anaphase-promoting complex Gene Set
Dataset
GO Cellular Component Annotations 2015
Category
structural or functional annotations
Type
cellular component
Description
A ubiquitin ligase complex that degrades mitotic cyclins and anaphase inhibitory protein, thereby triggering sister chromatid separation and exit from mitosis. Substrate recognition by APC occurs through degradation signals, the most common of which is termed the Dbox degradation motif, originally discovered in cyclin B. (Gene Ontology , GO_0005680 )
External Link
http://amigo.geneontology.org/amigo/term/GO:0005680
Similar Terms
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Genes
21 proteins localized to the anaphase-promoting complex cellular component from the curated GO Cellular Component Annotations 2015 dataset.
Symbol
Name
ANAPC1
anaphase promoting complex subunit 1
ANAPC10
anaphase promoting complex subunit 10
ANAPC11
anaphase promoting complex subunit 11
ANAPC13
anaphase promoting complex subunit 13
ANAPC15
anaphase promoting complex subunit 15
ANAPC16
anaphase promoting complex subunit 16
ANAPC2
anaphase promoting complex subunit 2
ANAPC4
anaphase promoting complex subunit 4
ANAPC5
anaphase promoting complex subunit 5
ANAPC7
anaphase promoting complex subunit 7
BUB1B
BUB1 mitotic checkpoint serine/threonine kinase B
CDC16
cell division cycle 16
CDC20
cell division cycle 20
CDC23
cell division cycle 23
CDC26
cell division cycle 26
CDC27
cell division cycle 27
CUL7
cullin 7
FZR1
fizzy/cell division cycle 20 related 1 (Drosophila)
MAD2L2
MAD2 mitotic arrest deficient-like 2 (yeast)
UBE2C
ubiquitin-conjugating enzyme E2C
UBE2S
ubiquitin-conjugating enzyme E2S
