antiproliferative Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

245 genes co-occuring with the biological term antiproliferative in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ACE2 angiotensin I converting enzyme 2
ACVR1C activin A receptor, type IC
ADIPOQ adiponectin, C1Q and collagen domain containing
ADM adrenomedullin
AKR1C3 aldo-keto reductase family 1, member C3
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALDH1L1 aldehyde dehydrogenase 1 family, member L1
ALOX12 arachidonate 12-lipoxygenase
ALOX15 arachidonate 15-lipoxygenase
ALOX5 arachidonate 5-lipoxygenase
ANGPT1 angiopoietin 1
APOE apolipoprotein E
AR androgen receptor
ARF1 ADP-ribosylation factor 1
ARRB2 arrestin, beta 2
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1
ATM ATM serine/threonine kinase
AURKB aurora kinase B
BCL2 B-cell CLL/lymphoma 2
BCL2L1 BCL2-like 1
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BCL6 B-cell CLL/lymphoma 6
BGN biglycan
BHLHE40 basic helix-loop-helix family, member e40
BIRC5 baculoviral IAP repeat containing 5
BMP2 bone morphogenetic protein 2
BMP4 bone morphogenetic protein 4
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase)
BTG1 B-cell translocation gene 1, anti-proliferative
BTG2 BTG family, member 2
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP7 caspase 7, apoptosis-related cysteine peptidase
CAV1 caveolin 1, caveolae protein, 22kDa
CAV2 caveolin 2
CCKBR cholecystokinin B receptor
CCND1 cyclin D1
CCNG2 cyclin G2
CD33 CD33 molecule
CDC25C cell division cycle 25C
CDK4 cyclin-dependent kinase 4
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CHFR checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase
CHKA choline kinase alpha
CHRNA7 cholinergic receptor, nicotinic, alpha 7 (neuronal)
CKAP4 cytoskeleton-associated protein 4
CLDN4 claudin 4
CLU clusterin
CNOT7 CCR4-NOT transcription complex, subunit 7
CNOT8 CCR4-NOT transcription complex, subunit 8
CNR2 cannabinoid receptor 2 (macrophage)
CR2 complement component (3d/Epstein Barr virus) receptor 2
CRABP2 cellular retinoic acid binding protein 2
CTGF connective tissue growth factor
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CXCR4 chemokine (C-X-C motif) receptor 4
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
CYTH1 cytohesin 1
DCN decorin
DDIT4 DNA-damage-inducible transcript 4
DLC1 DLC1 Rho GTPase activating protein
DLX4 distal-less homeobox 4
DUSP1 dual specificity phosphatase 1
E2F1 E2F transcription factor 1
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
EGF epidermal growth factor
EGFR epidermal growth factor receptor
EGLN3 egl-9 family hypoxia-inducible factor 3
EIF5A eukaryotic translation initiation factor 5A
EPHB2 EPH receptor B2
ERBB2 erb-b2 receptor tyrosine kinase 2
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
ETV3 ets variant 3
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
F2R coagulation factor II (thrombin) receptor
FANCF Fanconi anemia, complementation group F
FGFR1 fibroblast growth factor receptor 1
FHIT fragile histidine triad
FOS FBJ murine osteosarcoma viral oncogene homolog
FOXL2 forkhead box L2
FOXO1 forkhead box O1
FZD8 frizzled class receptor 8
GALNT2 polypeptide N-acetylgalactosaminyltransferase 2
GBP1 guanylate binding protein 1, interferon-inducible
GH1 growth hormone 1
GHRH growth hormone releasing hormone
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
GNRHR gonadotropin-releasing hormone receptor
GSTP1 glutathione S-transferase pi 1
HDAC1 histone deacetylase 1
HEPACAM hepatic and glial cell adhesion molecule
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HIPK2 homeodomain interacting protein kinase 2
HLA-C major histocompatibility complex, class I, C
HMOX1 heme oxygenase 1
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IFN1@ interferon, type 1, cluster
IFNA1 interferon, alpha 1
IFNA2 interferon, alpha 2
IFNAR1 interferon (alpha, beta and omega) receptor 1
IFNAR2 interferon (alpha, beta and omega) receptor 2
IFNB1 interferon, beta 1, fibroblast
IFNG interferon, gamma
IFNL1 interferon, lambda 1
IFNL2 interferon, lambda 2
IFNLR1 interferon, lambda receptor 1
IGF1R insulin-like growth factor 1 receptor
IGFBP3 insulin-like growth factor binding protein 3
IGFBP6 insulin-like growth factor binding protein 6
IL27 interleukin 27
IL6 interleukin 6
IRF1 interferon regulatory factor 1
IRF9 interferon regulatory factor 9
JUN jun proto-oncogene
JUND jun D proto-oncogene
KCNH1 potassium channel, voltage gated eag related subfamily H, member 1
KDR kinase insert domain receptor
KISS1 KiSS-1 metastasis-suppressor
KRAS Kirsten rat sarcoma viral oncogene homolog
LEP leptin
LTF lactotransferrin
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPK8 mitogen-activated protein kinase 8
MCL1 myeloid cell leukemia 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MDM4 MDM4, p53 regulator
MECOM MDS1 and EVI1 complex locus
MEN1 multiple endocrine neoplasia I
MET MET proto-oncogene, receptor tyrosine kinase
MIR1-1 microRNA 1-1
MIR106B microRNA 106b
MIR124-1 microRNA 124-1
MIR133B microRNA 133b
MIR17 microRNA 17
MIR208A microRNA 208a
MIR20A microRNA 20a
MIR24-1 microRNA 24-1
MIR424 microRNA 424
MIR503 microRNA 503
MMP2 matrix metallopeptidase 2
MMP9 matrix metallopeptidase 9
MPL MPL proto-oncogene, thrombopoietin receptor
MST1 macrophage stimulating 1
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MYC v-myc avian myelocytomatosis viral oncogene homolog
NAP1L1 nucleosome assembly protein 1-like 1
NCOR2 nuclear receptor corepressor 2
NDRG1 N-myc downstream regulated 1
NES nestin
NF2 neurofibromin 2 (merlin)
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NKX3-1 NK3 homeobox 1
NOS1 nitric oxide synthase 1 (neuronal)
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NRG1 neuregulin 1
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OGDHL oxoglutarate dehydrogenase-like
ORAI1 ORAI calcium release-activated calcium modulator 1
PARP1 poly (ADP-ribose) polymerase 1
PARP9 poly (ADP-ribose) polymerase family, member 9
PCDH17 protocadherin 17
PCSK6 proprotein convertase subtilisin/kexin type 6
PDGFB platelet-derived growth factor beta polypeptide
PGR progesterone receptor
PIAS3 protein inhibitor of activated STAT, 3
PKD1 polycystic kidney disease 1 (autosomal dominant)
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
PLD1 phospholipase D1, phosphatidylcholine-specific
PPARA peroxisome proliferator-activated receptor alpha
PPARG peroxisome proliferator-activated receptor gamma
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKCB protein kinase C, beta
PRKG2 protein kinase, cGMP-dependent, type II
PTEN phosphatase and tensin homolog
PTH1R parathyroid hormone 1 receptor
PTPN6 protein tyrosine phosphatase, non-receptor type 6
RAPGEF3 Rap guanine nucleotide exchange factor (GEF) 3
RB1 retinoblastoma 1
RBM5 RNA binding motif protein 5
RFPL1 ret finger protein-like 1
RUNX1 runt-related transcription factor 1
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
SAT1 spermidine/spermine N1-acetyltransferase 1
SEC14L2 SEC14-like 2 (S. cerevisiae)
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SKIL SKI-like proto-oncogene
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
SMAD1 SMAD family member 1
SMAD2 SMAD family member 2
SMAD3 SMAD family member 3
SMOX spermine oxidase
SOCS1 suppressor of cytokine signaling 1
SOD2 superoxide dismutase 2, mitochondrial
SP1 Sp1 transcription factor
SPHK1 sphingosine kinase 1
SPRY2 sprouty homolog 2 (Drosophila)
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SSTR2 somatostatin receptor 2
SSTR5 somatostatin receptor 5
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
TBX3 T-box 3
TERT telomerase reverse transcriptase
TFCP2 transcription factor CP2
TGFB1 transforming growth factor, beta 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
THRB thyroid hormone receptor, beta
TIMP2 TIMP metallopeptidase inhibitor 2
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TOB1 transducer of ERBB2, 1
TOB2 transducer of ERBB2, 2
TP53 tumor protein p53
TRIM21 tripartite motif containing 21
TRIM22 tripartite motif containing 22
TRPM7 transient receptor potential cation channel, subfamily M, member 7
TSPYL2 TSPY-like 2
TXN thioredoxin
UBQLN1 ubiquilin 1
UMPS uridine monophosphate synthetase
USP18 ubiquitin specific peptidase 18
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VIP vasoactive intestinal peptide
WNT3A wingless-type MMTV integration site family, member 3A
ZFP36 ZFP36 ring finger protein