antigen processing and presentation of endogenous peptide antigen via MHC class I Gene Set

Dataset GO Biological Process Annotations 2025
Category structural or functional annotations
Type biological process
Description The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class I protein complex. The peptide antigen is typically, but not always, processed from a whole protein. Class I here refers to classical class I molecules. (Gene Ontology, GO_0019885)
External Link http://amigo.geneontology.org/amigo/term/GO:0019885
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Genes

7 genes participating in the antigen processing and presentation of endogenous peptide antigen via MHC class I biological process from the curated GO Biological Process Annotations 2025 dataset.

Symbol Name
B2M beta-2-microglobulin
ERAP1 endoplasmic reticulum aminopeptidase 1
ERAP2 endoplasmic reticulum aminopeptidase 2
HLA-A major histocompatibility complex, class I, A
IDE insulin-degrading enzyme
SEC14L2 SEC14-like 2 (S. cerevisiae)
SEC14L3 SEC14-like 3 (S. cerevisiae)