androsterone-1296 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the androsterone-1296 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
APOC1 apolipoprotein C-I
ARMC9 armadillo repeat containing 9
BBS9 Bardet-Biedl syndrome 9
BMP1 bone morphogenetic protein 1
BMP15 bone morphogenetic protein 15
BPHL biphenyl hydrolase-like (serine hydrolase)
C1ORF56 chromosome 1 open reading frame 56
CABP2 calcium binding protein 2
CASP10 caspase 10, apoptosis-related cysteine peptidase
CASP2 caspase 2, apoptosis-related cysteine peptidase
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CD59 CD59 molecule, complement regulatory protein
CEP295 centrosomal protein 295kDa
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DGKI diacylglycerol kinase, iota
EIF1 eukaryotic translation initiation factor 1
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
EPHB6 EPH receptor B6
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
FBXO41 F-box protein 41
FGGY FGGY carbohydrate kinase domain containing
FLOT1 flotillin 1
FST follistatin
G0S2 G0/G1 switch 2
GFPT1 glutamine--fructose-6-phosphate transaminase 1
GPR137 G protein-coupled receptor 137
GPR19 G protein-coupled receptor 19
INA internexin neuronal intermediate filament protein, alpha
INPP5B inositol polyphosphate-5-phosphatase, 75kDa
IQCK IQ motif containing K
ITFG2 integrin alpha FG-GAP repeat containing 2
ITM2B integral membrane protein 2B
KYNU kynureninase
LOC157562 uncharacterized LOC157562
LPCAT4 lysophosphatidylcholine acyltransferase 4
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)
MAPK8 mitogen-activated protein kinase 8
MCL1 myeloid cell leukemia 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MED16 mediator complex subunit 16
MED25 mediator complex subunit 25
MGAT2 mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
MLH3 mutL homolog 3
N6AMT1 N-6 adenine-specific DNA methyltransferase 1 (putative)
NUMA1 nuclear mitotic apparatus protein 1
OASL 2'-5'-oligoadenylate synthetase-like
OLAH oleoyl-ACP hydrolase
OSBPL2 oxysterol binding protein-like 2
PDE4DIP phosphodiesterase 4D interacting protein
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma
PRAMEF11 PRAME family member 11
PRDM1 PR domain containing 1, with ZNF domain
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit
PSD3 pleckstrin and Sec7 domain containing 3
PTAFR platelet-activating factor receptor
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTN pleiotrophin
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
RAB6A RAB6A, member RAS oncogene family
RBMS2 RNA binding motif, single stranded interacting protein 2
RHOD ras homolog family member D
RPS6KA6 ribosomal protein S6 kinase, 90kDa, polypeptide 6
RRN3P1 RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1
RRP1B ribosomal RNA processing 1B
RUFY3 RUN and FYVE domain containing 3
SCAND2P SCAN domain containing 2 pseudogene
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SGSM2 small G protein signaling modulator 2
SIL1 SIL1 nucleotide exchange factor
SIN3B SIN3 transcription regulator family member B
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SLCO1C1 solute carrier organic anion transporter family, member 1C1
SMG6 SMG6 nonsense mediated mRNA decay factor
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
SNAPC5 small nuclear RNA activating complex, polypeptide 5, 19kDa
SPTB spectrin, beta, erythrocytic
STARD5 StAR-related lipid transfer (START) domain containing 5
SV2A synaptic vesicle glycoprotein 2A
TIAM1 T-cell lymphoma invasion and metastasis 1
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast)
TLE4 transducin-like enhancer of split 4
TMC7 transmembrane channel-like 7
TOE1 target of EGR1, member 1 (nuclear)
TSC22D2 TSC22 domain family, member 2
ULBP2 UL16 binding protein 2
ZBTB7C zinc finger and BTB domain containing 7C
ZNF174 zinc finger protein 174
ZNF423 zinc finger protein 423
ZNF444 zinc finger protein 444
ZNF493 zinc finger protein 493
ZNF675 zinc finger protein 675
ZNF747 zinc finger protein 747
ZNF85 zinc finger protein 85
ZNF862 zinc finger protein 862

decreased expression

Symbol Name
AIM2 absent in melanoma 2
ANAPC2 anaphase promoting complex subunit 2
ANKRD36 ankyrin repeat domain 36
ARMC6 armadillo repeat containing 6
ATAD3A ATPase family, AAA domain containing 3A
ATP6V1H ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
BBC3 BCL2 binding component 3
BBS7 Bardet-Biedl syndrome 7
BRMS1 breast cancer metastasis suppressor 1
BRPF1 bromodomain and PHD finger containing, 1
C11ORF95 chromosome 11 open reading frame 95
C4ORF29 chromosome 4 open reading frame 29
CAPN15 calpain 15
CD3D CD3d molecule, delta (CD3-TCR complex)
CD82 CD82 molecule
CEP131 centrosomal protein 131kDa
CISH cytokine inducible SH2-containing protein
CLSPN claspin
CSF3R colony stimulating factor 3 receptor (granulocyte)
CST3 cystatin C
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
CYB5R1 cytochrome b5 reductase 1
DAAM1 dishevelled associated activator of morphogenesis 1
DOK2 docking protein 2, 56kDa
DYM dymeclin
ECH1 enoyl CoA hydratase 1, peroxisomal
ERAP2 endoplasmic reticulum aminopeptidase 2
GFI1 growth factor independent 1 transcription repressor
GJA1 gap junction protein, alpha 1, 43kDa
GPSM3 G-protein signaling modulator 3
GSTM3 glutathione S-transferase mu 3 (brain)
HELZ helicase with zinc finger
HRAS Harvey rat sarcoma viral oncogene homolog
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
ITGB7 integrin, beta 7
KIAA0753 KIAA0753
KPTN kaptin (actin binding protein)
LAMP5 lysosomal-associated membrane protein family, member 5
LIN37 lin-37 DREAM MuvB core complex component
LMNB2 lamin B2
LSP1 lymphocyte-specific protein 1
MAGOHB mago-nashi homolog B (Drosophila)
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2
MAPK12 mitogen-activated protein kinase 12
MBTD1 mbt domain containing 1
MEN1 multiple endocrine neoplasia I
METTL8 methyltransferase like 8
MFSD11 major facilitator superfamily domain containing 11
MGMT O-6-methylguanine-DNA methyltransferase
MRGBP MRG/MORF4L binding protein
MRPL2 mitochondrial ribosomal protein L2
MXD3 MAX dimerization protein 3
MYBBP1A MYB binding protein (P160) 1a
NEU1 sialidase 1 (lysosomal sialidase)
NPLOC4 nuclear protein localization 4 homolog (S. cerevisiae)
NRGN neurogranin (protein kinase C substrate, RC3)
NUCB1 nucleobindin 1
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1
PAGR1 PAXIP1 associated glutamate-rich protein 1
PAM16 presequence translocase-associated motor 16 homolog (S. cerevisiae)
PCID2 PCI domain containing 2
PES1 pescadillo ribosomal biogenesis factor 1
PKN1 protein kinase N1
PLEKHJ1 pleckstrin homology domain containing, family J member 1
PMVK phosphomevalonate kinase
PNPLA6 patatin-like phospholipase domain containing 6
POMGNT1 protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-)
POP1 processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae)
PTCD2 pentatricopeptide repeat domain 2
RAB17 RAB17, member RAS oncogene family
RAB8B RAB8B, member RAS oncogene family
RAD54L2 RAD54-like 2 (S. cerevisiae)
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RBM42 RNA binding motif protein 42
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RPL23AP7 ribosomal protein L23a pseudogene 7
SARS2 seryl-tRNA synthetase 2, mitochondrial
SCRIB scribbled planar cell polarity protein
SHARPIN SHANK-associated RH domain interactor
SKA1 spindle and kinetochore associated complex subunit 1
SLC39A7 solute carrier family 39 (zinc transporter), member 7
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SRD5A3 steroid 5 alpha-reductase 3
STBD1 starch binding domain 1
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
TMEM183A transmembrane protein 183A
TPRA1 transmembrane protein, adipocyte asscociated 1
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
TSSC4 tumor suppressing subtransferable candidate 4
U2AF1 U2 small nuclear RNA auxiliary factor 1
UBQLN4 ubiquilin 4
UBXN6 UBX domain protein 6
VAT1 vesicle amine transport 1
WT1-AS WT1 antisense RNA
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
ZNF557 zinc finger protein 557
ZNF721 zinc finger protein 721
ZNF787 zinc finger protein 787