antiphospholipid syndrome Gene Set

Dataset GAD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A hypersensitivity reaction type II disease that is characterized by recurrent venous or arterial thrombosis and/or fetal losses associated with characteristic elevated levels of antibodies directed against membrane anionic phospholipids (anticardiolipin). (Human Disease Ontology, DOID_2988)
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Genes

13 genes associated with the disease antiphospholipid syndrome in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

Symbol Name
APOH apolipoprotein H (beta-2-glycoprotein I)
F2 coagulation factor II (thrombin)
F5 coagulation factor V (proaccelerin, labile factor)
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
HLA-DMA major histocompatibility complex, class II, DM alpha
HLA-DMB major histocompatibility complex, class II, DM beta
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
STAT4 signal transducer and activator of transcription 4
TNF tumor necrosis factor