antazoline-3173 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the antazoline-3173 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ALOX12 arachidonate 12-lipoxygenase
ALOX5AP arachidonate 5-lipoxygenase-activating protein
AQP7 aquaporin 7
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11
ARID5A AT rich interactive domain 5A (MRF1-like)
ARL3 ADP-ribosylation factor-like 3
ASIC1 acid sensing (proton gated) ion channel 1
ATPAF2 ATP synthase mitochondrial F1 complex assembly factor 2
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
BZRAP1 benzodiazepine receptor (peripheral) associated protein 1
C3ORF18 chromosome 3 open reading frame 18
CAMK4 calcium/calmodulin-dependent protein kinase IV
CASP1 caspase 1, apoptosis-related cysteine peptidase
CCDC33 coiled-coil domain containing 33
CCL5 chemokine (C-C motif) ligand 5
CLEC2B C-type lectin domain family 2, member B
CRMP1 collapsin response mediator protein 1
CXCL8 chemokine (C-X-C motif) ligand 8
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
DCBLD2 discoidin, CUB and LCCL domain containing 2
DDX25 DEAD (Asp-Glu-Ala-Asp) box helicase 25
DLC1 DLC1 Rho GTPase activating protein
ELANE elastase, neutrophil expressed
EPB41L4A erythrocyte membrane protein band 4.1 like 4A
EPX eosinophil peroxidase
ETV5 ets variant 5
FGF22 fibroblast growth factor 22
FH fumarate hydratase
FKBP10 FK506 binding protein 10, 65 kDa
FRY furry homolog (Drosophila)
FYB FYN binding protein
GIF gastric intrinsic factor (vitamin B synthesis)
GPC1 glypican 1
GPR15 G protein-coupled receptor 15
GPX1 glutathione peroxidase 1
GRK5 G protein-coupled receptor kinase 5
GRM8 glutamate receptor, metabotropic 8
GRPR gastrin-releasing peptide receptor
GSTA1 glutathione S-transferase alpha 1
HCK HCK proto-oncogene, Src family tyrosine kinase
HCLS1 hematopoietic cell-specific Lyn substrate 1
HFE hemochromatosis
HIST1H2AK histone cluster 1, H2ak
HOMER3 homer scaffolding protein 3
HRH4 histamine receptor H4
IFI44 interferon-induced protein 44
IGHMBP2 immunoglobulin mu binding protein 2
ING2 inhibitor of growth family, member 2
INO80D INO80 complex subunit D
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
LAPTM5 lysosomal protein transmembrane 5
LAT2 linker for activation of T cells family, member 2
LDHB lactate dehydrogenase B
LMF2 lipase maturation factor 2
LST1 leukocyte specific transcript 1
LYZ lysozyme
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
MMP3 matrix metallopeptidase 3
MPO myeloperoxidase
MS4A3 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
MSN moesin
MSR1 macrophage scavenger receptor 1
NMT2 N-myristoyltransferase 2
NOL10 nucleolar protein 10
NPPA natriuretic peptide A
NRN1 neuritin 1
NT5M 5',3'-nucleotidase, mitochondrial
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
P2RX6 purinergic receptor P2X, ligand gated ion channel, 6
PAX8 paired box 8
PCDHB6 protocadherin beta 6
PCYT1B phosphate cytidylyltransferase 1, choline, beta
PDE11A phosphodiesterase 11A
PECAM1 platelet/endothelial cell adhesion molecule 1
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)
PRICKLE3 prickle homolog 3 (Drosophila)
PRTN3 proteinase 3
PSD3 pleckstrin and Sec7 domain containing 3
RAB6A RAB6A, member RAS oncogene family
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
RERE arginine-glutamic acid dipeptide (RE) repeats
RTEL1 regulator of telomere elongation helicase 1
S100A8 S100 calcium binding protein A8
SCN2A sodium channel, voltage gated, type II alpha subunit
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SPAG8 sperm associated antigen 8
SRGN serglycin
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
TAT tyrosine aminotransferase
TFF2 trefoil factor 2
TMEM259 transmembrane protein 259
TPMT thiopurine S-methyltransferase
TRIB2 tribbles pseudokinase 2
TYMP thymidine phosphorylase
TYROBP TYRO protein tyrosine kinase binding protein
WIPF1 WAS/WASL interacting protein family, member 1
ZNF419 zinc finger protein 419

decreased expression

Symbol Name
ACTG2 actin, gamma 2, smooth muscle, enteric
ADCY7 adenylate cyclase 7
ADGRG2 adhesion G protein-coupled receptor G2
ADM adrenomedullin
AFAP1 actin filament associated protein 1
ANP32A-IT1 ANP32A intronic transcript 1
ARNTL2 aryl hydrocarbon receptor nuclear translocator-like 2
BAHCC1 BAH domain and coiled-coil containing 1
C1QTNF3 C1q and tumor necrosis factor related protein 3
C2ORF27A chromosome 2 open reading frame 27A
C8ORF60 chromosome 8 open reading frame 60
CBX8 chromobox homolog 8
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CCNK cyclin K
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
CRY2 cryptochrome circadian clock 2
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DOC2A double C2-like domains, alpha
DPY19L1P1 DPY19L1 pseudogene 1
ENO2 enolase 2 (gamma, neuronal)
ENO3 enolase 3 (beta, muscle)
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
EXOC6B exocyst complex component 6B
FBXO22 F-box protein 22
FBXW4P1 F-box and WD repeat domain containing 4 pseudogene 1
FGF4 fibroblast growth factor 4
FKBP5 FK506 binding protein 5
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2
HIST1H2AL histone cluster 1, H2al
HIST1H2BI histone cluster 1, H2bi
HMOX1 heme oxygenase 1
HOXC5 homeobox C5
IDI2-AS1 IDI2 antisense RNA 1
INCENP inner centromere protein antigens 135/155kDa
IQSEC2 IQ motif and Sec7 domain 2
ITGA10 integrin, alpha 10
KIFC1 kinesin family member C1
LLPH LLP homolog, long-term synaptic facilitation (Aplysia)
LOC257152 uncharacterized LOC257152
LPAR4 lysophosphatidic acid receptor 4
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1
MBNL3 muscleblind-like splicing regulator 3
NDOR1 NADPH dependent diflavin oxidoreductase 1
NEUROD4 neuronal differentiation 4
NLRX1 NLR family member X1
NNAT neuronatin
NPIPB3 nuclear pore complex interacting protein family, member B3
NRSN2 neurensin 2
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
PACS1 phosphofurin acidic cluster sorting protein 1
PGGT1B protein geranylgeranyltransferase type I, beta subunit
PHC1 polyhomeotic homolog 1 (Drosophila)
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLD2 phospholipase D2
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta
PROL1 proline rich, lacrimal 1
RAB11FIP5 RAB11 family interacting protein 5 (class I)
RASAL1 RAS protein activator like 1 (GAP1 like)
RASL11B RAS-like, family 11, member B
RNF121 ring finger protein 121
RNF122 ring finger protein 122
RUNDC3B RUN domain containing 3B
SCGB2A2 secretoglobin, family 2A, member 2
SCNN1B sodium channel, non voltage gated 1 beta subunit
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC22A14 solute carrier family 22, member 14
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLMO1 slowmo homolog 1 (Drosophila)
STARD5 StAR-related lipid transfer (START) domain containing 5
STX1A syntaxin 1A (brain)
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TAOK1 TAO kinase 1
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TCP10 t-complex 10
THBS3 thrombospondin 3
THNSL1 threonine synthase-like 1 (S. cerevisiae)
TMEM212 transmembrane protein 212
TNS2 tensin 2
TUBA3C tubulin, alpha 3c
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
VASH2 vasohibin 2
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
WDR62 WD repeat domain 62
WDR76 WD repeat domain 76
WNT10B wingless-type MMTV integration site family, member 10B
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZDHHC11 zinc finger, DHHC-type containing 11
ZNF227 zinc finger protein 227
ZNF34 zinc finger protein 34