angiosarcoma Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores
Category disease or phenotype associations
Type disease
Description A malignant tumor arising from the endothelial cells of the blood vessels. Microscopically, it is characterized by frequently open vascular anastomosing and branching channels. The malignant cells that line the vascular channels are spindle or epithelioid and often display hyperchromatic nuclei. Angiosarcomas most frequently occur in the skin and breast. Patients with long-standing lymphedema are at increased risk of developing angiosarcoma. (Experimental Factor Ontology, EFO_0003968)
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Genes

116 genes co-occuring with the disease angiosarcoma in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
F8 coagulation factor VIII, procoagulant component 2.43668
HBA1 hemoglobin, alpha 1 2.3675
HBA2 hemoglobin, alpha 2 2.34065
CD34 CD34 molecule 2.04371
PROX1 prospero homeobox 1 1.22822
VWF von Willebrand factor 1.13374
IL2 interleukin 2 1.0303
KDR kinase insert domain receptor 0.929587
L1CAM L1 cell adhesion molecule 0.901567
FAM133B family with sequence similarity 133, member B 0.876148
TP53 tumor protein p53 0.869187
FOXO4 forkhead box O4 0.86059
PDPN podoplanin 0.840525
FLT4 fms-related tyrosine kinase 4 0.81059
CD68 CD68 molecule 0.753306
TIE1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 0.732596
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 0.730571
VEGFA vascular endothelial growth factor A 0.716021
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.695905
NUTM2B NUT family member 2B 0.674315
FLT1 fms-related tyrosine kinase 1 0.667152
MYOG myogenin (myogenic factor 4) 0.650903
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 0.630027
APIP APAF1 interacting protein 0.623359
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.618268
KRT7 keratin 7, type II 0.616312
SMARCAD1 SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 0.613965
NUTM2A NUT family member 2A 0.606543
EMCN endomucin 0.591727
CLDN5 claudin 5 0.578883
KCTD12 potassium channel tetramerization domain containing 12 0.55518
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1 0.554015
FGF2 fibroblast growth factor 2 (basic) 0.553239
TLE3 transducin-like enhancer of split 3 0.545868
UBASH3B ubiquitin associated and SH3 domain containing B 0.543542
TEK TEK tyrosine kinase, endothelial 0.542767
CTAG1A cancer/testis antigen 1A 0.540829
SFRP2 secreted frizzled-related protein 2 0.538118
MLANA melan-A 0.52729
CTAG1B cancer/testis antigen 1B 0.526904
VEGFC vascular endothelial growth factor C 0.50459
TGM4 transglutaminase 4 0.500379
LYZ lysozyme 0.486646
MCAM melanoma cell adhesion molecule 0.483985
SLC35G5 solute carrier family 35, member G5 0.471468
KRT20 keratin 20, type I 0.468819
ANGPT4 angiopoietin 4 0.462016
TCL1B T-cell leukemia/lymphoma 1B 0.460506
FSCN3 fascin actin-bundling protein 3, testicular 0.460129
PTPRC protein tyrosine phosphatase, receptor type, C 0.442418
ENG endoglin 0.435275
FSCN2 fascin actin-bundling protein 2, retinal 0.433772
KITLG KIT ligand 0.424765
PIGF phosphatidylinositol glycan anchor biosynthesis, class F 0.42214
CAMTA1 calmodulin binding transcription activator 1 0.41465
CD163 CD163 molecule 0.406051
HRAS Harvey rat sarcoma viral oncogene homolog 0.405678
MB myoglobin 0.401945
MYOD1 myogenic differentiation 1 0.397843
THBD thrombomodulin 0.393374
HOXD3 homeobox D3 0.381852
TG thyroglobulin 0.378885
MIB1 mindbomb E3 ubiquitin protein ligase 1 0.378143
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle) 0.362239
ENO2 enolase 2 (gamma, neuronal) 0.353763
KRT8 keratin 8, type II 0.349349
VMP1 vacuole membrane protein 1 0.348614
PTPRB protein tyrosine phosphatase, receptor type, B 0.346042
LRRC4C leucine rich repeat containing 4C 0.340906
FSCN1 fascin actin-bundling protein 1 0.338707
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.333583
HOXB3 homeobox B3 0.331025
CDH5 cadherin 5, type 2 (vascular endothelium) 0.329565
WT1 Wilms tumor 1 0.316456
CLEC2A C-type lectin domain family 2, member A 0.313189
CLDN2 claudin 2 0.307033
FAM132A family with sequence similarity 132, member A 0.305587
ANKRD1 ankyrin repeat domain 1 (cardiac muscle) 0.290103
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 0.287952
ALPPL2 alkaline phosphatase, placental-like 2 0.28616
F7 coagulation factor VII (serum prothrombin conversion accelerator) 0.285802
ALPP alkaline phosphatase, placental 0.285802
ALPL alkaline phosphatase, liver/bone/kidney 0.285444
ROS1 ROS proto-oncogene 1 , receptor tyrosine kinase 0.283297
ANGPT2 angiopoietin 2 0.282225
SKI SKI proto-oncogene 0.278297
CDKN2A cyclin-dependent kinase inhibitor 2A 0.27687
ANO1 anoctamin 1, calcium activated chloride channel 0.276514
KRT5 keratin 5, type II 0.271174
AFP alpha-fetoprotein 0.266913
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 0.26514
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1 0.263014
NF1 neurofibromin 1 0.261245
WWTR1 WW domain containing transcription regulator 1 0.260891
S1PR1 sphingosine-1-phosphate receptor 1 0.25877
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2) 0.253127
GFAP glial fibrillary acidic protein 0.247852
KRT18 keratin 18, type I 0.242945
SHD Src homology 2 domain containing transforming protein D 0.23666
SHB Src homology 2 domain containing adaptor protein B 0.230063
KRAS Kirsten rat sarcoma viral oncogene homolog 0.229716
RAET1E retinoic acid early transcript 1E 0.201962
PTEN phosphatase and tensin homolog 0.200006
PTK2 protein tyrosine kinase 2 0.185612
MPG N-methylpurine-DNA glycosylase 0.185612
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 0.185313
WASF3 WAS protein family, member 3 0.179239
HAS1 hyaluronan synthase 1 0.176215
FRY furry homolog (Drosophila) 0.169091
ATF1 activating transcription factor 1 0.169091
CCND1 cyclin D1 0.168617
KRT19 keratin 19, type I 0.162707
WDFY2 WD repeat and FYVE domain containing 2 0.162306
TMEM51 transmembrane protein 51 0.160761
HARS histidyl-tRNA synthetase 0.141792
CDK4 cyclin-dependent kinase 4 0.120338