antioxidant Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description A substance that opposes oxidation or inhibits reactions brought about by dioxygen or peroxides. In European countries, E-numbers for permitted antioxidant food additives are from E 300 to E 324. (Chemical Entities of Biological Interest Ontology, CHEBI_22586)
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Genes

196 genes co-occuring with the biological term antioxidant in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ACHE acetylcholinesterase (Yt blood group)
ACTB actin, beta
ACTN3 actinin, alpha 3 (gene/pseudogene)
ADIPOQ adiponectin, C1Q and collagen domain containing
AFP alpha-fetoprotein
AGER advanced glycosylation end product-specific receptor
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AKR1C2 aldo-keto reductase family 1, member C2
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALB albumin
ALOX5 arachidonate 5-lipoxygenase
APLN apelin
APOA2 apolipoprotein A-II
APOA4 apolipoprotein A-IV
APOA5 apolipoprotein A-V
APOC3 apolipoprotein C-III
APOE apolipoprotein E
APOM apolipoprotein M
APP amyloid beta (A4) precursor protein
ATM ATM serine/threonine kinase
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide
ATXN3 ataxin 3
BAX BCL2-associated X protein
BCL2 B-cell CLL/lymphoma 2
BLVRA biliverdin reductase A
BMI1 BMI1 proto-oncogene, polycomb ring finger
BRD2 bromodomain containing 2
BRD4 bromodomain containing 4
BTG2 BTG family, member 2
CA3 carbonic anhydrase III
CA4 carbonic anhydrase IV
CALR calreticulin
CARTPT CART prepropeptide
CAT catalase
CAV1 caveolin 1, caveolae protein, 22kDa
CBR3 carbonyl reductase 3
CBS cystathionine-beta-synthase
CCL2 chemokine (C-C motif) ligand 2
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma
CERKL ceramide kinase-like
CES1 carboxylesterase 1
CFLAR CASP8 and FADD-like apoptosis regulator
CHRNA7 cholinergic receptor, nicotinic, alpha 7 (neuronal)
CLU clusterin
CP ceruloplasmin (ferroxidase)
CREM cAMP responsive element modulator
CRP C-reactive protein, pentraxin-related
CUL3 cullin 3
CYB5R3 cytochrome b5 reductase 3
CYBB cytochrome b-245, beta polypeptide
DMPK dystrophia myotonica-protein kinase
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
EDN1 endothelin 1
EP300 E1A binding protein p300
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
EPO erythropoietin
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
FANCD2 Fanconi anemia, complementation group D2
FGF2 fibroblast growth factor 2 (basic)
FOXO1 forkhead box O1
FOXO3 forkhead box O3
FOXO4 forkhead box O4
FTH1 ferritin, heavy polypeptide 1
FTL ferritin, light polypeptide
G6PD glucose-6-phosphate dehydrogenase
GCLC glutamate-cysteine ligase, catalytic subunit
GFER growth factor, augmenter of liver regeneration
GLS2 glutaminase 2 (liver, mitochondrial)
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
GPX1 glutathione peroxidase 1
GPX3 glutathione peroxidase 3
GPX4 glutathione peroxidase 4
GSK3B glycogen synthase kinase 3 beta
GSN gelsolin
GSR glutathione reductase
GSTM1 glutathione S-transferase mu 1
GSTP1 glutathione S-transferase pi 1
H6PD hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
HDAC2 histone deacetylase 2
HFE hemochromatosis
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HIPK2 homeodomain interacting protein kinase 2
HK2 hexokinase 2
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HMOX1 heme oxygenase 1
HMOX2 heme oxygenase 2
HP haptoglobin
HSF1 heat shock transcription factor 1
HSPA1A heat shock 70kDa protein 1A
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial
IL10 interleukin 10
IL1B interleukin 1, beta
IL6 interleukin 6
JDP2 Jun dimerization protein 2
JUN jun proto-oncogene
JUND jun D proto-oncogene
KDR kinase insert domain receptor
KEAP1 kelch-like ECH-associated protein 1
KLF2 Kruppel-like factor 2
LANCL1 LanC lantibiotic synthetase component C-like 1 (bacterial)
LCAT lecithin-cholesterol acyltransferase
LCN1 lipocalin 1
LEPR leptin receptor
LETM1 leucine zipper-EF-hand containing transmembrane protein 1
LIAS lipoic acid synthetase
LTF lactotransferrin
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G
MAFK v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K
MAPK14 mitogen-activated protein kinase 14
MAPK8 mitogen-activated protein kinase 8
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MIR17 microRNA 17
MPO myeloperoxidase
MSRA methionine sulfoxide reductase A
NFE2L2 nuclear factor, erythroid 2-like 2
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NGB neuroglobin
NNT nicotinamide nucleotide transhydrogenase
NOS3 nitric oxide synthase 3 (endothelial cell)
NOX4 NADPH oxidase 4
NPC1 Niemann-Pick disease, type C1
NQO1 NAD(P)H dehydrogenase, quinone 1
OGG1 8-oxoguanine DNA glycosylase
OLA1 Obg-like ATPase 1
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1
PARK2 parkin RBR E3 ubiquitin protein ligase
PARK7 parkinson protein 7
PARP1 poly (ADP-ribose) polymerase 1
PDIA3 protein disulfide isomerase family A, member 3
PEPD peptidase D
PHB prohibitin
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PLTP phospholipid transfer protein
PON1 paraoxonase 1
PON3 paraoxonase 3
PPARA peroxisome proliferator-activated receptor alpha
PPARG peroxisome proliferator-activated receptor gamma
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PRDX1 peroxiredoxin 1
PRDX2 peroxiredoxin 2
PRDX4 peroxiredoxin 4
PRDX5 peroxiredoxin 5
PRDX6 peroxiredoxin 6
PREP prolyl endopeptidase
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKCD protein kinase C, delta
PRRX2 paired related homeobox 2
PTEN phosphatase and tensin homolog
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTPN12 protein tyrosine phosphatase, non-receptor type 12
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RETN resistin
RLN2 relaxin 2
RORA RAR-related orphan receptor A
S100A6 S100 calcium binding protein A6
SCARB1 scavenger receptor class B, member 1
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein
SELK selenoprotein K
SERPINA4 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SIRT1 sirtuin 1
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC22A12 solute carrier family 22 (organic anion/urate transporter), member 12
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2
SMPD3 sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SOD1 superoxide dismutase 1, soluble
SOD2 superoxide dismutase 2, mitochondrial
SOD3 superoxide dismutase 3, extracellular
SQSTM1 sequestosome 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STC1 stanniocalcin 1
TERT telomerase reverse transcriptase
TFAM transcription factor A, mitochondrial
TGS1 trimethylguanosine synthase 1
TH tyrosine hydroxylase
TNF tumor necrosis factor
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TOP2B topoisomerase (DNA) II beta 180kDa
TP53 tumor protein p53
TXN thioredoxin
TXN2 thioredoxin 2
TXNRD1 thioredoxin reductase 1
TXNRD2 thioredoxin reductase 2
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1
VEGFA vascular endothelial growth factor A
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1