antigen processing and presentation of endogenous peptide antigen Gene Set

Dataset GO Biological Process Annotations 2025
Category structural or functional annotations
Type biological process
Description The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC protein complex. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell. (Gene Ontology, GO_0002483)
External Link http://amigo.geneontology.org/amigo/term/GO:0002483
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Genes

22 genes participating in the antigen processing and presentation of endogenous peptide antigen biological process from the curated GO Biological Process Annotations 2025 dataset.

Symbol Name
AZGP1 alpha-2-glycoprotein 1, zinc-binding
B2M beta-2-microglobulin
ERAP1 endoplasmic reticulum aminopeptidase 1
ERAP2 endoplasmic reticulum aminopeptidase 2
HFE hemochromatosis
HLA-A major histocompatibility complex, class I, A
HLA-B major histocompatibility complex, class I, B
HLA-C major histocompatibility complex, class I, C
HLA-DRA major histocompatibility complex, class II, DR alpha
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HLA-E major histocompatibility complex, class I, E
HLA-F major histocompatibility complex, class I, F
HLA-G major histocompatibility complex, class I, G
IDE insulin-degrading enzyme
RAET1E retinoic acid early transcript 1E
RAET1G retinoic acid early transcript 1G
RAET1L retinoic acid early transcript 1L
SEC14L2 SEC14-like 2 (S. cerevisiae)
SEC14L3 SEC14-like 3 (S. cerevisiae)
ULBP1 UL16 binding protein 1
ULBP2 UL16 binding protein 2
ULBP3 UL16 binding protein 3