angioedema Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores
Category disease or phenotype associations
Type disease
Description condition similar to urticarai but with swelling occuring in a lower layer of the dermis as well as in the subcutis (Experimental Factor Ontology, EFO_0005532)
Similar Terms
Downloads & Tools

Genes

106 genes co-occuring with the disease angioedema in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 3.40861
KNG1 kininogen 1 2.66221
ACE angiotensin I converting enzyme 2.4632
C1S complement component 1, s subcomponent 2.38506
F12 coagulation factor XII (Hageman factor) 2.18978
KLKB1 kallikrein B, plasma (Fletcher factor) 1 2.18659
C1R complement component 1, r subcomponent 1.78218
SERPINA4 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4 1.72137
XPNPEP2 X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound 1.57111
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 1.50535
FOXH1 forkhead box H1 1.25907
MME membrane metallo-endopeptidase 1.23516
PFDN4 prefoldin subunit 4 1.22302
BDKRB2 bradykinin receptor B2 1.18626
PRCP prolylcarboxypeptidase (angiotensinase C) 1.06312
CPN1 carboxypeptidase N, polypeptide 1 1.06312
PLAT plasminogen activator, tissue 1.05051
F11 coagulation factor XI 1.01005
C5AR1 complement component 5a receptor 1 0.988957
HERC1 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 0.963309
COL24A1 collagen, type XXIV, alpha 1 0.963309
C4A complement component 4A (Rodgers blood group) 0.960797
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide 0.949936
C1QBP complement component 1, q subcomponent binding protein 0.932484
TAC1 tachykinin, precursor 1 0.916375
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 0.858134
MASP2 mannan-binding lectin serine peptidase 2 0.857724
DPP4 dipeptidyl-peptidase 4 0.849945
KRT1 keratin 1, type II 0.827409
CEP68 centrosomal protein 68kDa 0.813873
IL5 interleukin 5 0.78066
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 0.773296
MS4A2 membrane-spanning 4-domains, subfamily A, member 2 0.756564
KRTAP10-9 keratin associated protein 10-9 0.735838
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 0.720461
BDKRB1 bradykinin receptor B1 0.711989
IGHM immunoglobulin heavy constant mu 0.677504
NRG1 neuregulin 1 0.67551
MASP1 mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor) 0.668742
FBXL7 F-box and leucine-rich repeat protein 7 0.654067
ABI3BP ABI family, member 3 (NESH) binding protein 0.619051
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.604981
PIGA phosphatidylinositol glycan anchor biosynthesis, class A 0.590169
CYSLTR1 cysteinyl leukotriene receptor 1 0.577327
INA internexin neuronal intermediate filament protein, alpha 0.569552
CFP complement factor properdin 0.564889
CD79A CD79a molecule, immunoglobulin-associated alpha 0.562169
CFI complement factor I 0.556344
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3 0.554015
KCNK6 potassium channel, two pore domain subfamily K, member 6 0.548971
LTC4S leukotriene C4 synthase 0.546256
PLG plasminogen 0.538118
BICC1 BicC family RNA binding protein 1 0.513802
CD63 CD63 molecule 0.491978
APP amyloid beta (A4) precursor protein 0.483985
ALB albumin 0.482844
RLN3 relaxin 3 0.430017
CR1 complement component (3b/4b) receptor 1 (Knops blood group) 0.420266
MBL2 mannose-binding lectin (protein C) 2, soluble 0.404557
C12ORF57 chromosome 12 open reading frame 57 0.368888
F2 coagulation factor II (thrombin) 0.367779
PRKCQ protein kinase C, theta 0.364824
RNASE3 ribonuclease, RNase A family, 3 0.36187
SCARF1 scavenger receptor class F, member 1 0.361502
VIT vitrin 0.341272
REN renin 0.337975
DCLK3 doublecortin-like kinase 3 0.314278
DNPH1 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 0.313189
CRP C-reactive protein, pentraxin-related 0.311739
HNMT histamine N-methyltransferase 0.298371
HRH1 histamine receptor H1 0.29118
CDH5 cadherin 5, type 2 (vascular endothelium) 0.27794
RIMS1 regulating synaptic membrane exocytosis 1 0.275801
F3 coagulation factor III (thromboplastin, tissue factor) 0.272953
RAD51B RAD51 paralog B 0.257358
TBXA2R thromboxane A2 receptor 0.250311
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.238054
CCL17 chemokine (C-C motif) ligand 17 0.231795
CPM carboxypeptidase M 0.227988
CD2BP2 CD2 (cytoplasmic tail) binding protein 2 0.223509
TTC34 tetratricopeptide repeat domain 34 0.218715
IGHE immunoglobulin heavy constant epsilon 0.216332
PGM1 phosphoglucomutase 1 0.214975
SART1 squamous cell carcinoma antigen recognized by T cells 0.210925
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 0.210253
PTGDS prostaglandin D2 synthase 21kDa (brain) 0.200656
LACTB lactamase, beta 0.200331
CMA1 chymase 1, mast cell 0.188938
CPB2 carboxypeptidase B2 (plasma) 0.183248
FCN3 ficolin (collagen/fibrinogen domain containing) 3 0.174881
SH2D1A SH2 domain containing 1A 0.170054
C3 complement component 3 0.164571
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific) 0.162306
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide 0.162109
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide 0.161912
IL2 interleukin 2 0.159838
FCN2 ficolin (collagen/fibrinogen domain containing lectin) 2 0.144213
PGD phosphogluconate dehydrogenase 0.144005
SALL1 spalt-like transcription factor 1 0.14391
PLCH2 phospholipase C, eta 2 0.143892
NLRP12 NLR family, pyrin domain containing 12 0.143882
DOCK8 dedicator of cytokinesis 8 0.143831
CPA6 carboxypeptidase A6 0.143606
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1 0.142477
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 0.141769
F7 coagulation factor VII (serum prothrombin conversion accelerator) 0.141648