amrinone-6826 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the amrinone-6826 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ACRV1 acrosomal vesicle protein 1
ADCY2 adenylate cyclase 2 (brain)
APOC1 apolipoprotein C-I
APOM apolipoprotein M
ARTN artemin
ATP2A1 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
BHLHE41 basic helix-loop-helix family, member e41
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
CAV2 caveolin 2
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal)
CLDN11 claudin 11
CLGN calmegin
CNTN1 contactin 1
CSF2RA colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
CTNS cystinosin, lysosomal cystine transporter
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
DFNB31 deafness, autosomal recessive 31
DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4
DPY19L1P1 DPY19L1 pseudogene 1
DSC3 desmocollin 3
EFCAB6 EF-hand calcium binding domain 6
ERP44 endoplasmic reticulum protein 44
EXOSC2 exosome component 2
FGF18 fibroblast growth factor 18
FLJ11710 uncharacterized protein FLJ11710
FSCN1 fascin actin-bundling protein 1
FSHB follicle stimulating hormone, beta polypeptide
FXYD5 FXYD domain containing ion transport regulator 5
GEMIN8 gem (nuclear organelle) associated protein 8
GLDC glycine dehydrogenase (decarboxylating)
GLIPR1 GLI pathogenesis-related 1
GLP1R glucagon-like peptide 1 receptor
GPR176 G protein-coupled receptor 176
GRM1 glutamate receptor, metabotropic 1
HIST1H3I histone cluster 1, H3i
HIST1H4C histone cluster 1, H4c
HPCAL4 hippocalcin like 4
INE1 inactivation escape 1 (non-protein coding)
KLRF1 killer cell lectin-like receptor subfamily F, member 1
LIMK1 LIM domain kinase 1
LINC00302 long intergenic non-protein coding RNA 302
LOC100131532 uncharacterized LOC100131532
LOC157562 uncharacterized LOC157562
LPCAT4 lysophosphatidylcholine acyltransferase 4
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
MAPK14 mitogen-activated protein kinase 14
MAPK7 mitogen-activated protein kinase 7
MBNL3 muscleblind-like splicing regulator 3
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MED9 mediator complex subunit 9
MOB1A MOB kinase activator 1A
MTMR8 myotubularin related protein 8
MYO9B myosin IXB
NDUFA2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NPPA natriuretic peptide A
NPY1R neuropeptide Y receptor Y1
NR2E3 nuclear receptor subfamily 2, group E, member 3
NR3C2 nuclear receptor subfamily 3, group C, member 2
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OSBPL10 oxysterol binding protein-like 10
OSGIN1 oxidative stress induced growth inhibitor 1
PAX2 paired box 2
PCDHGA8 protocadherin gamma subfamily A, 8
PDE4DIP phosphodiesterase 4D interacting protein
PGAP3 post-GPI attachment to proteins 3
PIN1P1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 pseudogene 1
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLEKHG3 pleckstrin homology domain containing, family G (with RhoGef domain) member 3
PPARD peroxisome proliferator-activated receptor delta
PPP2R5B protein phosphatase 2, regulatory subunit B', beta
PRTN3 proteinase 3
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1
PYHIN1 pyrin and HIN domain family, member 1
RAB40AL RAB40A, member RAS oncogene family-like
RIN3 Ras and Rab interactor 3
RNF39 ring finger protein 39
RQCD1 RCD1 required for cell differentiation1 homolog (S. pombe)
SERGEF secretion regulating guanine nucleotide exchange factor
SIRT5 sirtuin 5
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC35E2 solute carrier family 35, member E2
SLCO2A1 solute carrier organic anion transporter family, member 2A1
SOX9 SRY (sex determining region Y)-box 9
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
SPTBN5 spectrin, beta, non-erythrocytic 5
STAM2 signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
TAAR5 trace amine associated receptor 5
TFDP3 transcription factor Dp family, member 3
TMEM242 transmembrane protein 242
TNC tenascin C
TPR translocated promoter region, nuclear basket protein
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
ZNF646 zinc finger protein 646

decreased expression

Symbol Name
AAAS achalasia, adrenocortical insufficiency, alacrimia
ADAP2 ArfGAP with dual PH domains 2
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)
ANO10 anoctamin 10
ARC activity-regulated cytoskeleton-associated protein
ARSB arylsulfatase B
ATXN2 ataxin 2
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
BCORL1 BCL6 corepressor-like 1
BTF3P11 basic transcription factor 3 pseudogene 11
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
C5AR2 complement component 5a receptor 2
CAMK1D calcium/calmodulin-dependent protein kinase ID
CCDC71 coiled-coil domain containing 71
CCNE1 cyclin E1
CNKSR2 connector enhancer of kinase suppressor of Ras 2
CPTP ceramide-1-phosphate transfer protein
CRIP1 cysteine-rich protein 1 (intestinal)
CXADR coxsackie virus and adenovirus receptor
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DDIT3 DNA-damage-inducible transcript 3
DEAF1 DEAF1 transcription factor
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DYSF dysferlin
EPN2 epsin 2
EXTL2 exostosin-like glycosyltransferase 2
FAM169A family with sequence similarity 169, member A
GAMT guanidinoacetate N-methyltransferase
GBP2 guanylate binding protein 2, interferon-inducible
GLB1L2 galactosidase, beta 1-like 2
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GPRIN2 G protein regulated inducer of neurite outgrowth 2
GSTA4 glutathione S-transferase alpha 4
GSTTP1 glutathione S-transferase theta pseudogene 1
GUSBP3 glucuronidase, beta pseudogene 3
HMOX1 heme oxygenase 1
HYI hydroxypyruvate isomerase (putative)
IFT140 intraflagellar transport 140
IL20RA interleukin 20 receptor, alpha
KAT2A K(lysine) acetyltransferase 2A
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KCTD15 potassium channel tetramerization domain containing 15
KRT15 keratin 15, type I
LAMB3 laminin, beta 3
LGALS4 lectin, galactoside-binding, soluble, 4
LHX6 LIM homeobox 6
LIME1 Lck interacting transmembrane adaptor 1
LINC00115 long intergenic non-protein coding RNA 115
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
OSMR oncostatin M receptor
PADI3 peptidyl arginine deiminase, type III
PCDHB13 protocadherin beta 13
PCSK7 proprotein convertase subtilisin/kexin type 7
PGBD5 piggyBac transposable element derived 5
PLD2 phospholipase D2
PP14571 uncharacterized LOC100130449
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta
PROCR protein C receptor, endothelial
PSG4 pregnancy specific beta-1-glycoprotein 4
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RGS2 regulator of G-protein signaling 2
RNF126P1 ring finger protein 126 pseudogene 1
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
SCAMP5 secretory carrier membrane protein 5
SCGB2A2 secretoglobin, family 2A, member 2
SDC3 syndecan 3
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SLC16A2 solute carrier family 16, member 2 (thyroid hormone transporter)
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC22A14 solute carrier family 22, member 14
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SMIM14 small integral membrane protein 14
SPAG4 sperm associated antigen 4
SPINK5 serine peptidase inhibitor, Kazal type 5
SSBP3 single stranded DNA binding protein 3
STRN striatin, calmodulin binding protein
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TAOK1 TAO kinase 1
TCTA T-cell leukemia translocation altered
THG1L tRNA-histidine guanylyltransferase 1-like (S. cerevisiae)
TLN1 talin 1
TLR5 toll-like receptor 5
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TRABD TraB domain containing
TRIM21 tripartite motif containing 21
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TTC17 tetratricopeptide repeat domain 17
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
UBTD1 ubiquitin domain containing 1
UPP1 uridine phosphorylase 1
USB1 U6 snRNA biogenesis 1
VASH1 vasohibin 1
ZFHX3 zinc finger homeobox 3
ZNF324 zinc finger protein 324
ZNF451 zinc finger protein 451
ZNF552 zinc finger protein 552