ap-type membrane coat adaptor complex Gene Set

Dataset GO Cellular Component Annotations
Category structural or functional annotations
Type cellular component
Description Any of several heterotetrameric complexes that link clathrin (or another coat-forming molecule, as hypothesized for AP-3 and AP-4) to a membrane surface; they are found on coated pits and coated vesicles, and mediate sorting of cargo proteins into vesicles. Each AP complex contains two large (a beta and one of either an alpha, gamma, delta, or epsilon) subunits (110-130 kDa), a medium (mu) subunit (approximately 50 kDa), and a small (sigma) subunit (15-20 kDa). (Gene Ontology, GO_0030119)
External Link http://amigo.geneontology.org/amigo/term/GO:0030119
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Genes

38 proteins localized to the ap-type membrane coat adaptor complex cellular component from the curated GO Cellular Component Annotations dataset.

Symbol Name
AFTPH aftiphilin
AP1B1 adaptor-related protein complex 1, beta 1 subunit
AP1G1 adaptor-related protein complex 1, gamma 1 subunit
AP1G2 adaptor-related protein complex 1, gamma 2 subunit
AP1M1 adaptor-related protein complex 1, mu 1 subunit
AP1M2 adaptor-related protein complex 1, mu 2 subunit
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
AP1S2 adaptor-related protein complex 1, sigma 2 subunit
AP2A1 adaptor-related protein complex 2, alpha 1 subunit
AP2A2 adaptor-related protein complex 2, alpha 2 subunit
AP2B1 adaptor-related protein complex 2, beta 1 subunit
AP2M1 adaptor-related protein complex 2, mu 1 subunit
AP2S1 adaptor-related protein complex 2, sigma 1 subunit
AP3B1 adaptor-related protein complex 3, beta 1 subunit
AP3B2 adaptor-related protein complex 3, beta 2 subunit
AP3M1 adaptor-related protein complex 3, mu 1 subunit
AP3M2 adaptor-related protein complex 3, mu 2 subunit
AP3S1 adaptor-related protein complex 3, sigma 1 subunit
AP3S2 adaptor-related protein complex 3, sigma 2 subunit
AP4B1 adaptor-related protein complex 4, beta 1 subunit
AP4M1 adaptor-related protein complex 4, mu 1 subunit
AP5B1 adaptor-related protein complex 5, beta 1 subunit
AP5M1 adaptor-related protein complex 5, mu 1 subunit
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
AP5Z1 adaptor-related protein complex 5, zeta 1 subunit
ARCN1 archain 1
EGFR epidermal growth factor receptor
EPS15 epidermal growth factor receptor pathway substrate 15
GGA1 golgi-associated, gamma adaptin ear containing, ARF binding protein 1
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2
GGA3 golgi-associated, gamma adaptin ear containing, ARF binding protein 3
LDLRAP1 low density lipoprotein receptor adaptor protein 1
LRRN3 leucine rich repeat neuronal 3
PICALM phosphatidylinositol binding clathrin assembly protein
SGIP1 SH3-domain GRB2-like (endophilin) interacting protein 1
STON2 stonin 2
SYNRG synergin, gamma
TBC1D5 TBC1 domain family, member 5
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