| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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199 genes differentially expressed following the apigenin-3257 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACTA2 | actin, alpha 2, smooth muscle, aorta |
| AEN | apoptosis enhancing nuclease |
| AIM2 | absent in melanoma 2 |
| ALDH3B1 | aldehyde dehydrogenase 3 family, member B1 |
| ALDH8A1 | aldehyde dehydrogenase 8 family, member A1 |
| APOLD1 | apolipoprotein L domain containing 1 |
| BAIAP3 | BAI1-associated protein 3 |
| BBS1 | Bardet-Biedl syndrome 1 |
| BMP15 | bone morphogenetic protein 15 |
| C11ORF1 | chromosome 11 open reading frame 1 |
| C11ORF63 | chromosome 11 open reading frame 63 |
| C14ORF79 | chromosome 14 open reading frame 79 |
| CATSPERB | catsper channel auxiliary subunit beta |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 |
| CCDC71 | coiled-coil domain containing 71 |
| CCDC88C | coiled-coil domain containing 88C |
| CCNT2 | cyclin T2 |
| CD59 | CD59 molecule, complement regulatory protein |
| CD82 | CD82 molecule |
| CDKL3 | cyclin-dependent kinase-like 3 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CEL | carboxyl ester lipase |
| CRY2 | cryptochrome circadian clock 2 |
| CSTF3 | cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa |
| CYP27A1 | cytochrome P450, family 27, subfamily A, polypeptide 1 |
| DIEXF | digestive organ expansion factor homolog (zebrafish) |
| EGR1 | early growth response 1 |
| EGR3 | early growth response 3 |
| ELL | elongation factor RNA polymerase II |
| EPS8L2 | EPS8-like 2 |
| FAS | Fas cell surface death receptor |
| FBXL8 | F-box and leucine-rich repeat protein 8 |
| FOSL1 | FOS-like antigen 1 |
| FRZB | frizzled-related protein |
| GABBR2 | gamma-aminobutyric acid (GABA) B receptor, 2 |
| GLS | glutaminase |
| GPR87 | G protein-coupled receptor 87 |
| GSK3A | glycogen synthase kinase 3 alpha |
| GSTTP1 | glutathione S-transferase theta pseudogene 1 |
| HBS1L | HBS1-like translational GTPase |
| HIST1H3B | histone cluster 1, H3b |
| HOXD1 | homeobox D1 |
| HPN | hepsin |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| KRT15 | keratin 15, type I |
| LIF | leukemia inhibitory factor |
| LOC157562 | uncharacterized LOC157562 |
| LRRC14 | leucine rich repeat containing 14 |
| LRRC17 | leucine rich repeat containing 17 |
| LTB4R | leukotriene B4 receptor |
| LTBP2 | latent transforming growth factor beta binding protein 2 |
| MAP4 | microtubule-associated protein 4 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| MERTK | MER proto-oncogene, tyrosine kinase |
| MGAM | maltase-glucoamylase |
| MIEF1 | mitochondrial elongation factor 1 |
| MINOS1P1 | mitochondrial inner membrane organizing system 1 pseudogene 1 |
| MTL5 | metallothionein-like 5, testis-specific (tesmin) |
| N4BP2L2 | NEDD4 binding protein 2-like 2 |
| NBL1 | neuroblastoma 1, DAN family BMP antagonist |
| NGDN | neuroguidin, EIF4E binding protein |
| NOV | nephroblastoma overexpressed |
| NPR3 | natriuretic peptide receptor 3 |
| NRF1 | nuclear respiratory factor 1 |
| PAQR6 | progestin and adipoQ receptor family member VI |
| PARVB | parvin, beta |
| PIDD1 | p53-induced death domain protein 1 |
| PLCD1 | phospholipase C, delta 1 |
| PNPLA6 | patatin-like phospholipase domain containing 6 |
| POU2F2 | POU class 2 homeobox 2 |
| RBM14 | RNA binding motif protein 14 |
| RGS5 | regulator of G-protein signaling 5 |
| RSL1D1 | ribosomal L1 domain containing 1 |
| RYR2 | ryanodine receptor 2 (cardiac) |
| SCAND2P | SCAN domain containing 2 pseudogene |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B |
| SESN1 | sestrin 1 |
| SGSH | N-sulfoglucosamine sulfohydrolase |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 |
| SLC35E2 | solute carrier family 35, member E2 |
| SMIM7 | small integral membrane protein 7 |
| SRGAP3 | SLIT-ROBO Rho GTPase activating protein 3 |
| SUGP1 | SURP and G patch domain containing 1 |
| SYMPK | symplekin |
| TMEM120B | transmembrane protein 120B |
| TMEM63A | transmembrane protein 63A |
| TRIM66 | tripartite motif containing 66 |
| UBOX5 | U-box domain containing 5 |
| UCN | urocortin |
| UGT2B28 | UDP glucuronosyltransferase 2 family, polypeptide B28 |
| UPK3A | uroplakin 3A |
| UTP14A | UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast) |
| VAMP5 | vesicle-associated membrane protein 5 |
| VIPR2 | vasoactive intestinal peptide receptor 2 |
| WDR1 | WD repeat domain 1 |
| ZBTB1 | zinc finger and BTB domain containing 1 |
| ZFP2 | ZFP2 zinc finger protein |
| ZMAT3 | zinc finger, matrin-type 3 |
| ZNF862 | zinc finger protein 862 |
| ZRSR1 | zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 1 |
| Symbol | Name |
|---|---|
| ABHD3 | abhydrolase domain containing 3 |
| ADORA2B | adenosine A2b receptor |
| AMIGO2 | adhesion molecule with Ig-like domain 2 |
| ANKFY1 | ankyrin repeat and FYVE domain containing 1 |
| AP5S1 | adaptor-related protein complex 5, sigma 1 subunit |
| ARHGAP5 | Rho GTPase activating protein 5 |
| ARMCX5 | armadillo repeat containing, X-linked 5 |
| ARRB1 | arrestin, beta 1 |
| ATAD2B | ATPase family, AAA domain containing 2B |
| ATP11B | ATPase, class VI, type 11B |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide |
| BBS7 | Bardet-Biedl syndrome 7 |
| BIK | BCL2-interacting killer (apoptosis-inducing) |
| C9ORF3 | chromosome 9 open reading frame 3 |
| CBR3 | carbonyl reductase 3 |
| CCNE2 | cyclin E2 |
| CDC73 | cell division cycle 73 |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha |
| CENPJ | centromere protein J |
| CHORDC1 | cysteine and histidine-rich domain (CHORD) containing 1 |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| DENND1B | DENN/MADD domain containing 1B |
| DNAJC22 | DnaJ (Hsp40) homolog, subfamily C, member 22 |
| DNAJC24 | DnaJ (Hsp40) homolog, subfamily C, member 24 |
| DNMT3B | DNA (cytosine-5-)-methyltransferase 3 beta |
| DTWD1 | DTW domain containing 1 |
| E2F8 | E2F transcription factor 8 |
| EAF2 | ELL associated factor 2 |
| EPHA4 | EPH receptor A4 |
| FLVCR2 | feline leukemia virus subgroup C cellular receptor family, member 2 |
| FOXD1 | forkhead box D1 |
| GABPA | GA binding protein transcription factor, alpha subunit 60kDa |
| GCH1 | GTP cyclohydrolase 1 |
| GLI3 | GLI family zinc finger 3 |
| GNA12 | guanine nucleotide binding protein (G protein) alpha 12 |
| GNE | glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase |
| GPRC5C | G protein-coupled receptor, class C, group 5, member C |
| GTF2I | general transcription factor IIi |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 |
| HSPA2 | heat shock 70kDa protein 2 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
| INPP5A | inositol polyphosphate-5-phosphatase, 40kDa |
| KCNS3 | potassium voltage-gated channel, modifier subfamily S, member 3 |
| KIF11 | kinesin family member 11 |
| KIF16B | kinesin family member 16B |
| KLF11 | Kruppel-like factor 11 |
| KRBOX4 | KRAB box domain containing 4 |
| LINC00115 | long intergenic non-protein coding RNA 115 |
| LMNB1 | lamin B1 |
| LOC730101 | uncharacterized LOC730101 |
| LRRC16A | leucine rich repeat containing 16A |
| MAD1L1 | MAD1 mitotic arrest deficient-like 1 (yeast) |
| MEPCE | methylphosphate capping enzyme |
| MSL1 | male-specific lethal 1 homolog (Drosophila) |
| MSX1 | msh homeobox 1 |
| MTCL1 | microtubule crosslinking factor 1 |
| MTHFS | 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase) |
| MTR | 5-methyltetrahydrofolate-homocysteine methyltransferase |
| MYD88 | myeloid differentiation primary response 88 |
| NDC80 | NDC80 kinetochore complex component |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase |
| NUDT13 | nudix (nucleoside diphosphate linked moiety X)-type motif 13 |
| PAGR1 | PAXIP1 associated glutamate-rich protein 1 |
| PAQR3 | progestin and adipoQ receptor family member III |
| PDP1 | pyruvate dehyrogenase phosphatase catalytic subunit 1 |
| PDZRN3 | PDZ domain containing ring finger 3 |
| PHACTR4 | phosphatase and actin regulator 4 |
| PIP5K1C | phosphatidylinositol-4-phosphate 5-kinase, type I, gamma |
| PLEKHO1 | pleckstrin homology domain containing, family O member 1 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit |
| PPWD1 | peptidylprolyl isomerase domain and WD repeat containing 1 |
| PRR3 | proline rich 3 |
| RGS19 | regulator of G-protein signaling 19 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 |
| SEH1L | SEH1-like (S. cerevisiae) |
| SLC35A5 | solute carrier family 35, member A5 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 |
| SMAGP | small cell adhesion glycoprotein |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| SMG9 | SMG9 nonsense mediated mRNA decay factor |
| SPC25 | SPC25, NDC80 kinetochore complex component |
| SPHK1 | sphingosine kinase 1 |
| STXBP3 | syntaxin binding protein 3 |
| TPST1 | tyrosylprotein sulfotransferase 1 |
| TRAF5 | TNF receptor-associated factor 5 |
| TRMT11 | tRNA methyltransferase 11 homolog (S. cerevisiae) |
| TTC17 | tetratricopeptide repeat domain 17 |
| TXLNG | taxilin gamma |
| VAV1 | vav 1 guanine nucleotide exchange factor |
| VAV3 | vav 3 guanine nucleotide exchange factor |
| WDR4 | WD repeat domain 4 |
| YARS2 | tyrosyl-tRNA synthetase 2, mitochondrial |
| ZCCHC10 | zinc finger, CCHC domain containing 10 |
| ZCCHC2 | zinc finger, CCHC domain containing 2 |
| ZIC1 | Zic family member 1 |
| ZNF33B | zinc finger protein 33B |
| ZNF573 | zinc finger protein 573 |
| ZNF586 | zinc finger protein 586 |
| ZNF652 | zinc finger protein 652 |