amyotrophic lateral sclerosis Gene Set

Dataset HPO Gene-Disease Associations
Category disease or phenotype associations
Type phenotype
Description A motor neuron disease that is characterized by muscle spasticity, rapidly progressive weakness due to muscle atrophy, difficulty in speaking, swallowing, and breathing. (Human Disease Ontology, DOID_332)
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9 genes associated with the amyotrophic lateral sclerosis phenotype by mapping known disease genes to disease phenotypes from the HPO Gene-Disease Associations dataset.

Symbol Name
ALS2 amyotrophic lateral sclerosis 2 (juvenile)
C9ORF72 chromosome 9 open reading frame 72
FIG4 FIG4 phosphoinositide 5-phosphatase
MAPT microtubule-associated protein tau
MATR3 matrin 3
PFN1 profilin 1
PSEN1 presenilin 1
SETX senataxin
UBQLN2 ubiquilin 2