| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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200 genes differentially expressed following the amylocaine-1991 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCC1 | ATP-binding cassette, sub-family C (CFTR/MRP), member 1 |
| ACAA2 | acetyl-CoA acyltransferase 2 |
| ADAM8 | ADAM metallopeptidase domain 8 |
| ADAMTS2 | ADAM metallopeptidase with thrombospondin type 1 motif, 2 |
| ADGRL1 | adhesion G protein-coupled receptor L1 |
| AHCYL2 | adenosylhomocysteinase-like 2 |
| AKAP13 | A kinase (PRKA) anchor protein 13 |
| ALDOB | aldolase B, fructose-bisphosphate |
| APAF1 | apoptotic peptidase activating factor 1 |
| APOC4 | apolipoprotein C-IV |
| ARFIP1 | ADP-ribosylation factor interacting protein 1 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 |
| ATG4B | autophagy related 4B, cysteine peptidase |
| ATP2C1 | ATPase, Ca++ transporting, type 2C, member 1 |
| ATP6V0A2 | ATPase, H+ transporting, lysosomal V0 subunit a2 |
| BCL7A | B-cell CLL/lymphoma 7A |
| C5ORF45 | chromosome 5 open reading frame 45 |
| CA12 | carbonic anhydrase XII |
| CD2BP2 | CD2 (cytoplasmic tail) binding protein 2 |
| CIB2 | calcium and integrin binding family member 2 |
| CLSPN | claspin |
| DDX54 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 |
| DIO2 | deiodinase, iodothyronine, type II |
| DOK2 | docking protein 2, 56kDa |
| DUSP2 | dual specificity phosphatase 2 |
| ELOVL6 | ELOVL fatty acid elongase 6 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 |
| ETV5 | ets variant 5 |
| FBXO3 | F-box protein 3 |
| FHL1 | four and a half LIM domains 1 |
| FLJ10038 | uncharacterized protein FLJ10038 |
| FRMD8 | FERM domain containing 8 |
| FURIN | furin (paired basic amino acid cleaving enzyme) |
| GCNT1 | glucosaminyl (N-acetyl) transferase 1, core 2 |
| GH1 | growth hormone 1 |
| GLI3 | GLI family zinc finger 3 |
| GNG3 | guanine nucleotide binding protein (G protein), gamma 3 |
| GRPR | gastrin-releasing peptide receptor |
| HEMK1 | HemK methyltransferase family member 1 |
| HLA-DMB | major histocompatibility complex, class II, DM beta |
| HOXD1 | homeobox D1 |
| HTR3A | 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 |
| KIFC1 | kinesin family member C1 |
| KLK5 | kallikrein-related peptidase 5 |
| LINC00339 | long intergenic non-protein coding RNA 339 |
| LPP | LIM domain containing preferred translocation partner in lipoma |
| MAGED2 | melanoma antigen family D2 |
| MAP3K9 | mitogen-activated protein kinase kinase kinase 9 |
| NADK | NAD kinase |
| NLE1 | notchless homolog 1 (Drosophila) |
| NOS1 | nitric oxide synthase 1 (neuronal) |
| NPRL3 | nitrogen permease regulator-like 3 (S. cerevisiae) |
| NRP2 | neuropilin 2 |
| NTAN1 | N-terminal asparagine amidase |
| OBFC1 | oligonucleotide/oligosaccharide-binding fold containing 1 |
| ORAI2 | ORAI calcium release-activated calcium modulator 2 |
| OSGEPL1 | O-sialoglycoprotein endopeptidase-like 1 |
| PADI4 | peptidyl arginine deiminase, type IV |
| PALM | paralemmin |
| PCDHGB5 | protocadherin gamma subfamily B, 5 |
| PDE1C | phosphodiesterase 1C, calmodulin-dependent 70kDa |
| PDLIM2 | PDZ and LIM domain 2 (mystique) |
| PIDD1 | p53-induced death domain protein 1 |
| PIP4K2C | phosphatidylinositol-5-phosphate 4-kinase, type II, gamma |
| PLA2G6 | phospholipase A2, group VI (cytosolic, calcium-independent) |
| PNPLA4 | patatin-like phospholipase domain containing 4 |
| POLD4 | polymerase (DNA-directed), delta 4, accessory subunit |
| POTEKP | POTE ankyrin domain family, member K, pseudogene |
| PSG4 | pregnancy specific beta-1-glycoprotein 4 |
| RAB8B | RAB8B, member RAS oncogene family |
| RAP1GAP | RAP1 GTPase activating protein |
| RBM5 | RNA binding motif protein 5 |
| RPAP2 | RNA polymerase II associated protein 2 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) |
| SH2B1 | SH2B adaptor protein 1 |
| SLC10A2 | solute carrier family 10 (sodium/bile acid cotransporter), member 2 |
| SMARCA5 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 |
| SNX13 | sorting nexin 13 |
| SOX4 | SRY (sex determining region Y)-box 4 |
| TCAF1 | TRPM8 channel-associated factor 1 |
| TCP11L1 | t-complex 11, testis-specific-like 1 |
| TINF2 | TERF1 (TRF1)-interacting nuclear factor 2 |
| TOLLIP | toll interacting protein |
| TOM1 | target of myb1 (chicken) |
| TRAF6 | TNF receptor-associated factor 6, E3 ubiquitin protein ligase |
| TRD | T cell receptor delta locus |
| TRIM3 | tripartite motif containing 3 |
| TRIP10 | thyroid hormone receptor interactor 10 |
| TVP23B | trans-golgi network vesicle protein 23 homolog B (S. cerevisiae) |
| TYMP | thymidine phosphorylase |
| UBE2NL | ubiquitin-conjugating enzyme E2N-like (gene/pseudogene) |
| UNC45A | unc-45 homolog A (C. elegans) |
| USP2 | ubiquitin specific peptidase 2 |
| WDR60 | WD repeat domain 60 |
| WWC3 | WWC family member 3 |
| YKT6 | YKT6 v-SNARE homolog (S. cerevisiae) |
| ZC3H3 | zinc finger CCCH-type containing 3 |
| ZMYM2 | zinc finger, MYM-type 2 |
| ZNF219 | zinc finger protein 219 |
| Symbol | Name |
|---|---|
| ABHD3 | abhydrolase domain containing 3 |
| ACYP1 | acylphosphatase 1, erythrocyte (common) type |
| ADCY7 | adenylate cyclase 7 |
| ADI1 | acireductone dioxygenase 1 |
| ALDOC | aldolase C, fructose-bisphosphate |
| ALG6 | ALG6, alpha-1,3-glucosyltransferase |
| ANXA6 | annexin A6 |
| APH1B | APH1B gamma secretase subunit |
| APIP | APAF1 interacting protein |
| ARL4A | ADP-ribosylation factor-like 4A |
| ATPIF1 | ATPase inhibitory factor 1 |
| ATXN2 | ataxin 2 |
| BCL7C | B-cell CLL/lymphoma 7C |
| BTNL3 | butyrophilin-like 3 |
| C6ORF47 | chromosome 6 open reading frame 47 |
| CAMTA2 | calmodulin binding transcription activator 2 |
| CBS | cystathionine-beta-synthase |
| CD48 | CD48 molecule |
| CDCA8 | cell division cycle associated 8 |
| CEP55 | centrosomal protein 55kDa |
| CEP85 | centrosomal protein 85kDa |
| CHRNB2 | cholinergic receptor, nicotinic, beta 2 (neuronal) |
| CHST10 | carbohydrate sulfotransferase 10 |
| CHST5 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5 |
| CRY1 | cryptochrome circadian clock 1 |
| DCLRE1B | DNA cross-link repair 1B |
| DCTN4 | dynactin 4 (p62) |
| DDB2 | damage-specific DNA binding protein 2, 48kDa |
| DHRS7B | dehydrogenase/reductase (SDR family) member 7B |
| DNAJB14 | DnaJ (Hsp40) homolog, subfamily B, member 14 |
| FAM160B2 | family with sequence similarity 160, member B2 |
| FASTKD5 | FAST kinase domains 5 |
| FCHSD2 | FCH and double SH3 domains 2 |
| FYCO1 | FYVE and coiled-coil domain containing 1 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 |
| GCHFR | GTP cyclohydrolase I feedback regulator |
| GMCL1 | germ cell-less, spermatogenesis associated 1 |
| HIST1H1E | histone cluster 1, H1e |
| HRAS | Harvey rat sarcoma viral oncogene homolog |
| IFITM2 | interferon induced transmembrane protein 2 |
| IFITM3 | interferon induced transmembrane protein 3 |
| IFNA17 | interferon, alpha 17 |
| ILKAP | integrin-linked kinase-associated serine/threonine phosphatase |
| ITGA10 | integrin, alpha 10 |
| JMJD1C | jumonji domain containing 1C |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 |
| KIAA0753 | KIAA0753 |
| KPTN | kaptin (actin binding protein) |
| LOC642236 | FSHD region gene 1 pseudogene |
| LRRC8D | leucine rich repeat containing 8 family, member D |
| MAP7D1 | MAP7 domain containing 1 |
| MAPK12 | mitogen-activated protein kinase 12 |
| MGA | MGA, MAX dimerization protein |
| MID1IP1 | MID1 interacting protein 1 |
| MIS12 | MIS12 kinetochore complex component |
| MXRA7 | matrix-remodelling associated 7 |
| MXRA8 | matrix-remodelling associated 8 |
| NOC2L | nucleolar complex associated 2 homolog (S. cerevisiae) |
| OCEL1 | occludin/ELL domain containing 1 |
| P2RX4 | purinergic receptor P2X, ligand gated ion channel, 4 |
| PAFAH1B3 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) |
| PDSS2 | prenyl (decaprenyl) diphosphate synthase, subunit 2 |
| PEPD | peptidase D |
| PEX12 | peroxisomal biogenesis factor 12 |
| PEX26 | peroxisomal biogenesis factor 26 |
| PHKG2 | phosphorylase kinase, gamma 2 (testis) |
| PIGK | phosphatidylinositol glycan anchor biosynthesis, class K |
| PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta |
| PLXNA1 | plexin A1 |
| PMM2 | phosphomannomutase 2 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) |
| RECQL4 | RecQ protein-like 4 |
| RNF144A | ring finger protein 144A |
| SETD1B | SET domain containing 1B |
| SGTA | small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha |
| SIRT6 | sirtuin 6 |
| SKI | SKI proto-oncogene |
| SLC25A22 | solute carrier family 25 (mitochondrial carrier: glutamate), member 22 |
| SLC25A40 | solute carrier family 25, member 40 |
| SMU1 | smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans) |
| SNX6 | sorting nexin 6 |
| SP3 | Sp3 transcription factor |
| SRBD1 | S1 RNA binding domain 1 |
| STAC | SH3 and cysteine rich domain |
| STXBP2 | syntaxin binding protein 2 |
| TAC3 | tachykinin 3 |
| THG1L | tRNA-histidine guanylyltransferase 1-like (S. cerevisiae) |
| TIPIN | TIMELESS interacting protein |
| TRAC | T cell receptor alpha constant |
| TRAM2 | translocation associated membrane protein 2 |
| TRIM66 | tripartite motif containing 66 |
| TSLIG2 | tRNA splicing ligase complex subunit 2 |
| TTC17 | tetratricopeptide repeat domain 17 |
| URM1 | ubiquitin related modifier 1 |
| USB1 | U6 snRNA biogenesis 1 |
| UTP11L | UTP11-like, U3 small nucleolar ribonucleoprotein (yeast) |
| VPS8 | vacuolar protein sorting 8 homolog (S. cerevisiae) |
| XPA | xeroderma pigmentosum, complementation group A |
| ZW10 | zw10 kinetochore protein |
