antazoline-1556 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the antazoline-1556 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAAS achalasia, adrenocortical insufficiency, alacrimia
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ACAN aggrecan
ACVR2A activin A receptor, type IIA
AP1B1 adaptor-related protein complex 1, beta 1 subunit
AXIN1 axin 1
BCKDHB branched chain keto acid dehydrogenase E1, beta polypeptide
CADM3 cell adhesion molecule 3
CAMK1G calcium/calmodulin-dependent protein kinase IG
CANT1 calcium activated nucleotidase 1
CBX4 chromobox homolog 4
CEACAM3 carcinoembryonic antigen-related cell adhesion molecule 3
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CENPI centromere protein I
CHKA choline kinase alpha
CLDN10 claudin 10
COL5A3 collagen, type V, alpha 3
COL8A2 collagen, type VIII, alpha 2
CTBP2 C-terminal binding protein 2
CUL5 cullin 5
DDAH2 dimethylarginine dimethylaminohydrolase 2
DLX2 distal-less homeobox 2
DOK5 docking protein 5
DUS2 dihydrouridine synthase 2
DUS4L dihydrouridine synthase 4-like (S. cerevisiae)
DUSP2 dual specificity phosphatase 2
ELMO2 engulfment and cell motility 2
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
ETV1 ets variant 1
FBXW4 F-box and WD repeat domain containing 4
FOLR1 folate receptor 1 (adult)
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GMEB1 glucocorticoid modulatory element binding protein 1
GPSM3 G-protein signaling modulator 3
HCRP1 hepatocellular carcinoma-related HCRP1
HDAC7 histone deacetylase 7
HFE hemochromatosis
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
IGSF6 immunoglobulin superfamily, member 6
IL1RAP interleukin 1 receptor accessory protein
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KDM5A lysine (K)-specific demethylase 5A
LINC00339 long intergenic non-protein coding RNA 339
LMF2 lipase maturation factor 2
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LUZP1 leucine zipper protein 1
MAN1B1 mannosidase, alpha, class 1B, member 1
METTL13 methyltransferase like 13
METTL5 methyltransferase like 5
MLC1 megalencephalic leukoencephalopathy with subcortical cysts 1
MPI mannose phosphate isomerase
MRPL12 mitochondrial ribosomal protein L12
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
MYL10 myosin, light chain 10, regulatory
NADK NAD kinase
NDRG2 NDRG family member 2
NELL2 NEL-like 2 (chicken)
ORC4 origin recognition complex, subunit 4
PAK1IP1 PAK1 interacting protein 1
PCIF1 PDX1 C-terminal inhibiting factor 1
PDE3B phosphodiesterase 3B, cGMP-inhibited
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
PKD1 polycystic kidney disease 1 (autosomal dominant)
PNPLA4 patatin-like phospholipase domain containing 4
POM121L2 POM121 transmembrane nucleoporin-like 2
PPP1R10 protein phosphatase 1, regulatory subunit 10
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit
RANBP1 RAN binding protein 1
RFK riboflavin kinase
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RPS4Y1 ribosomal protein S4, Y-linked 1
SEC23IP SEC23 interacting protein
SFSWAP splicing factor, suppressor of white-apricot family
SIDT2 SID1 transmembrane family, member 2
SLC16A7 solute carrier family 16 (monocarboxylate transporter), member 7
SLC35E3 solute carrier family 35, member E3
SLC39A1 solute carrier family 39 (zinc transporter), member 1
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7
SLC6A12 solute carrier family 6 (neurotransmitter transporter), member 12
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SLCO2A1 solute carrier organic anion transporter family, member 2A1
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal
SOAT1 sterol O-acyltransferase 1
SOD2 superoxide dismutase 2, mitochondrial
SORBS3 sorbin and SH3 domain containing 3
SOS1 son of sevenless homolog 1 (Drosophila)
SPN sialophorin
SSH3 slingshot protein phosphatase 3
STK25 serine/threonine kinase 25
TCL1A T-cell leukemia/lymphoma 1A
THTPA thiamine triphosphatase
USP20 ubiquitin specific peptidase 20
WAS Wiskott-Aldrich syndrome
WDR44 WD repeat domain 44
WWP2 WW domain containing E3 ubiquitin protein ligase 2
ZNF154 zinc finger protein 154
ZSWIM8 zinc finger, SWIM-type containing 8

decreased expression

Symbol Name
AATF apoptosis antagonizing transcription factor
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3
ALPK1 alpha-kinase 1
ANXA3 annexin A3
AP1G2 adaptor-related protein complex 1, gamma 2 subunit
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
ASCC1 activating signal cointegrator 1 complex subunit 1
BAHCC1 BAH domain and coiled-coil containing 1
C14ORF159 chromosome 14 open reading frame 159
C19ORF40 chromosome 19 open reading frame 40
C1ORF123 chromosome 1 open reading frame 123
C5ORF28 chromosome 5 open reading frame 28
CAPG capping protein (actin filament), gelsolin-like
CCDC88C coiled-coil domain containing 88C
CCNL2 cyclin L2
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CD300C CD300c molecule
CDCA8 cell division cycle associated 8
CEP85 centrosomal protein 85kDa
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin
CMTR1 cap methyltransferase 1
COQ4 coenzyme Q4
CRYBB2P1 crystallin, beta B2 pseudogene 1
CYB5R1 cytochrome b5 reductase 1
DCLRE1A DNA cross-link repair 1A
FBRS fibrosin
GSTA4 glutathione S-transferase alpha 4
GUSBP3 glucuronidase, beta pseudogene 3
HOXB5 homeobox B5
HRAS Harvey rat sarcoma viral oncogene homolog
IFITM3 interferon induced transmembrane protein 3
IGFLR1 IGF-like family receptor 1
KATNBL1 katanin p80 subunit B-like 1
KCTD9 potassium channel tetramerization domain containing 9
KIAA0894 KIAA0894 protein
KIFC1 kinesin family member C1
LAX1 lymphocyte transmembrane adaptor 1
LPAR6 lysophosphatidic acid receptor 6
LRP5L low density lipoprotein receptor-related protein 5-like
LRRC37A2 leucine rich repeat containing 37, member A2
LSP1 lymphocyte-specific protein 1
MAGOHB mago-nashi homolog B (Drosophila)
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5
MBOAT2 membrane bound O-acyltransferase domain containing 2
MCCC1 methylcrotonoyl-CoA carboxylase 1 (alpha)
MCRS1 microspherule protein 1
NDST2 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
NSD1 nuclear receptor binding SET domain protein 1
NUBP2 nucleotide binding protein 2
OGFRL1 opioid growth factor receptor-like 1
ORC2 origin recognition complex, subunit 2
PADI1 peptidyl arginine deiminase, type I
PEX26 peroxisomal biogenesis factor 26
PHLDA2 pleckstrin homology-like domain, family A, member 2
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PNRC1 proline-rich nuclear receptor coactivator 1
PODNL1 podocan-like 1
POGLUT1 protein O-glucosyltransferase 1
POM121 POM121 transmembrane nucleoporin
PRRC1 proline-rich coiled-coil 1
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein
RAB5B RAB5B, member RAS oncogene family
RAB8B RAB8B, member RAS oncogene family
RGP1 RGP1 retrograde golgi transport homolog (S. cerevisiae)
RIN1 Ras and Rab interactor 1
RNF220 ring finger protein 220
RNMTL1 RNA methyltransferase like 1
RPL23AP32 ribosomal protein L23a pseudogene 32
RRN3 RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae)
RUNX1-IT1 RUNX1 intronic transcript 1
SATB1 SATB homeobox 1
SCML1 sex comb on midleg-like 1 (Drosophila)
SETD1B SET domain containing 1B
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SLCO4A1 solute carrier organic anion transporter family, member 4A1
SLMO2 slowmo homolog 2 (Drosophila)
SLN sarcolipin
SLPI secretory leukocyte peptidase inhibitor
SPIN1 spindlin 1
SSSCA1 Sjogren syndrome/scleroderma autoantigen 1
STRA13 stimulated by retinoic acid 13
TFPT TCF3 (E2A) fusion partner (in childhood Leukemia)
TIMM10B translocase of inner mitochondrial membrane 10 homolog B (yeast)
TMED1 transmembrane emp24 protein transport domain containing 1
TMEM38B transmembrane protein 38B
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
UGGT1 UDP-glucose glycoprotein glucosyltransferase 1
UNG uracil-DNA glycosylase
WDR41 WD repeat domain 41
WDR82 WD repeat domain 82
WRN Werner syndrome, RecQ helicase-like
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
YIPF5 Yip1 domain family, member 5
ZNF184 zinc finger protein 184
ZNF426 zinc finger protein 426
ZNF767P zinc finger family member 767, pseudogene