aneuploidy Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description chromosome count is not an exact multiple of the haploid number (Mammalian Phenotype Ontology, MP_0004024)
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Genes

76 genes co-occuring with the biological term aneuploidy in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ADAM12 ADAM metallopeptidase domain 12
APC adenomatous polyposis coli
AURKA aurora kinase A
AURKB aurora kinase B
BCL6 B-cell CLL/lymphoma 6
BCR breakpoint cluster region
BDNF brain-derived neurotrophic factor
BIRC5 baculoviral IAP repeat containing 5
BLNK B-cell linker
BRCA1 breast cancer 1, early onset
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B
BUB3 BUB3 mitotic checkpoint protein
CDK2 cyclin-dependent kinase 2
CDKN2A cyclin-dependent kinase inhibitor 2A
CDT1 chromatin licensing and DNA replication factor 1
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CENPA centromere protein A
CENPH centromere protein H
CHD1L chromodomain helicase DNA binding protein 1-like
CLASP2 cytoplasmic linker associated protein 2
CROCC ciliary rootlet coiled-coil, rootletin
DAPK1 death-associated protein kinase 1
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
EGFR epidermal growth factor receptor
ESPL1 extra spindle pole bodies homolog 1 (S. cerevisiae)
ESR1 estrogen receptor 1
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
GATA6 GATA binding protein 6
HRAS Harvey rat sarcoma viral oncogene homolog
HSF1 heat shock transcription factor 1
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
JAK2 Janus kinase 2
KLK3 kallikrein-related peptidase 3
LCN1 lipocalin 1
LMNA lamin A/C
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast)
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast)
MAD2L1BP MAD2L1 binding protein
MAPRE2 microtubule-associated protein, RP/EB family, member 2
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MET MET proto-oncogene, receptor tyrosine kinase
MKI67 marker of proliferation Ki-67
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
NQO1 NAD(P)H dehydrogenase, quinone 1
NUMB numb homolog (Drosophila)
NUP88 nucleoporin 88kDa
ORC1 origin recognition complex, subunit 1
PEBP1 phosphatidylethanolamine binding protein 1
PGR progesterone receptor
PLK1 polo-like kinase 1
POLL polymerase (DNA directed), lambda
PPARG peroxisome proliferator-activated receptor gamma
PTTG1 pituitary tumor-transforming 1
RANBP1 RAN binding protein 1
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RB1 retinoblastoma 1
RBX1 ring-box 1, E3 ubiquitin protein ligase
SALL4 spalt-like transcription factor 4
SFN stratifin
SPINK7 serine peptidase inhibitor, Kazal type 7 (putative)
STAG2 stromal antigen 2
SYCP3 synaptonemal complex protein 3
TACC3 transforming, acidic coiled-coil containing protein 3
TERT telomerase reverse transcriptase
TLX1 T-cell leukemia homeobox 1
TMTC1 transmembrane and tetratricopeptide repeat containing 1
TMTC2 transmembrane and tetratricopeptide repeat containing 2
TP53 tumor protein p53
TP73 tumor protein p73
TPT1 tumor protein, translationally-controlled 1
TTK TTK protein kinase
UBE2C ubiquitin-conjugating enzyme E2C
USP7 ubiquitin specific peptidase 7 (herpes virus-associated)
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
ZNF365 zinc finger protein 365