ankylosis Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores
Category disease or phenotype associations
Type disease
Description Ankylosis is a arthropathy where there is a stiffness of a joint, the result of injury or disease. The rigidity may be complete or partial and may be due to inflammation of the tendinous or muscular structures outside the joint or of the tissues of the joint itself. (Human Disease Ontology, DOID_227)
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Genes

112 genes co-occuring with the disease ankylosis in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
ANKH ANKH inorganic pyrophosphate transport regulator 1.99039
HEBP1 heme binding protein 1 1.67006
BMP2 bone morphogenetic protein 2 1.6642
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 1.66104
NOG noggin 1.49394
GDF5 growth differentiation factor 5 1.41709
ZNF658B zinc finger protein 658B, pseudogene 1.29352
ZNF658 zinc finger protein 658 1.29352
GDF7 growth differentiation factor 7 1.2595
SHOX2 short stature homeobox 2 1.20699
RPF1 ribosome production factor 1 homolog (S. cerevisiae) 1.17121
RUNX2 runt-related transcription factor 2 1.09755
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 1.09083
ALPL alkaline phosphatase, liver/bone/kidney 1.06018
PTH1R parathyroid hormone 1 receptor 1.04125
NOTCH1 notch 1 1.03788
DLX2 distal-less homeobox 2 1.03577
ALPPL2 alkaline phosphatase, placental-like 2 0.986007
ALPP alkaline phosphatase, placental 0.985164
SPP1 secreted phosphoprotein 1 0.941611
MARS2 methionyl-tRNA synthetase 2, mitochondrial 0.922974
SOST sclerostin 0.920498
TRAPPC4 trafficking protein particle complex 4 0.919261
ACVR1 activin A receptor, type I 0.867959
SP7 Sp7 transcription factor 0.86059
MRAP melanocortin 2 receptor accessory protein 0.852811
BGLAP bone gamma-carboxyglutamate (gla) protein 0.847078
PPA1 pyrophosphatase (inorganic) 1 0.829459
IBSP integrin-binding sialoprotein 0.827409
SHOX short stature homeobox 0.815514
FGF2 fibroblast growth factor 2 (basic) 0.811001
FGFR2 fibroblast growth factor receptor 2 0.807718
TNF tumor necrosis factor 0.789672
WNT2B wingless-type MMTV integration site family, member 2B 0.762678
SLC34A1 solute carrier family 34 (type II sodium/phosphate cotransporter), member 1 0.759008
DKK1 dickkopf WNT signaling pathway inhibitor 1 0.759008
PPM1A protein phosphatase, Mg2+/Mn2+ dependent, 1A 0.756156
PLCB4 phospholipase C, beta 4 0.714005
TUFT1 tuftelin 1 0.691896
CEMP1 cementum protein 1 0.682693
STEAP4 STEAP family member 4 0.666755
BMP7 bone morphogenetic protein 7 0.655254
MEPE matrix extracellular phosphoglycoprotein 0.648138
ACAN aggrecan 0.646559
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b 0.643009
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) 0.629242
MGP matrix Gla protein 0.617486
GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 0.61162
BMP4 bone morphogenetic protein 4 0.582384
DLX6 distal-less homeobox 6 0.578106
SLC4A2 solute carrier family 4 (anion exchanger), member 2 0.5645
ENPP3 ectonucleotide pyrophosphatase/phosphodiesterase 3 0.562946
ARNTL aryl hydrocarbon receptor nuclear translocator-like 0.559839
SRCIN1 SRC kinase signaling inhibitor 1 0.551298
FEZF1 FEZ family zinc finger 1 0.517265
LRP6 low density lipoprotein receptor-related protein 6 0.51611
AMIGO2 adhesion molecule with Ig-like domain 2 0.51611
FEZF2 FEZ family zinc finger 2 0.506123
HES1 hes family bHLH transcription factor 1 0.485885
DR1 down-regulator of transcription 1, TBP-binding (negative cofactor 2) 0.479047
SOX9 SRY (sex determining region Y)-box 9 0.47374
CDC7 cell division cycle 7 0.465416
SLC20A2 solute carrier family 20 (phosphate transporter), member 2 0.462016
LEF1 lymphoid enhancer-binding factor 1 0.434148
WNT1 wingless-type MMTV integration site family, member 1 0.429266
PQBP1 polyglutamine binding protein 1 0.418019
IHH indian hedgehog 0.416521
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4 0.387051
WNT5A wingless-type MMTV integration site family, member 5A 0.386308
AAAS achalasia, adrenocortical insufficiency, alacrimia 0.385936
IL2RB interleukin 2 receptor, beta 0.382966
CRP C-reactive protein, pentraxin-related 0.381852
SPTA1 spectrin, alpha, erythrocytic 1 0.38111
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.377773
FN1 fibronectin 1 0.365932
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 0.353027
MATN1 matrilin 1, cartilage matrix protein 0.348614
MEA1 male-enhanced antigen 1 0.348246
COL1A2 collagen, type I, alpha 2 0.346777
DLG3 discs, large homolog 3 (Drosophila) 0.345308
COL10A1 collagen, type X, alpha 1 0.33944
DLX5 distal-less homeobox 5 0.32774
MUL1 mitochondrial E3 ubiquitin protein ligase 1 0.323002
ACPP acid phosphatase, prostate 0.312102
FGFR1 fibroblast growth factor receptor 1 0.304864
PSTPIP1 proline-serine-threonine phosphatase interacting protein 1 0.301615
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) 0.300894
SLC25A20 solute carrier family 25 (carnitine/acylcarnitine translocase), member 20 0.281153
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 0.274376
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 0.255241
ASPN asporin 0.253831
KLK8 kallikrein-related peptidase 8 0.248554
WDR11 WD repeat domain 11 0.240148
ERAP1 endoplasmic reticulum aminopeptidase 1 0.23945
PDGFB platelet-derived growth factor beta polypeptide 0.224884
MCF2 MCF.2 cell line derived transforming sequence 0.221793
MNX1 motor neuron and pancreas homeobox 1 0.218374
DYNLT1 dynein, light chain, Tctex-type 1 0.217352
DSPP dentin sialophosphoprotein 0.209583
NME1 NME/NM23 nucleoside diphosphate kinase 1 0.206248
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11 0.205585
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 0.203604
THRA thyroid hormone receptor, alpha 0.181798
HGD homogentisate 1,2-dioxygenase 0.179239
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator 0.175947
AMPH amphiphysin 0.164571
MSX2 msh homeobox 2 0.164571
AXIN2 axin 2 0.161331
ZMPSTE24 zinc metallopeptidase STE24 0.160574
PRG4 proteoglycan 4 0.159838
MLXIPL MLX interacting protein-like 0.159124
PCNA proliferating cell nuclear antigen 0.157765