angiogenic Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

342 genes co-occuring with the biological term angiogenic in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ACE2 angiotensin I converting enzyme 2
ACKR1 atypical chemokine receptor 1 (Duffy blood group)
ACVRL1 activin A receptor type II-like 1
ADM adrenomedullin
ADORA2A adenosine A2a receptor
ADORA2B adenosine A2b receptor
ADORA3 adenosine A3 receptor
AGER advanced glycosylation end product-specific receptor
AGGF1 angiogenic factor with G patch and FHA domains 1
AGO2 argonaute RISC catalytic component 2
AGTR1 angiotensin II receptor, type 1
AHSG alpha-2-HS-glycoprotein
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKT2 v-akt murine thymoma viral oncogene homolog 2
ALOX12 arachidonate 12-lipoxygenase
AMOT angiomotin
AMOTL2 angiomotin like 2
ANG angiogenin, ribonuclease, RNase A family, 5
ANGPT1 angiopoietin 1
ANGPT2 angiopoietin 2
ANGPT4 angiopoietin 4
ANGPTL4 angiopoietin-like 4
ANPEP alanyl (membrane) aminopeptidase
ANXA1 annexin A1
ANXA3 annexin A3
APLNR apelin receptor
ATF4 activating transcription factor 4
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
ATP6AP2 ATPase, H+ transporting, lysosomal accessory protein 2
AXL AXL receptor tyrosine kinase
BCL2 B-cell CLL/lymphoma 2
BDNF brain-derived neurotrophic factor
BIRC5 baculoviral IAP repeat containing 5
BMP2 bone morphogenetic protein 2
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase)
BMX BMX non-receptor tyrosine kinase
BRCA1 breast cancer 1, early onset
BSG basigin (Ok blood group)
C1QTNF3 C1q and tumor necrosis factor related protein 3
CALCA calcitonin-related polypeptide alpha
CAV1 caveolin 1, caveolae protein, 22kDa
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCL15 chemokine (C-C motif) ligand 15
CCL2 chemokine (C-C motif) ligand 2
CD248 CD248 molecule, endosialin
CD276 CD276 molecule
CD34 CD34 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CD40LG CD40 ligand
CD93 CD93 molecule
CDC25B cell division cycle 25B
CDH5 cadherin 5, type 2 (vascular endothelium)
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CHEK2 checkpoint kinase 2
CHGA chromogranin A
CHUK conserved helix-loop-helix ubiquitous kinase
COL18A1 collagen, type XVIII, alpha 1
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like)
CRP C-reactive protein, pentraxin-related
CRTC2 CREB regulated transcription coactivator 2
CTGF connective tissue growth factor
CTNND1 catenin (cadherin-associated protein), delta 1
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL16 chemokine (C-X-C motif) ligand 16
CXCL5 chemokine (C-X-C motif) ligand 5
CXCL6 chemokine (C-X-C motif) ligand 6
CXCL8 chemokine (C-X-C motif) ligand 8
CXCL9 chemokine (C-X-C motif) ligand 9
CXCR2 chemokine (C-X-C motif) receptor 2
CXCR3 chemokine (C-X-C motif) receptor 3
CXCR4 chemokine (C-X-C motif) receptor 4
CYLD cylindromatosis (turban tumor syndrome)
CYR61 cysteine-rich, angiogenic inducer, 61
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DCLK1 doublecortin-like kinase 1
DCN decorin
DKK1 dickkopf WNT signaling pathway inhibitor 1
DKK3 dickkopf WNT signaling pathway inhibitor 3
DLL4 delta-like 4 (Drosophila)
DPP4 dipeptidyl-peptidase 4
DUSP1 dual specificity phosphatase 1
DYSF dysferlin
EDIL3 EGF-like repeats and discoidin I-like domains 3
EDN1 endothelin 1
EDNRA endothelin receptor type A
EDNRB endothelin receptor type B
EGFR epidermal growth factor receptor
EGLN1 egl-9 family hypoxia-inducible factor 1
EGR1 early growth response 1
EGR3 early growth response 3
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3
EIF4E eukaryotic translation initiation factor 4E
ENG endoglin
EP300 E1A binding protein p300
EPAS1 endothelial PAS domain protein 1
EPHA1 EPH receptor A1
EPO erythropoietin
EPOR erythropoietin receptor
ERBB2 erb-b2 receptor tyrosine kinase 2
ESR1 estrogen receptor 1
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
F2 coagulation factor II (thrombin)
F2R coagulation factor II (thrombin) receptor
F2RL1 coagulation factor II (thrombin) receptor-like 1
F3 coagulation factor III (thromboplastin, tissue factor)
FES FES proto-oncogene, tyrosine kinase
FGF13 fibroblast growth factor 13
FGF2 fibroblast growth factor 2 (basic)
FGFBP1 fibroblast growth factor binding protein 1
FGFR1 fibroblast growth factor receptor 1
FHL2 four and a half LIM domains 2
FIGF c-fos induced growth factor (vascular endothelial growth factor D)
FLT1 fms-related tyrosine kinase 1
FLT4 fms-related tyrosine kinase 4
FOSL1 FOS-like antigen 1
FOXP1 forkhead box P1
GAS6 growth arrest-specific 6
GBP1 guanylate binding protein 1, interferon-inducible
GDF15 growth differentiation factor 15
GHRH growth hormone releasing hormone
GJA1 gap junction protein, alpha 1, 43kDa
GPC1 glypican 1
GPR4 G protein-coupled receptor 4
GREM1 gremlin 1, DAN family BMP antagonist
GRP gastrin-releasing peptide
HBEGF heparin-binding EGF-like growth factor
HDAC5 histone deacetylase 5
HDGF hepatoma-derived growth factor
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HMGB1 high mobility group box 1
HMOX1 heme oxygenase 1
HOXA5 homeobox A5
HPSE heparanase
HRAS Harvey rat sarcoma viral oncogene homolog
HS6ST1 heparan sulfate 6-O-sulfotransferase 1
HS6ST2 heparan sulfate 6-O-sulfotransferase 2
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
HSPA8 heat shock 70kDa protein 8
IBSP integrin-binding sialoprotein
ICAM1 intercellular adhesion molecule 1
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IFNA1 interferon, alpha 1
IFNA2 interferon, alpha 2
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF1R insulin-like growth factor 1 receptor
IL10 interleukin 10
IL18 interleukin 18
IL19 interleukin 19
IL6 interleukin 6
IL6R interleukin 6 receptor
ILK integrin-linked kinase
INS insulin
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
ITGAV integrin, alpha V
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
ITGB5 integrin, beta 5
ITGB8 integrin, beta 8
ITLN1 intelectin 1 (galactofuranose binding)
JAG1 jagged 1
JAK2 Janus kinase 2
JAM3 junctional adhesion molecule 3
JMJD6 jumonji domain containing 6
KDM5B lysine (K)-specific demethylase 5B
KDR kinase insert domain receptor
KITLG KIT ligand
KLF4 Kruppel-like factor 4 (gut)
KNG1 kininogen 1
L1CAM L1 cell adhesion molecule
LEP leptin
LGALS3 lectin, galactoside-binding, soluble, 3
LIMK1 LIM domain kinase 1
LNPEP leucyl/cystinyl aminopeptidase
LVRN laeverin
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MAPK7 mitogen-activated protein kinase 7
MCAM melanoma cell adhesion molecule
MDK midkine (neurite growth-promoting factor 2)
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MEOX2 mesenchyme homeobox 2
MET MET proto-oncogene, receptor tyrosine kinase
MFAP5 microfibrillar associated protein 5
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MIR1-1 microRNA 1-1
MIR10A microRNA 10a
MIR126 microRNA 126
MIR130A microRNA 130a
MIR132 microRNA 132
MIR155 microRNA 155
MIR16-1 microRNA 16-1
MIR17 microRNA 17
MIR182 microRNA 182
MIR19B1 microRNA 19b-1
MIR20A microRNA 20a
MIR21 microRNA 21
MIR27B microRNA 27b
MIR29A microRNA 29a
MIR424 microRNA 424
MIR92A1 microRNA 92a-1
MMP1 matrix metallopeptidase 1
MMP10 matrix metallopeptidase 10
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MMP2 matrix metallopeptidase 2
MMP9 matrix metallopeptidase 9
MST1R macrophage stimulating 1 receptor
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
MYO1C myosin IC
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2)
NAMPT nicotinamide phosphoribosyltransferase
NES nestin
NFE2L2 nuclear factor, erythroid 2-like 2
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NOL7 nucleolar protein 7, 27kDa
NOS1 nitric oxide synthase 1 (neuronal)
NOTCH4 notch 4
NOV nephroblastoma overexpressed
NOX4 NADPH oxidase 4
NR4A1 nuclear receptor subfamily 4, group A, member 1
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
NRP1 neuropilin 1
NRP2 neuropilin 2
NTN1 netrin 1
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
NUCLEOLIN nucleolin multifunctional protein
PARG poly (ADP-ribose) glycohydrolase
PAX2 paired box 2
PCGF2 polycomb group ring finger 2
PDGFA platelet-derived growth factor alpha polypeptide
PDGFC platelet derived growth factor C
PDGFD platelet derived growth factor D
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PECAM1 platelet/endothelial cell adhesion molecule 1
PF4 platelet factor 4
PF4V1 platelet factor 4 variant 1
PGF placental growth factor
PHACTR1 phosphatase and actin regulator 1
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
PLAU plasminogen activator, urokinase
PLAUR plasminogen activator, urokinase receptor
PLCG1 phospholipase C, gamma 1
PLG plasminogen
PLXDC1 plexin domain containing 1
PLXNB1 plexin B1
PPARG peroxisome proliferator-activated receptor gamma
PREX1 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
PRKCA protein kinase C, alpha
PRL prolactin
PROK1 prokineticin 1
PTEN phosphatase and tensin homolog
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PTGIR prostaglandin I2 (prostacyclin) receptor (IP)
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTN pleiotrophin
PTPN23 protein tyrosine phosphatase, non-receptor type 23
PTPRJ protein tyrosine phosphatase, receptor type, J
PTTG1 pituitary tumor-transforming 1
RAB25 RAB25, member RAS oncogene family
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RAP1A RAP1A, member of RAS oncogene family
RAPGEF3 Rap guanine nucleotide exchange factor (GEF) 3
RASA1 RAS p21 protein activator (GTPase activating protein) 1
RCAN1 regulator of calcineurin 1
RNF213 ring finger protein 213
RPL19 ribosomal protein L19
RRAS related RAS viral (r-ras) oncogene homolog
RUNX2 runt-related transcription factor 2
S100A13 S100 calcium binding protein A13
S100A4 S100 calcium binding protein A4
S1PR1 sphingosine-1-phosphate receptor 1
SBSN suprabasin
SDC1 syndecan 1
SELE selectin E
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SHB Src homology 2 domain containing adaptor protein B
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SIRT1 sirtuin 1
SLIT2 slit homolog 2 (Drosophila)
SMAD3 SMAD family member 3
SMOC2 SPARC related modular calcium binding 2
SOCS3 suppressor of cytokine signaling 3
SOD2 superoxide dismutase 2, mitochondrial
SOX11 SRY (sex determining region Y)-box 11
SP1 Sp1 transcription factor
SPP1 secreted phosphoprotein 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
ST14 suppression of tumorigenicity 14 (colon carcinoma)
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT5B signal transducer and activator of transcription 5B
STC1 stanniocalcin 1
STC2 stanniocalcin 2
TAL1 T-cell acute lymphocytic leukemia 1
TARS threonyl-tRNA synthetase
TBXAS1 thromboxane A synthase 1 (platelet)
TEK TEK tyrosine kinase, endothelial
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TGFA transforming growth factor, alpha
TGFB1 transforming growth factor, beta 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
THBS1 thrombospondin 1
TIMP1 TIMP metallopeptidase inhibitor 1
TIMP2 TIMP metallopeptidase inhibitor 2
TIMP3 TIMP metallopeptidase inhibitor 3
TLR2 toll-like receptor 2
TLR3 toll-like receptor 3
TLR4 toll-like receptor 4
TNF tumor necrosis factor
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12
TP53 tumor protein p53
TPSAB1 tryptase alpha/beta 1
TRPC4 transient receptor potential cation channel, subfamily C, member 4
TRPM7 transient receptor potential cation channel, subfamily M, member 7
TSC1 tuberous sclerosis 1
TSHR thyroid stimulating hormone receptor
TSPO translocator protein (18kDa)
TXNDC5 thioredoxin domain containing 5 (endoplasmic reticulum)
TYMP thymidine phosphorylase
UTS2 urotensin 2
VASH1 vasohibin 1
VCAM1 vascular cell adhesion molecule 1
VEGFA vascular endothelial growth factor A
VEGFB vascular endothelial growth factor B
VEGFC vascular endothelial growth factor C
WNT1 wingless-type MMTV integration site family, member 1
WNT2 wingless-type MMTV integration site family member 2
WNT5A wingless-type MMTV integration site family, member 5A
ZC3H12A zinc finger CCCH-type containing 12A
ZEB1 zinc finger E-box binding homeobox 1