androsterone-5696 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

200 genes differentially expressed following the androsterone-5696 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADGRF5 adhesion G protein-coupled receptor F5
ADGRL3 adhesion G protein-coupled receptor L3
APOE apolipoprotein E
AQP3 aquaporin 3 (Gill blood group)
ATF5 activating transcription factor 5
ATN1 atrophin 1
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
BARX1 BARX homeobox 1
BDNF brain-derived neurotrophic factor
BICC1 BicC family RNA binding protein 1
BTNL3 butyrophilin-like 3
CACNG1 calcium channel, voltage-dependent, gamma subunit 1
CATSPERB catsper channel auxiliary subunit beta
CC2D1A coiled-coil and C2 domain containing 1A
CCDC30 coiled-coil domain containing 30
CD1C CD1c molecule
CDKL1 cyclin-dependent kinase-like 1 (CDC2-related kinase)
CLTC clathrin, heavy chain (Hc)
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CRP C-reactive protein, pentraxin-related
CST1 cystatin SN
CTSS cathepsin S
CXCR4 chemokine (C-X-C motif) receptor 4
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11
CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12
DCLK2 doublecortin-like kinase 2
DCT dopachrome tautomerase
DSCAM Down syndrome cell adhesion molecule
DUSP6 dual specificity phosphatase 6
EFR3B EFR3 homolog B (S. cerevisiae)
EGFR epidermal growth factor receptor
ELSPBP1 epididymal sperm binding protein 1
ESR1 estrogen receptor 1
EVI2B ecotropic viral integration site 2B
FGD1 FYVE, RhoGEF and PH domain containing 1
FGF16 fibroblast growth factor 16
FPR1 formyl peptide receptor 1
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
GADD45G growth arrest and DNA-damage-inducible, gamma
GALR3 galanin receptor 3
GAP43 growth associated protein 43
GPR21 G protein-coupled receptor 21
GPRC5D G protein-coupled receptor, class C, group 5, member D
GRPR gastrin-releasing peptide receptor
GSTM5 glutathione S-transferase mu 5
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KLK13 kallikrein-related peptidase 13
KLRB1 killer cell lectin-like receptor subfamily B, member 1
LEFTY2 left-right determination factor 2
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LINC01587 long intergenic non-protein coding RNA 1587
LPAR4 lysophosphatidic acid receptor 4
LRRC75B leucine rich repeat containing 75B
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
MCAM melanoma cell adhesion molecule
METTL7A methyltransferase like 7A
MS4A1 membrane-spanning 4-domains, subfamily A, member 1
MTMR8 myotubularin related protein 8
MYBPC3 myosin binding protein C, cardiac
MYCL v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog
MYO9B myosin IXB
NDUFA2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NKX6-1 NK6 homeobox 1
NR4A2 nuclear receptor subfamily 4, group A, member 2
NR5A1 nuclear receptor subfamily 5, group A, member 1
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
OR2F2 olfactory receptor, family 2, subfamily F, member 2
OVOL1 ovo-like zinc finger 1
P2RY1 purinergic receptor P2Y, G-protein coupled, 1
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PCDHB17P protocadherin beta 17 pseudogene
PDE4D phosphodiesterase 4D, cAMP-specific
PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
PKD2L2 polycystic kidney disease 2-like 2
PLA2G5 phospholipase A2, group V
PRDM1 PR domain containing 1, with ZNF domain
PSG5 pregnancy specific beta-1-glycoprotein 5
PTGER3 prostaglandin E receptor 3 (subtype EP3)
PTX3 pentraxin 3, long
PXN paxillin
RASSF2 Ras association (RalGDS/AF-6) domain family member 2
RUNX2 runt-related transcription factor 2
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SORCS3 sortilin-related VPS10 domain containing receptor 3
SPARCL1 SPARC-like 1 (hevin)
SPOCK3 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TCL6 T-cell leukemia/lymphoma 6 (non-protein coding)
TEX15 testis expressed 15
TMEM242 transmembrane protein 242
TONSL tonsoku-like, DNA repair protein
TRIB2 tribbles pseudokinase 2
UBE3A ubiquitin protein ligase E3A
UBXN1 UBX domain protein 1
UPK3A uroplakin 3A
ZNF287 zinc finger protein 287

decreased expression

Symbol Name
ADCY6 adenylate cyclase 6
ALS2CL ALS2 C-terminal like
AP3M2 adaptor-related protein complex 3, mu 2 subunit
APOD apolipoprotein D
ARRB1 arrestin, beta 1
ASPHD1 aspartate beta-hydroxylase domain containing 1
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
ATF7IP2 activating transcription factor 7 interacting protein 2
BCL9 B-cell CLL/lymphoma 9
BIK BCL2-interacting killer (apoptosis-inducing)
BMP15 bone morphogenetic protein 15
C17ORF80 chromosome 17 open reading frame 80
CASP3 caspase 3, apoptosis-related cysteine peptidase
CEP85 centrosomal protein 85kDa
CFD complement factor D (adipsin)
CGA glycoprotein hormones, alpha polypeptide
CIR1 corepressor interacting with RBPJ, 1
CLGN calmegin
CRYZL1 crystallin, zeta (quinone reductase)-like 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DDIT3 DNA-damage-inducible transcript 3
DEAF1 DEAF1 transcription factor
DGAT1 diacylglycerol O-acyltransferase 1
DOCK1 dedicator of cytokinesis 1
DUSP5 dual specificity phosphatase 5
DZANK1 double zinc ribbon and ankyrin repeat domains 1
FAM186A family with sequence similarity 186, member A
FARP2 FERM, RhoGEF and pleckstrin domain protein 2
FZD4 frizzled class receptor 4
GINS4 GINS complex subunit 4 (Sld5 homolog)
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2
GLI3 GLI family zinc finger 3
GLS2 glutaminase 2 (liver, mitochondrial)
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
JUNB jun B proto-oncogene
KDM5C lysine (K)-specific demethylase 5C
KIAA0556 KIAA0556
KIAA0894 KIAA0894 protein
KLF7 Kruppel-like factor 7 (ubiquitous)
LRP6 low density lipoprotein receptor-related protein 6
LRRC16A leucine rich repeat containing 16A
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
LYPD1 LY6/PLAUR domain containing 1
MBOAT2 membrane bound O-acyltransferase domain containing 2
MBTPS2 membrane-bound transcription factor peptidase, site 2
MDM4 MDM4, p53 regulator
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MTHFSD methenyltetrahydrofolate synthetase domain containing
MYO1D myosin ID
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NKX3-2 NK3 homeobox 2
NXPE3 neurexophilin and PC-esterase domain family, member 3
OLFML2A olfactomedin-like 2A
OSMR oncostatin M receptor
PACS1 phosphofurin acidic cluster sorting protein 1
PCDHB3 protocadherin beta 3
PHACTR4 phosphatase and actin regulator 4
PHC1 polyhomeotic homolog 1 (Drosophila)
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLA2G10 phospholipase A2, group X
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PPM1F protein phosphatase, Mg2+/Mn2+ dependent, 1F
RAD54L2 RAD54-like 2 (S. cerevisiae)
RASA2 RAS p21 protein activator 2
S100A2 S100 calcium binding protein A2
S100A4 S100 calcium binding protein A4
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SETD8 SET domain containing (lysine methyltransferase) 8
SIRT2 sirtuin 2
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC39A7 solute carrier family 39 (zinc transporter), member 7
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SLMO1 slowmo homolog 1 (Drosophila)
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SPINK5 serine peptidase inhibitor, Kazal type 5
SPTLC3 serine palmitoyltransferase, long chain base subunit 3
STAG3L1 stromal antigen 3-like 1 (pseudogene)
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae)
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TARS2 threonyl-tRNA synthetase 2, mitochondrial (putative)
TET3 tet methylcytosine dioxygenase 3
TMEM19 transmembrane protein 19
TOLLIP toll interacting protein
USP36 ubiquitin specific peptidase 36
WDR19 WD repeat domain 19
WDR76 WD repeat domain 76
WWC2 WW and C2 domain containing 2
ZMAT5 zinc finger, matrin-type 5
ZNF134 zinc finger protein 134
ZNF227 zinc finger protein 227
ZNF250 zinc finger protein 250
ZNF350 zinc finger protein 350
ZNF408 zinc finger protein 408
ZNF586 zinc finger protein 586
ZNF747 zinc finger protein 747
ZNF862 zinc finger protein 862