antioxidant activity Gene Set

Dataset GO Molecular Function Annotations 2015
Category structural or functional annotations
Type molecular function
Description Inhibition of the reactions brought about by dioxygen (O2) or peroxides. Usually the antioxidant is effective because it can itself be more easily oxidized than the substance protected. The term is often applied to components that can trap free radicals, thereby breaking the chain reaction that normally leads to extensive biological damage. (Gene Ontology, GO_0016209)
External Link http://amigo.geneontology.org/amigo/term/GO:0016209
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Genes

66 genes performing the antioxidant activity molecular function from the curated GO Molecular Function Annotations 2015 dataset.

Symbol Name
ALB albumin
ALOX5AP arachidonate 5-lipoxygenase-activating protein
APOE apolipoprotein E
APOM apolipoprotein M
CAT catalase
CCS copper chaperone for superoxide dismutase
CLIC2 chloride intracellular channel 2
CYGB cytoglobin
DUOX1 dual oxidase 1
DUOX2 dual oxidase 2
EPX eosinophil peroxidase
FABP1 fatty acid binding protein 1, liver
FAM213A family with sequence similarity 213, member A
GPX1 glutathione peroxidase 1
GPX2 glutathione peroxidase 2
GPX3 glutathione peroxidase 3
GPX4 glutathione peroxidase 4
GPX5 glutathione peroxidase 5
GPX6 glutathione peroxidase 6
GPX7 glutathione peroxidase 7
GPX8 glutathione peroxidase 8 (putative)
GSR glutathione reductase
GSTK1 glutathione S-transferase kappa 1
GSTO1 glutathione S-transferase omega 1
GSTO2 glutathione S-transferase omega 2
GSTT1 glutathione S-transferase theta 1
GSTZ1 glutathione S-transferase zeta 1
HBB hemoglobin, beta
HP haptoglobin
IPCEF1 interaction protein for cytohesin exchange factors 1
IYD iodotyrosine deiodinase
LPO lactoperoxidase
LTC4S leukotriene C4 synthase
MGST1 microsomal glutathione S-transferase 1
MGST2 microsomal glutathione S-transferase 2
MGST3 microsomal glutathione S-transferase 3
MPO myeloperoxidase
MT3 metallothionein 3
NQO1 NAD(P)H dehydrogenase, quinone 1
NXN nucleoredoxin
PARK7 parkinson protein 7
PRDX1 peroxiredoxin 1
PRDX2 peroxiredoxin 2
PRDX3 peroxiredoxin 3
PRDX4 peroxiredoxin 4
PRDX5 peroxiredoxin 5
PRDX6 peroxiredoxin 6
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PXDN peroxidasin
PXDNL peroxidasin-like
S100A9 S100 calcium binding protein A9
SEPW1 selenoprotein W, 1
SOD1 superoxide dismutase 1, soluble
SOD2 superoxide dismutase 2, mitochondrial
SOD3 superoxide dismutase 3, extracellular
SRXN1 sulfiredoxin 1
TP53INP1 tumor protein p53 inducible nuclear protein 1
TPO thyroid peroxidase
TXNDC17 thioredoxin domain containing 17
TXNDC2 thioredoxin domain containing 2 (spermatozoa)
TXNRD1 thioredoxin reductase 1
TXNRD2 thioredoxin reductase 2
TXNRD3 thioredoxin reductase 3
UBIAD1 UbiA prenyltransferase domain containing 1
VIMP VCP-interacting membrane selenoprotein