apical junction complex Gene Set

Dataset GO Cellular Component Annotations 2015
Category structural or functional annotations
Type cellular component
Description A functional unit located near the cell apex at the points of contact between epithelial cells, which in vertebrates is composed of the tight junction, the zonula adherens, and desmosomes and in some invertebrates, such as Drosophila, is composed of the subapical complex (SAC), the zonula adherens and the septate junction. Functions in the regulation of cell polarity, tissue integrity and intercellular adhesion and permeability. (Gene Ontology, GO_0043296)
External Link http://amigo.geneontology.org/amigo/term/GO:0043296
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Genes

10 proteins localized to the apical junction complex cellular component from the curated GO Cellular Component Annotations 2015 dataset.

Symbol Name
CCDC85C coiled-coil domain containing 85C
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CLDN19 claudin 19
FBF1 Fas (TNFRSF6) binding factor 1
FRMD6 FERM domain containing 6
PKN2 protein kinase N2
PVRL3 poliovirus receptor-related 3
RHOA ras homolog family member A
SHROOM3 shroom family member 3
TJP1 tight junction protein 1