lin-7 homolog B (C. elegans)
LINC00260 long intergenic non-protein coding RNA 260
LINC00339 long intergenic non-protein coding RNA 339
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MRPL44 mitochondrial ribosomal protein L44
MTMR6 myotubularin related protein 6
MYH15 myosin, heavy chain 15
NPIPB15 nuclear pore complex interacting protein family, member B15
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PARP6 poly (ADP-ribose) polymerase family, member 6
PCDHGB5 protocadherin gamma subfamily B, 5
PDE12 phosphodiesterase 12
PLEKHO1 pleckstrin homology domain containing, family O member 1
POLL polymerase (DNA directed), lambda
PPP1R13B protein phosphatase 1, regulatory subunit 13B
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta
PRB3 proline-rich protein BstNI subfamily 3
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
RAB5B RAB5B, member RAS oncogene family
RFWD3 ring finger and WD repeat domain 3
RNF126P1 ring finger protein 126 pseudogene 1
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
SETBP1 SET binding protein 1
SETD8 SET domain containing (lysine methyltransferase) 8
SH3TC1 SH3 domain and tetratricopeptide repeats 1
SLC9A5 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
SMR3A submaxillary gland androgen regulated protein 3A
SRD5A3 steroid 5 alpha-reductase 3
SYT17 synaptotagmin XVII
TEP1 telomerase-associated protein 1
TMSB15A thymosin beta 15a
TRMT2B tRNA methyltransferase 2 homolog B (S. cerevisiae)
TSPAN12 tetraspanin 12
VEZT vezatin, adherens junctions transmembrane protein
WDR4 WD repeat domain 4
WDR76 WD repeat domain 76
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
YY2 YY2 transcription factor
ZNF230 zinc finger protein 230
ZNF573 zinc finger protein 573
ZNF652 zinc finger protein 652
ZNF667 zinc finger protein 667
ZNF778 zinc finger protein 778
ZW10 zw10 kinetochore protein