| Dataset | GeneRIF Biological Term Annotations |
| Category | structural or functional annotations |
| Type | biological term |
| Description | APH1B gamma secretase subunit|This gene encodes a multi-pass transmembrane protein that is a functional component of the gamma-secretase complex, which also contains presenilin and nicastrin. This protein represents a stabilizing cofactor for the presenilin holoprotein in the complex. The gamma-secretase complex catalyzes the cleavage of integral proteins such as notch receptors and beta-amyloid precursor protein. [provided by RefSeq, Sep 2011] (NCBI Entrez Gene Database, 83464) |
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5 genes co-occuring with the biological term aph1b in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.
