antagonist Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

287 genes co-occuring with the biological term antagonist in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ACE angiotensin I converting enzyme
ACO2 aconitase 2, mitochondrial
ADA adenosine deaminase
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary)
ADCYAP1R1 adenylate cyclase activating polypeptide 1 (pituitary) receptor type I
ADIPOQ adiponectin, C1Q and collagen domain containing
ADORA1 adenosine A1 receptor
ADORA2A adenosine A2a receptor
ADRB1 adrenoceptor beta 1
ADRB2 adrenoceptor beta 2, surface
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AGTR1 angiotensin II receptor, type 1
AHR aryl hydrocarbon receptor
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALOX5 arachidonate 5-lipoxygenase
AMH anti-Mullerian hormone
ANGPT1 angiopoietin 1
ANGPT2 angiopoietin 2
APC adenomatous polyposis coli
APP amyloid beta (A4) precursor protein
AR androgen receptor
ARID3A AT rich interactive domain 3A (BRIGHT-like)
ARRB1 arrestin, beta 1
AVPR1A arginine vasopressin receptor 1A
BAK1 BCL2-antagonist/killer 1
BCL2 B-cell CLL/lymphoma 2
BDKRB1 bradykinin receptor B1
BDKRB2 bradykinin receptor B2
BIRC5 baculoviral IAP repeat containing 5
BMP2 bone morphogenetic protein 2
BMP4 bone morphogenetic protein 4
BMP6 bone morphogenetic protein 6
BMP7 bone morphogenetic protein 7
BST2 bone marrow stromal cell antigen 2
C1QTNF3 C1q and tumor necrosis factor related protein 3
C5AR1 complement component 5a receptor 1
C5AR2 complement component 5a receptor 2
CALCA calcitonin-related polypeptide alpha
CBY1 chibby homolog 1 (Drosophila)
CCK cholecystokinin
CCL26 chemokine (C-C motif) ligand 26
CCL7 chemokine (C-C motif) ligand 7
CCL8 chemokine (C-C motif) ligand 8
CCR1 chemokine (C-C motif) receptor 1
CCR2 chemokine (C-C motif) receptor 2
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CCR8 chemokine (C-C motif) receptor 8
CD14 CD14 molecule
CD200 CD200 molecule
CD40LG CD40 ligand
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CHEK1 checkpoint kinase 1
CHRM3 cholinergic receptor, muscarinic 3
CITED4 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4
CNR1 cannabinoid receptor 1 (brain)
CRHR1 corticotropin releasing hormone receptor 1
CRHR2 corticotropin releasing hormone receptor 2
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CST3 cystatin C
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CX3CL1 chemokine (C-X3-C motif) ligand 1
CX3CR1 chemokine (C-X3-C motif) receptor 1
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL11 chemokine (C-X-C motif) ligand 11
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR4 chemokine (C-X-C motif) receptor 4
CYBB cytochrome b-245, beta polypeptide
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
CYP3A cytochrome P450, family 3, subfamily A
CYSLTR1 cysteinyl leukotriene receptor 1
DAND5 DAN domain family member 5, BMP antagonist
DDIT3 DNA-damage-inducible transcript 3
DEFB103B defensin, beta 103B
DKK1 dickkopf WNT signaling pathway inhibitor 1
DKK3 dickkopf WNT signaling pathway inhibitor 3
DKK4 dickkopf WNT signaling pathway inhibitor 4
DNMT1 DNA (cytosine-5-)-methyltransferase 1
DPP4 dipeptidyl-peptidase 4
DRAXIN dorsal inhibitory axon guidance protein
DRD2 dopamine receptor D2
DRD3 dopamine receptor D3
EDN1 endothelin 1
EDNRA endothelin receptor type A
EDNRB endothelin receptor type B
EGFR epidermal growth factor receptor
ELANE elastase, neutrophil expressed
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
F2R coagulation factor II (thrombin) receptor
FBXL19 F-box and leucine-rich repeat protein 19
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
FKBP4 FK506 binding protein 4, 59kDa
FKBP5 FK506 binding protein 5
FLT1 fms-related tyrosine kinase 1
FLT3 fms-related tyrosine kinase 3
FPR2 formyl peptide receptor 2
FRZB frizzled-related protein
FST follistatin
FSTL3 follistatin-like 3 (secreted glycoprotein)
GCGR glucagon receptor
GH1 growth hormone 1
GHR growth hormone receptor
GIP gastric inhibitory polypeptide
GLI2 GLI family zinc finger 2
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
GNRHR gonadotropin-releasing hormone receptor
GREM1 gremlin 1, DAN family BMP antagonist
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B
GTF2B general transcription factor IIB
HACE1 HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1
HCRTR2 hypocretin (orexin) receptor 2
HDAC1 histone deacetylase 1
HFE2 hemochromatosis type 2 (juvenile)
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HHIP hedgehog interacting protein
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HRH1 histamine receptor H1
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
ICAM3 intercellular adhesion molecule 3
IFNAR1 interferon (alpha, beta and omega) receptor 1
IFNB1 interferon, beta 1, fibroblast
IFNG interferon, gamma
IGH immunoglobulin heavy locus
IHH indian hedgehog
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IL10 interleukin 10
IL10RA interleukin 10 receptor, alpha
IL11 interleukin 11
IL13 interleukin 13
IL15RA interleukin 15 receptor, alpha
IL17RC interleukin 17 receptor C
IL17RD interleukin 17 receptor D
IL18 interleukin 18
IL18BP interleukin 18 binding protein
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1F10 interleukin 1 family, member 10 (theta)
IL1R1 interleukin 1 receptor, type I
IL1RN interleukin 1 receptor antagonist
IL20 interleukin 20
IL21 interleukin 21
IL23R interleukin 23 receptor
IL36A interleukin 36, alpha
IL36B interleukin 36, beta
IL36G interleukin 36, gamma
IL36RN interleukin 36 receptor antagonist
IL4 interleukin 4
IL6 interleukin 6
IL6ST interleukin 6 signal transducer
INHA inhibin, alpha
INHBA inhibin, beta A
INHBB inhibin, beta B
INHBC inhibin, beta C
INHBE inhibin, beta E
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
JAK2 Janus kinase 2
JUN jun proto-oncogene
KCNIP3 Kv channel interacting protein 3, calsenilin
KDM1A lysine (K)-specific demethylase 1A
KDR kinase insert domain receptor
KPNA1 karyopherin alpha 1 (importin alpha 5)
LIF leukemia inhibitory factor
LPL lipoprotein lipase
LRP5 low density lipoprotein receptor-related protein 5
LRP6 low density lipoprotein receptor-related protein 6
LY96 lymphocyte antigen 96
MAP2K6 mitogen-activated protein kinase kinase 6
MAP2K7 mitogen-activated protein kinase kinase 7
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MBL2 mannose-binding lectin (protein C) 2, soluble
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MC4R melanocortin 4 receptor
MCHR2 melanin-concentrating hormone receptor 2
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MET MET proto-oncogene, receptor tyrosine kinase
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MIR125B1 microRNA 125b-1
MIR125B2 microRNA 125b-2
MIR199A1 microRNA 199a-1
MIR380 microRNA 380
MMP9 matrix metallopeptidase 9
MPO myeloperoxidase
MSR1 macrophage scavenger receptor 1
MST1R macrophage stimulating 1 receptor
MUC2 mucin 2, oligomeric mucus/gel-forming
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
NCOA2 nuclear receptor coactivator 2
NCOR1 nuclear receptor corepressor 1
NCOR2 nuclear receptor corepressor 2
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NOD1 nucleotide-binding oligomerization domain containing 1
NOD2 nucleotide-binding oligomerization domain containing 2
NOG noggin
NOS3 nitric oxide synthase 3 (endothelial cell)
NOX4 NADPH oxidase 4
NPY2R neuropeptide Y receptor Y2
NR0B1 nuclear receptor subfamily 0, group B, member 1
NR1H4 nuclear receptor subfamily 1, group H, member 4
NR1I2 nuclear receptor subfamily 1, group I, member 2
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NR5A1 nuclear receptor subfamily 5, group A, member 1
NRP1 neuropilin 1
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
OPRK1 opioid receptor, kappa 1
OPRL1 opiate receptor-like 1
OPRM1 opioid receptor, mu 1
OSM oncostatin M
OXER1 oxoeicosanoid (OXE) receptor 1
OXTR oxytocin receptor
P2RX3 purinergic receptor P2X, ligand gated ion channel, 3
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
P2RY1 purinergic receptor P2Y, G-protein coupled, 1
P2RY12 purinergic receptor P2Y, G-protein coupled, 12
P2RY14 purinergic receptor P2Y, G-protein coupled, 14
P2RY4 pyrimidinergic receptor P2Y, G-protein coupled, 4
PDGFB platelet-derived growth factor beta polypeptide
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PDX1 pancreatic and duodenal homeobox 1
PHF20L1 PHD finger protein 20-like 1
PPARA peroxisome proliferator-activated receptor alpha
PPARG peroxisome proliferator-activated receptor gamma
PSD4 pleckstrin and Sec7 domain containing 4
PTAFR platelet-activating factor receptor
PTGES prostaglandin E synthase
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTX3 pentraxin 3, long
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RAMP1 receptor (G protein-coupled) activity modifying protein 1
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RORA RAR-related orphan receptor A
RPS19 ribosomal protein S19
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SELPLG selectin P ligand
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
SFRP1 secreted frizzled-related protein 1
SGPP1 sphingosine-1-phosphate phosphatase 1
SHH sonic hedgehog
SIGMAR1 sigma non-opioid intracellular receptor 1
SLC26A3 solute carrier family 26 (anion exchanger), member 3
SLC26A5 solute carrier family 26 (anion exchanger), member 5
SMO smoothened, frizzled class receptor
SOCS3 suppressor of cytokine signaling 3
SOD2 superoxide dismutase 2, mitochondrial
SOST sclerostin
SOSTDC1 sclerostin domain containing 1
SPIN2B spindlin family, member 2B
STAT1 signal transducer and activator of transcription 1, 91kDa
TACR1 tachykinin receptor 1
TAS2R14 taste receptor, type 2, member 14
TBXA2R thromboxane A2 receptor
TEK TEK tyrosine kinase, endothelial
TGFB1 transforming growth factor, beta 1
TGFB2 transforming growth factor, beta 2
THRB thyroid hormone receptor, beta
TIE1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1
TLR4 toll-like receptor 4
TNF tumor necrosis factor
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TP53 tumor protein p53
TRIB3 tribbles pseudokinase 3
TRPM8 transient receptor potential cation channel, subfamily M, member 8
TRPV1 transient receptor potential cation channel, subfamily V, member 1
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A
VIPR1 vasoactive intestinal peptide receptor 1
VKORC1 vitamin K epoxide reductase complex, subunit 1
VSTM2L V-set and transmembrane domain containing 2 like
VWF von Willebrand factor
WARS tryptophanyl-tRNA synthetase
WDR5 WD repeat domain 5
WIF1 WNT inhibitory factor 1
WNT1 wingless-type MMTV integration site family, member 1
WNT5A wingless-type MMTV integration site family, member 5A
XCR1 chemokine (C motif) receptor 1
ZEB2 zinc finger E-box binding homeobox 2