angiosarcoma Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description A malignant tumor arising from the endothelial cells of the blood vessels. Microscopically, it is characterized by frequently open vascular anastomosing and branching channels. The malignant cells that line the vascular channels are spindle or epithelioid and often display hyperchromatic nuclei. Angiosarcomas most frequently occur in the skin and breast. Patients with long-standing lymphedema are at increased risk of developing angiosarcoma. (Experimental Factor Ontology, EFO_0003968)
Similar Terms
Downloads & Tools

Genes

32 genes co-occuring with the biological term angiosarcoma in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
AKT1 v-akt murine thymoma viral oncogene homolog 1
ANXA2 annexin A2
CAMTA1 calmodulin binding transcription activator 1
CCND1 cyclin D1
CLDN5 claudin 5
ENG endoglin
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
FLI1 Fli-1 proto-oncogene, ETS transcription factor
FLT4 fms-related tyrosine kinase 4
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
IL6 interleukin 6
KDR kinase insert domain receptor
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MYC v-myc avian myelocytomatosis viral oncogene homolog
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PDPN podoplanin
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PLCG1 phospholipase C, gamma 1
PROX1 prospero homeobox 1
PTEN phosphatase and tensin homolog
PTPRB protein tyrosine phosphatase, receptor type, B
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RET ret proto-oncogene
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
TLE3 transducin-like enhancer of split 3
TP53 tumor protein p53
TP63 tumor protein p63
VEGFA vascular endothelial growth factor A
WT1 Wilms tumor 1
WWTR1 WW domain containing transcription regulator 1