amyloid beta deposits Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description formation of self-assembled aggregates of the cleaved App Abeta protein fragment; often seen in neurodegenerative disorders such as Alzheimer's disease (Mammalian Phenotype Ontology, MP_0003329)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0003329
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Genes

12 gene mutations causing the amyloid beta deposits phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
APOE apolipoprotein E
APP amyloid beta (A4) precursor protein
CAV1 caveolin 1, caveolae protein, 22kDa
CFH complement factor H
CSF1 colony stimulating factor 1 (macrophage)
IDE insulin-degrading enzyme
LDLR low density lipoprotein receptor
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PSAP prosaposin
SORCS1 sortilin-related VPS10 domain containing receptor 1
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
TRIB2 tribbles pseudokinase 2
Funding