ap-3 adaptor complex Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A heterotetrameric AP-type membrane coat adaptor complex that consists of beta3, delta, mu3 and sigma3 subunits and is found associated with endosomal membranes. AP-3 does not appear to associate with clathrin in all organisms. In at least humans, the AP-3 complex can be heterogeneric due to the existence of multiple subunit isoforms encoded by different genes (beta3A and beta3B, mu3A and mu3B, and sigma3A and sigma3B). (Gene Ontology, GO_0030123)
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41 proteins co-occuring with the ap-3 adaptor complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
AP3S1 adaptor-related protein complex 3, sigma 1 subunit 1.5776
HPS1 Hermansky-Pudlak syndrome 1 1.1603
CDC42EP4 CDC42 effector protein (Rho GTPase binding) 4 1.09594
AP3D1 adaptor-related protein complex 3, delta 1 subunit 1.08831
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 1.01139
BLOC1S6 biogenesis of lysosomal organelles complex-1, subunit 6, pallidin 0.924666
RAB31 RAB31, member RAS oncogene family 0.85388
AP3B1 adaptor-related protein complex 3, beta 1 subunit 0.733319
UNC13D unc-13 homolog D (C. elegans) 0.709251
MLST8 MTOR associated protein, LST8 homolog (S. cerevisiae) 0.706156
ARF1 ADP-ribosylation factor 1 0.671593
RAB32 RAB32, member RAS oncogene family 0.670292
USO1 USO1 vesicle transport factor 0.659482
AP1M2 adaptor-related protein complex 1, mu 2 subunit 0.641001
AP2M1 adaptor-related protein complex 2, mu 1 subunit 0.638434
ARF5 ADP-ribosylation factor 5 0.62393
LYST lysosomal trafficking regulator 0.620954
CD63 CD63 molecule 0.601066
CD1B CD1b molecule 0.569248
SNAPIN SNAP-associated protein 0.556387
CLTC clathrin, heavy chain (Hc) 0.517756
TFRC transferrin receptor 0.4676
LAMP2 lysosomal-associated membrane protein 2 0.386208
STX2 syntaxin 2 0.378122
ALPPL2 alkaline phosphatase, placental-like 2 0.372366
ALPL alkaline phosphatase, liver/bone/kidney 0.371982
ALPP alkaline phosphatase, placental 0.371599
SLC36A4 solute carrier family 36 (proton/amino acid symporter), member 4 0.366623
GSTM1 glutathione S-transferase mu 1 0.354802
PGRMC1 progesterone receptor membrane component 1 0.346071
STX4 syntaxin 4 0.320077
LAMP1 lysosomal-associated membrane protein 1 0.319328
MGAT4C MGAT4 family, member C 0.285876
RAB27A RAB27A, member RAS oncogene family 0.275936
SNAP23 synaptosomal-associated protein, 23kDa 0.24424
RAP2B RAP2B, member of RAS oncogene family 0.217511
SAR1A secretion associated, Ras related GTPase 1A 0.21124
ARF3 ADP-ribosylation factor 3 0.210894
RAB1B RAB1B, member RAS oncogene family 0.208481
ARF6 ADP-ribosylation factor 6 0.19307
SEPT5 septin 5 0.180634