amylocaine-1909 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the amylocaine-1909 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AARSD1 alanyl-tRNA synthetase domain containing 1
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
APOM apolipoprotein M
ARMC6 armadillo repeat containing 6
ASMTL acetylserotonin O-methyltransferase-like
ATP13A2 ATPase type 13A2
ATXN2 ataxin 2
BAZ2A bromodomain adjacent to zinc finger domain, 2A
BCAS4 breast carcinoma amplified sequence 4
BTG2 BTG family, member 2
C11ORF24 chromosome 11 open reading frame 24
C19ORF66 chromosome 19 open reading frame 66
C1QTNF1 C1q and tumor necrosis factor related protein 1
C21ORF33 chromosome 21 open reading frame 33
CBX7 chromobox homolog 7
CEACAM4 carcinoembryonic antigen-related cell adhesion molecule 4
CHD3 chromodomain helicase DNA binding protein 3
CIAO1 cytosolic iron-sulfur assembly component 1
CLDN11 claudin 11
CLDN15 claudin 15
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
DCLRE1A DNA cross-link repair 1A
DCTN1 dynactin 1
DHRS2 dehydrogenase/reductase (SDR family) member 2
DTNA dystrobrevin, alpha
DUSP6 dual specificity phosphatase 6
FADS2 fatty acid desaturase 2
FASTK Fas-activated serine/threonine kinase
FGFR1 fibroblast growth factor receptor 1
GAB2 GRB2-associated binding protein 2
GALNT11 polypeptide N-acetylgalactosaminyltransferase 11
GBX2 gastrulation brain homeobox 2
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2
GMIP GEM interacting protein
GPR4 G protein-coupled receptor 4
HDAC7 histone deacetylase 7
HIF1AN hypoxia inducible factor 1, alpha subunit inhibitor
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
KIF2A kinesin heavy chain member 2A
KIRREL kin of IRRE like (Drosophila)
KLHL18 kelch-like family member 18
LAMC3 laminin, gamma 3
LRFN4 leucine rich repeat and fibronectin type III domain containing 4
MANBA mannosidase, beta A, lysosomal
MDC1 mediator of DNA-damage checkpoint 1
MED8 mediator complex subunit 8
MICALL1 MICAL-like 1
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MXD4 MAX dimerization protein 4
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NXPH3 neurexophilin 3
NXT2 nuclear transport factor 2-like export factor 2
OGFR opioid growth factor receptor
PAK1IP1 PAK1 interacting protein 1
PALM paralemmin
PCGF2 polycomb group ring finger 2
PCSK7 proprotein convertase subtilisin/kexin type 7
PDE4DIP phosphodiesterase 4D interacting protein
PDK2 pyruvate dehydrogenase kinase, isozyme 2
PLEKHG3 pleckstrin homology domain containing, family G (with RhoGef domain) member 3
PMM1 phosphomannomutase 1
PMS2P3 postmeiotic segregation increased 2 pseudogene 3
PPDPF pancreatic progenitor cell differentiation and proliferation factor
PPP6R2 protein phosphatase 6, regulatory subunit 2
PRKD2 protein kinase D2
PRPF31 pre-mRNA processing factor 31
PTBP3 polypyrimidine tract binding protein 3
PTGDS prostaglandin D2 synthase 21kDa (brain)
PYGB phosphorylase, glycogen; brain
QTRT1 queuine tRNA-ribosyltransferase 1
REPS2 RALBP1 associated Eps domain containing 2
RNF123 ring finger protein 123
RRBP1 ribosome binding protein 1
SAFB2 scaffold attachment factor B2
SAG S-antigen; retina and pineal gland (arrestin)
SARM1 sterile alpha and TIR motif containing 1
SEZ6L seizure related 6 homolog (mouse)-like
SGK2 serum/glucocorticoid regulated kinase 2
SH3BP5 SH3-domain binding protein 5 (BTK-associated)
SLC10A1 solute carrier family 10 (sodium/bile acid cotransporter), member 1
SLC24A2 solute carrier family 24 (sodium/potassium/calcium exchanger), member 2
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5
SREBF1 sterol regulatory element binding transcription factor 1
TCL1A T-cell leukemia/lymphoma 1A
THBS3 thrombospondin 3
THTPA thiamine triphosphatase
TMEM159 transmembrane protein 159
TP53I11 tumor protein p53 inducible protein 11
USF2 upstream transcription factor 2, c-fos interacting
WDR18 WD repeat domain 18
WDR74 WD repeat domain 74
WDTC1 WD and tetratricopeptide repeats 1
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
XYLT2 xylosyltransferase II
ZNF134 zinc finger protein 134
ZNF408 zinc finger protein 408
ZNF79 zinc finger protein 79

decreased expression

Symbol Name
ABHD3 abhydrolase domain containing 3
ACADM acyl-CoA dehydrogenase, C-4 to C-12 straight chain
ACTL6A actin-like 6A
AHR aryl hydrocarbon receptor
AMOTL2 angiomotin like 2
ANKRA2 ankyrin repeat, family A (RFXANK-like), 2
ANKS1A ankyrin repeat and sterile alpha motif domain containing 1A
ARFGAP3 ADP-ribosylation factor GTPase activating protein 3
ATF1 activating transcription factor 1
BAHD1 bromo adjacent homology domain containing 1
BCL2L13 BCL2-like 13 (apoptosis facilitator)
BRIX1 BRX1, biogenesis of ribosomes
C12ORF29 chromosome 12 open reading frame 29
C1ORF115 chromosome 1 open reading frame 115
CASZ1 castor zinc finger 1
CHUK conserved helix-loop-helix ubiquitous kinase
CLASP1 cytoplasmic linker associated protein 1
CLK4 CDC-like kinase 4
CPOX coproporphyrinogen oxidase
CRIPT cysteine-rich PDZ-binding protein
CXCL2 chemokine (C-X-C motif) ligand 2
CXCL3 chemokine (C-X-C motif) ligand 3
CXCL6 chemokine (C-X-C motif) ligand 6
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1
DMBT1 deleted in malignant brain tumors 1
DMXL1 Dmx-like 1
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3
ERBB2IP erbb2 interacting protein
FAIM Fas apoptotic inhibitory molecule
FBXO5 F-box protein 5
FPGT fucose-1-phosphate guanylyltransferase
GCLM glutamate-cysteine ligase, modifier subunit
GGNBP2 gametogenetin binding protein 2
GRPR gastrin-releasing peptide receptor
GTF3C4 general transcription factor IIIC, polypeptide 4, 90kDa
H1FX H1 histone family, member X
HACD2 3-hydroxyacyl-CoA dehydratase 2
HSPA1A heat shock 70kDa protein 1A
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IL17RA interleukin 17 receptor A
ISOC1 isochorismatase domain containing 1
KLHL2 kelch-like family member 2
KRT34 keratin 34, type I
LGR4 leucine-rich repeat containing G protein-coupled receptor 4
LIN7C lin-7 homolog C (C. elegans)
LRCH3 leucine-rich repeats and calponin homology (CH) domain containing 3
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast)
MBD5 methyl-CpG binding domain protein 5
MSMO1 methylsterol monooxygenase 1
MYL12B myosin, light chain 12B, regulatory
MYNN myoneurin
NEK7 NIMA-related kinase 7
NOL8 nucleolar protein 8
NUPL2 nucleoporin like 2
OSTM1 osteopetrosis associated transmembrane protein 1
PCDHGB5 protocadherin gamma subfamily B, 5
PCNXL4 pecanex-like 4 (Drosophila)
PDCD10 programmed cell death 10
PEX11B peroxisomal biogenesis factor 11 beta
PTBP2 polypyrimidine tract binding protein 2
PTX3 pentraxin 3, long
QTRTD1 queuine tRNA-ribosyltransferase domain containing 1
RAB17 RAB17, member RAS oncogene family
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1
RAP1GAP2 RAP1 GTPase activating protein 2
RIPPLY3 ripply transcriptional repressor 3
SH2D2A SH2 domain containing 2A
SH3YL1 SH3 and SYLF domain containing 1
SLC25A24 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24
SLC39A1 solute carrier family 39 (zinc transporter), member 1
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SNAI2 snail family zinc finger 2
SRP19 signal recognition particle 19kDa
STXBP1 syntaxin binding protein 1
TASP1 taspase, threonine aspartase, 1
TCERG1 transcription elongation regulator 1
TGS1 trimethylguanosine synthase 1
THAP7 THAP domain containing 7
TMEM110 transmembrane protein 110
TMEM2 transmembrane protein 2
TOP2B topoisomerase (DNA) II beta 180kDa
TOPBP1 topoisomerase (DNA) II binding protein 1
TP53BP2 tumor protein p53 binding protein 2
TRMT11 tRNA methyltransferase 11 homolog (S. cerevisiae)
TSPYL2 TSPY-like 2
TTC23 tetratricopeptide repeat domain 23
TUBB2A tubulin, beta 2A class IIa
UBXN2B UBX domain protein 2B
UGDH UDP-glucose 6-dehydrogenase
VPS4B vacuolar protein sorting 4 homolog B (S. cerevisiae)
WDR37 WD repeat domain 37
WDR5B WD repeat domain 5B
XPC xeroderma pigmentosum, complementation group C
YRDC yrdC N(6)-threonylcarbamoyltransferase domain containing
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF226 zinc finger protein 226
ZNF302 zinc finger protein 302
ZNF32 zinc finger protein 32