Leukoplakia is a precancerous dermatosis of mucous membranes analogous Leukoplakia is basically a chronic inflammatory hypertrophy in which anaplasia and malignant dyskeratosis may develop and subsequently advance to an invasive squamous cell cancer. The clinical diagnosis of primary anal leukoplakia is indicated by single or multiple slightly raised,irregular, marginated, grayish-white keratinized' patches in the anal canal. Tissue biopsy is necessary for confirmation. (Human Phenotype Ontology, HP_0005212)
1 genes associated with the anal mucosal leukoplakia phenotype by mapping known disease genes to disease phenotypes from the HPO Gene-Disease Associations dataset.
