apigenin-3257 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the apigenin-3257 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACTA2 actin, alpha 2, smooth muscle, aorta
AEN apoptosis enhancing nuclease
AIM2 absent in melanoma 2
ALDH3B1 aldehyde dehydrogenase 3 family, member B1
ALDH8A1 aldehyde dehydrogenase 8 family, member A1
APOLD1 apolipoprotein L domain containing 1
BAIAP3 BAI1-associated protein 3
BBS1 Bardet-Biedl syndrome 1
BMP15 bone morphogenetic protein 15
C11ORF1 chromosome 11 open reading frame 1
C11ORF63 chromosome 11 open reading frame 63
C14ORF79 chromosome 14 open reading frame 79
CATSPERB catsper channel auxiliary subunit beta
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2
CCDC71 coiled-coil domain containing 71
CCDC88C coiled-coil domain containing 88C
CCNT2 cyclin T2
CD59 CD59 molecule, complement regulatory protein
CD82 CD82 molecule
CDKL3 cyclin-dependent kinase-like 3
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CEL carboxyl ester lipase
CRY2 cryptochrome circadian clock 2
CSTF3 cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1
DIEXF digestive organ expansion factor homolog (zebrafish)
EGR1 early growth response 1
EGR3 early growth response 3
ELL elongation factor RNA polymerase II
EPS8L2 EPS8-like 2
FAS Fas cell surface death receptor
FBXL8 F-box and leucine-rich repeat protein 8
FOSL1 FOS-like antigen 1
FRZB frizzled-related protein
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GLS glutaminase
GPR87 G protein-coupled receptor 87
GSK3A glycogen synthase kinase 3 alpha
GSTTP1 glutathione S-transferase theta pseudogene 1
HBS1L HBS1-like translational GTPase
HIST1H3B histone cluster 1, H3b
HOXD1 homeobox D1
HPN hepsin
IDI2-AS1 IDI2 antisense RNA 1
KRT15 keratin 15, type I
LIF leukemia inhibitory factor
LOC157562 uncharacterized LOC157562
LRRC14 leucine rich repeat containing 14
LRRC17 leucine rich repeat containing 17
LTB4R leukotriene B4 receptor
LTBP2 latent transforming growth factor beta binding protein 2
MAP4 microtubule-associated protein 4
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MERTK MER proto-oncogene, tyrosine kinase
MGAM maltase-glucoamylase
MIEF1 mitochondrial elongation factor 1
MINOS1P1 mitochondrial inner membrane organizing system 1 pseudogene 1
MTL5 metallothionein-like 5, testis-specific (tesmin)
N4BP2L2 NEDD4 binding protein 2-like 2
NBL1 neuroblastoma 1, DAN family BMP antagonist
NGDN neuroguidin, EIF4E binding protein
NOV nephroblastoma overexpressed
NPR3 natriuretic peptide receptor 3
NRF1 nuclear respiratory factor 1
PAQR6 progestin and adipoQ receptor family member VI
PARVB parvin, beta
PIDD1 p53-induced death domain protein 1
PLCD1 phospholipase C, delta 1
PNPLA6 patatin-like phospholipase domain containing 6
POU2F2 POU class 2 homeobox 2
RBM14 RNA binding motif protein 14
RGS5 regulator of G-protein signaling 5
RSL1D1 ribosomal L1 domain containing 1
RYR2 ryanodine receptor 2 (cardiac)
SCAND2P SCAN domain containing 2 pseudogene
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
SESN1 sestrin 1
SGSH N-sulfoglucosamine sulfohydrolase
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC35E2 solute carrier family 35, member E2
SMIM7 small integral membrane protein 7
SRGAP3 SLIT-ROBO Rho GTPase activating protein 3
SUGP1 SURP and G patch domain containing 1
SYMPK symplekin
TMEM120B transmembrane protein 120B
TMEM63A transmembrane protein 63A
TRIM66 tripartite motif containing 66
UBOX5 U-box domain containing 5
UCN urocortin
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28
UPK3A uroplakin 3A
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)
VAMP5 vesicle-associated membrane protein 5
VIPR2 vasoactive intestinal peptide receptor 2
WDR1 WD repeat domain 1
ZBTB1 zinc finger and BTB domain containing 1
ZFP2 ZFP2 zinc finger protein
ZMAT3 zinc finger, matrin-type 3
ZNF862 zinc finger protein 862
ZRSR1 zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 1

decreased expression

Symbol Name
ABHD3 abhydrolase domain containing 3
ADORA2B adenosine A2b receptor
AMIGO2 adhesion molecule with Ig-like domain 2
ANKFY1 ankyrin repeat and FYVE domain containing 1
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
ARHGAP5 Rho GTPase activating protein 5
ARMCX5 armadillo repeat containing, X-linked 5
ARRB1 arrestin, beta 1
ATAD2B ATPase family, AAA domain containing 2B
ATP11B ATPase, class VI, type 11B
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
BBS7 Bardet-Biedl syndrome 7
BIK BCL2-interacting killer (apoptosis-inducing)
C9ORF3 chromosome 9 open reading frame 3
CBR3 carbonyl reductase 3
CCNE2 cyclin E2
CDC73 cell division cycle 73
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CENPJ centromere protein J
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
DENND1B DENN/MADD domain containing 1B
DNAJC22 DnaJ (Hsp40) homolog, subfamily C, member 22
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
DTWD1 DTW domain containing 1
E2F8 E2F transcription factor 8
EAF2 ELL associated factor 2
EPHA4 EPH receptor A4
FLVCR2 feline leukemia virus subgroup C cellular receptor family, member 2
FOXD1 forkhead box D1
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GCH1 GTP cyclohydrolase 1
GLI3 GLI family zinc finger 3
GNA12 guanine nucleotide binding protein (G protein) alpha 12
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
GPRC5C G protein-coupled receptor, class C, group 5, member C
GTF2I general transcription factor IIi
HIVEP1 human immunodeficiency virus type I enhancer binding protein 1
HSPA2 heat shock 70kDa protein 2
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
INPP5A inositol polyphosphate-5-phosphatase, 40kDa
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3
KIF11 kinesin family member 11
KIF16B kinesin family member 16B
KLF11 Kruppel-like factor 11
KRBOX4 KRAB box domain containing 4
LINC00115 long intergenic non-protein coding RNA 115
LMNB1 lamin B1
LOC730101 uncharacterized LOC730101
LRRC16A leucine rich repeat containing 16A
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast)
MEPCE methylphosphate capping enzyme
MSL1 male-specific lethal 1 homolog (Drosophila)
MSX1 msh homeobox 1
MTCL1 microtubule crosslinking factor 1
MTHFS 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase
MYD88 myeloid differentiation primary response 88
NDC80 NDC80 kinetochore complex component
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
NUDT13 nudix (nucleoside diphosphate linked moiety X)-type motif 13
PAGR1 PAXIP1 associated glutamate-rich protein 1
PAQR3 progestin and adipoQ receptor family member III
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1
PDZRN3 PDZ domain containing ring finger 3
PHACTR4 phosphatase and actin regulator 4
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
PLEKHO1 pleckstrin homology domain containing, family O member 1
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
PPWD1 peptidylprolyl isomerase domain and WD repeat containing 1
PRR3 proline rich 3
RGS19 regulator of G-protein signaling 19
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3
SEH1L SEH1-like (S. cerevisiae)
SLC35A5 solute carrier family 35, member A5
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SMAGP small cell adhesion glycoprotein
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SMG9 SMG9 nonsense mediated mRNA decay factor
SPC25 SPC25, NDC80 kinetochore complex component
SPHK1 sphingosine kinase 1
STXBP3 syntaxin binding protein 3
TPST1 tyrosylprotein sulfotransferase 1
TRAF5 TNF receptor-associated factor 5
TRMT11 tRNA methyltransferase 11 homolog (S. cerevisiae)
TTC17 tetratricopeptide repeat domain 17
TXLNG taxilin gamma
VAV1 vav 1 guanine nucleotide exchange factor
VAV3 vav 3 guanine nucleotide exchange factor
WDR4 WD repeat domain 4
YARS2 tyrosyl-tRNA synthetase 2, mitochondrial
ZCCHC10 zinc finger, CCHC domain containing 10
ZCCHC2 zinc finger, CCHC domain containing 2
ZIC1 Zic family member 1
ZNF33B zinc finger protein 33B
ZNF573 zinc finger protein 573
ZNF586 zinc finger protein 586
ZNF652 zinc finger protein 652