| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
| Downloads & Tools |
194 genes differentially expressed following the amylocaine-4089 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADAM22 | ADAM metallopeptidase domain 22 |
| ADGRE2 | adhesion G protein-coupled receptor E2 |
| AGER | advanced glycosylation end product-specific receptor |
| AKAP6 | A kinase (PRKA) anchor protein 6 |
| AKR1D1 | aldo-keto reductase family 1, member D1 |
| ALDH6A1 | aldehyde dehydrogenase 6 family, member A1 |
| ALOX5 | arachidonate 5-lipoxygenase |
| ANKRD2 | ankyrin repeat domain 2 (stretch responsive muscle) |
| APOBEC3G | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G |
| APOC4 | apolipoprotein C-IV |
| ATN1 | atrophin 1 |
| ATXN8OS | ATXN8 opposite strand (non-protein coding) |
| BLZF1 | basic leucine zipper nuclear factor 1 |
| C17ORF59 | chromosome 17 open reading frame 59 |
| C19ORF57 | chromosome 19 open reading frame 57 |
| C2CD2L | C2CD2-like |
| CA9 | carbonic anhydrase IX |
| CACNB1 | calcium channel, voltage-dependent, beta 1 subunit |
| CADM3 | cell adhesion molecule 3 |
| CAMK2B | calcium/calmodulin-dependent protein kinase II beta |
| CCL2 | chemokine (C-C motif) ligand 2 |
| CD22 | CD22 molecule |
| CD6 | CD6 molecule |
| CD79A | CD79a molecule, immunoglobulin-associated alpha |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 |
| CFAP43 | cilia and flagella associated protein 43 |
| CHRNA6 | cholinergic receptor, nicotinic, alpha 6 (neuronal) |
| CLCA2 | chloride channel accessory 2 |
| COMMD4 | COMM domain containing 4 |
| CSF1R | colony stimulating factor 1 receptor |
| CYP2J2 | cytochrome P450, family 2, subfamily J, polypeptide 2 |
| DNAJC28 | DnaJ (Hsp40) homolog, subfamily C, member 28 |
| DNASE2B | deoxyribonuclease II beta |
| DPF1 | D4, zinc and double PHD fingers family 1 |
| DUSP1 | dual specificity phosphatase 1 |
| DUX4L8 | double homeobox 4 like 8 |
| EBF2 | early B-cell factor 2 |
| ESR1 | estrogen receptor 1 |
| F12 | coagulation factor XII (Hageman factor) |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 |
| GJA8 | gap junction protein, alpha 8, 50kDa |
| GK2 | glycerol kinase 2 |
| GPR17 | G protein-coupled receptor 17 |
| GRIK1 | glutamate receptor, ionotropic, kainate 1 |
| HAS1 | hyaluronan synthase 1 |
| HGD | homogentisate 1,2-dioxygenase |
| HOXC11 | homeobox C11 |
| HOXD10 | homeobox D10 |
| HTR1B | 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled |
| HTR4 | 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled |
| IFNA14 | interferon, alpha 14 |
| IGSF6 | immunoglobulin superfamily, member 6 |
| IHH | indian hedgehog |
| KCNAB1 | potassium channel, voltage gated subfamily A regulatory beta subunit 1 |
| KCND3 | potassium channel, voltage gated Shal related subfamily D, member 3 |
| KCNJ5 | potassium channel, inwardly rectifying subfamily J, member 5 |
| KCNK12 | potassium channel, two pore domain subfamily K, member 12 |
| KEL | Kell blood group, metallo-endopeptidase |
| KERA | keratocan |
| KIF1C | kinesin family member 1C |
| KNG1 | kininogen 1 |
| LCAT | lecithin-cholesterol acyltransferase |
| LOC79999 | uncharacterized LOC79999 |
| LRRC48 | leucine rich repeat containing 48 |
| MAB21L1 | mab-21-like 1 (C. elegans) |
| MAN2A2 | mannosidase, alpha, class 2A, member 2 |
| MLLT4 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 |
| MTHFR | methylenetetrahydrofolate reductase (NAD(P)H) |
| MYF5 | myogenic factor 5 |
| N4BP2L1 | NEDD4 binding protein 2-like 1 |
| NOP14-AS1 | NOP14 antisense RNA 1 |
| OAZ3 | ornithine decarboxylase antizyme 3 |
| ONECUT2 | one cut homeobox 2 |
| PCDHA9 | protocadherin alpha 9 |
| PDE12 | phosphodiesterase 12 |
| PDE4B | phosphodiesterase 4B, cAMP-specific |
| PER1 | period circadian clock 1 |
| PHF8 | PHD finger protein 8 |
| PMFBP1 | polyamine modulated factor 1 binding protein 1 |
| PPP1R2P9 | protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 9 |
| PRAF2 | PRA1 domain family, member 2 |
| PRB3 | proline-rich protein BstNI subfamily 3 |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) |
| PTGER3 | prostaglandin E receptor 3 (subtype EP3) |
| RAPGEFL1 | Rap guanine nucleotide exchange factor (GEF)-like 1 |
| RIN3 | Ras and Rab interactor 3 |
| SARM1 | sterile alpha and TIR motif containing 1 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit |
| SIGLEC6 | sialic acid binding Ig-like lectin 6 |
| SLC12A4 | solute carrier family 12 (potassium/chloride transporter), member 4 |
| SYT5 | synaptotagmin V |
| TLR2 | toll-like receptor 2 |
| TPPP | tubulin polymerization promoting protein |
| TRIM10 | tripartite motif containing 10 |
| TRIM3 | tripartite motif containing 3 |
| ZMIZ2 | zinc finger, MIZ-type containing 2 |
| Symbol | Name |
|---|---|
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 |
| AMT | aminomethyltransferase |
| ANP32A-IT1 | ANP32A intronic transcript 1 |
| ARL14 | ADP-ribosylation factor-like 14 |
| ARSB | arylsulfatase B |
| ASTN1 | astrotactin 1 |
| ATAT1 | alpha tubulin acetyltransferase 1 |
| BGLAP | bone gamma-carboxyglutamate (gla) protein |
| BMP10 | bone morphogenetic protein 10 |
| C3AR1 | complement component 3a receptor 1 |
| CD82 | CD82 molecule |
| CGA | glycoprotein hormones, alpha polypeptide |
| CLIC3 | chloride intracellular channel 3 |
| CLN6 | ceroid-lipofuscinosis, neuronal 6, late infantile, variant |
| CNN1 | calponin 1, basic, smooth muscle |
| CNNM4 | cyclin and CBS domain divalent metal cation transport mediator 4 |
| CNTFR | ciliary neurotrophic factor receptor |
| CPEB1 | cytoplasmic polyadenylation element binding protein 1 |
| CTC1 | CTS telomere maintenance complex component 1 |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| DNMBP | dynamin binding protein |
| DUSP8 | dual specificity phosphatase 8 |
| EFNA3 | ephrin-A3 |
| ETNK2 | ethanolamine kinase 2 |
| FOXA1 | forkhead box A1 |
| GALNS | galactosamine (N-acetyl)-6-sulfatase |
| GAS8 | growth arrest-specific 8 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 |
| GNA14 | guanine nucleotide binding protein (G protein), alpha 14 |
| GNL1 | guanine nucleotide binding protein-like 1 |
| GPC3 | glypican 3 |
| GTF3C5 | general transcription factor IIIC, polypeptide 5, 63kDa |
| HOOK1 | hook microtubule-tethering protein 1 |
| HOXA4 | homeobox A4 |
| IBA57 | IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae) |
| IL17RB | interleukin 17 receptor B |
| JAM3 | junctional adhesion molecule 3 |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| LMO7 | LIM domain 7 |
| LPPR4 | lipid phosphate phosphatase-related protein type 4 |
| LYPD1 | LY6/PLAUR domain containing 1 |
| LYPD3 | LY6/PLAUR domain containing 3 |
| MCOLN1 | mucolipin 1 |
| MGP | matrix Gla protein |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 |
| MON1B | MON1 secretory trafficking family member B |
| MPP3 | membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) |
| NECAB3 | N-terminal EF-hand calcium binding protein 3 |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NKX3-2 | NK3 homeobox 2 |
| NR3C2 | nuclear receptor subfamily 3, group C, member 2 |
| NTSR1 | neurotensin receptor 1 (high affinity) |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
| PADI1 | peptidyl arginine deiminase, type I |
| PALMD | palmdelphin |
| PAX9 | paired box 9 |
| PCDH12 | protocadherin 12 |
| PCDHA5 | protocadherin alpha 5 |
| PIGZ | phosphatidylinositol glycan anchor biosynthesis, class Z |
| PLAC8 | placenta-specific 8 |
| PLCD1 | phospholipase C, delta 1 |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| PLEKHG6 | pleckstrin homology domain containing, family G (with RhoGef domain) member 6 |
| PPP2R1A | protein phosphatase 2, regulatory subunit A, alpha |
| PRSS22 | protease, serine, 22 |
| PTGFR | prostaglandin F receptor (FP) |
| PVRL2 | poliovirus receptor-related 2 (herpesvirus entry mediator B) |
| PXMP4 | peroxisomal membrane protein 4, 24kDa |
| QPCTL | glutaminyl-peptide cyclotransferase-like |
| RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 |
| RHPN1-AS1 | RHPN1 antisense RNA 1 (head to head) |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase |
| SCN8A | sodium channel, voltage gated, type VIII alpha subunit |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 |
| SMARCD3 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 |
| SSTR4 | somatostatin receptor 4 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 |
| STARD5 | StAR-related lipid transfer (START) domain containing 5 |
| STEAP4 | STEAP family member 4 |
| TAB1 | TGF-beta activated kinase 1/MAP3K7 binding protein 1 |
| TBC1D8B | TBC1 domain family, member 8B (with GRAM domain) |
| TM7SF2 | transmembrane 7 superfamily member 2 |
| TMEM2 | transmembrane protein 2 |
| TNFSF15 | tumor necrosis factor (ligand) superfamily, member 15 |
| TSC22D4 | TSC22 domain family, member 4 |
| TSPAN1 | tetraspanin 1 |
| WBP2 | WW domain binding protein 2 |
| ZBTB44 | zinc finger and BTB domain containing 44 |
| ZNF268 | zinc finger protein 268 |
| ZNF408 | zinc finger protein 408 |
| ZNF446 | zinc finger protein 446 |
| ZNF611 | zinc finger protein 611 |
| ZNF747 | zinc finger protein 747 |
| ZNF749 | zinc finger protein 749 |
| ZNF778 | zinc finger protein 778 |
| ZW10 | zw10 kinetochore protein |
