| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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198 genes differentially expressed following the apigenin-4578 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCF2 | ATP-binding cassette, sub-family F (GCN20), member 2 |
| ALOX5 | arachidonate 5-lipoxygenase |
| ALPPL2 | alkaline phosphatase, placental-like 2 |
| AOC3 | amine oxidase, copper containing 3 |
| ARHGAP28 | Rho GTPase activating protein 28 |
| ATXN7L1 | ataxin 7-like 1 |
| C11ORF1 | chromosome 11 open reading frame 1 |
| C11ORF63 | chromosome 11 open reading frame 63 |
| C14ORF105 | chromosome 14 open reading frame 105 |
| C1QTNF3 | C1q and tumor necrosis factor related protein 3 |
| C2CD2L | C2CD2-like |
| CABP2 | calcium binding protein 2 |
| CADM3 | cell adhesion molecule 3 |
| CALML3 | calmodulin-like 3 |
| CCDC186 | coiled-coil domain containing 186 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 |
| CELP | carboxyl ester lipase pseudogene |
| CLCN7 | chloride channel, voltage-sensitive 7 |
| CLUL1 | clusterin-like 1 (retinal) |
| CST4 | cystatin S |
| CSTF3 | cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa |
| CTAG2 | cancer/testis antigen 2 |
| CTNND2 | catenin (cadherin-associated protein), delta 2 |
| CXORF21 | chromosome X open reading frame 21 |
| DEFB4A | defensin, beta 4A |
| DMP1 | dentin matrix acidic phosphoprotein 1 |
| DNAAF1 | dynein, axonemal, assembly factor 1 |
| DTNB | dystrobrevin, beta |
| EPYC | epiphycan |
| EYA3 | EYA transcriptional coactivator and phosphatase 3 |
| FGFR4 | fibroblast growth factor receptor 4 |
| FILIP1L | filamin A interacting protein 1-like |
| FLT4 | fms-related tyrosine kinase 4 |
| GAS7 | growth arrest-specific 7 |
| HAP1 | huntingtin-associated protein 1 |
| HBS1L | HBS1-like translational GTPase |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) |
| HPCA | hippocalcin |
| HS6ST1 | heparan sulfate 6-O-sulfotransferase 1 |
| HTR1B | 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled |
| HTR7P1 | 5-hydroxytryptamine (serotonin) receptor 7 pseudogene 1 |
| HYAL1 | hyaluronoglucosaminidase 1 |
| IGHA1 | immunoglobulin heavy constant alpha 1 |
| IL1RN | interleukin 1 receptor antagonist |
| KCNAB1 | potassium channel, voltage gated subfamily A regulatory beta subunit 1 |
| KIAA1045 | KIAA1045 |
| KRT7 | keratin 7, type II |
| LEFTY1 | left-right determination factor 1 |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| LOC157562 | uncharacterized LOC157562 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| MTMR3 | myotubularin related protein 3 |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
| N4BP2L1 | NEDD4 binding protein 2-like 1 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 |
| NDUFB7 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa |
| NEK9 | NIMA-related kinase 9 |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
| NOTCH3 | notch 3 |
| NUP88 | nucleoporin 88kDa |
| PAQR6 | progestin and adipoQ receptor family member VI |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide |
| PLEKHG3 | pleckstrin homology domain containing, family G (with RhoGef domain) member 3 |
| POPDC2 | popeye domain containing 2 |
| POU6F2 | POU class 6 homeobox 2 |
| PRDM14 | PR domain containing 14 |
| PRM2 | protamine 2 |
| PROL1 | proline rich, lacrimal 1 |
| PRX | periaxin |
| PTGER3 | prostaglandin E receptor 3 (subtype EP3) |
| RAB6A | RAB6A, member RAS oncogene family |
| RAPGEFL1 | Rap guanine nucleotide exchange factor (GEF)-like 1 |
| RGS5 | regulator of G-protein signaling 5 |
| SCN10A | sodium channel, voltage gated, type X alpha subunit |
| SELL | selectin L |
| SEMA3D | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D |
| SFI1 | Sfi1 homolog, spindle assembly associated (yeast) |
| SGCD | sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) |
| SHANK1 | SH3 and multiple ankyrin repeat domains 1 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 |
| SLC1A7 | solute carrier family 1 (glutamate transporter), member 7 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 |
| SLC30A5 | solute carrier family 30 (zinc transporter), member 5 |
| SLCO2A1 | solute carrier organic anion transporter family, member 2A1 |
| SOX30 | SRY (sex determining region Y)-box 30 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 |
| SUPT20H | suppressor of Ty 20 homolog (S. cerevisiae) |
| TAAR5 | trace amine associated receptor 5 |
| TCL6 | T-cell leukemia/lymphoma 6 (non-protein coding) |
| TCP10L | t-complex 10-like |
| TEF | thyrotrophic embryonic factor |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 |
| TRIO | trio Rho guanine nucleotide exchange factor |
| UBA7 | ubiquitin-like modifier activating enzyme 7 |
| WDR59 | WD repeat domain 59 |
| ZNF268 | zinc finger protein 268 |
| ZNF44 | zinc finger protein 44 |
| ZNF639 | zinc finger protein 639 |
| ZRSR1 | zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 1 |
| Symbol | Name |
|---|---|
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 |
| ANKFY1 | ankyrin repeat and FYVE domain containing 1 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) |
| ARMCX5 | armadillo repeat containing, X-linked 5 |
| AZI2 | 5-azacytidine induced 2 |
| BBS7 | Bardet-Biedl syndrome 7 |
| C1ORF115 | chromosome 1 open reading frame 115 |
| C1ORF27 | chromosome 1 open reading frame 27 |
| C1QTNF1 | C1q and tumor necrosis factor related protein 1 |
| C9ORF91 | chromosome 9 open reading frame 91 |
| CD83 | CD83 molecule |
| CDC37L1 | cell division cycle 37-like 1 |
| CHMP7 | charged multivesicular body protein 7 |
| CLASP1 | cytoplasmic linker associated protein 1 |
| CRYBB2P1 | crystallin, beta B2 pseudogene 1 |
| CTAGE9 | CTAGE family, member 9 |
| CUTC | cutC copper transporter |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) |
| DAAM1 | dishevelled associated activator of morphogenesis 1 |
| DCAF16 | DDB1 and CUL4 associated factor 16 |
| EFNA3 | ephrin-A3 |
| EOGT | EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase |
| ERCC2 | excision repair cross-complementation group 2 |
| FSTL3 | follistatin-like 3 (secreted glycoprotein) |
| GCH1 | GTP cyclohydrolase 1 |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| GJC1 | gap junction protein, gamma 1, 45kDa |
| GPR87 | G protein-coupled receptor 87 |
| GRAMD3 | GRAM domain containing 3 |
| HLX | H2.0-like homeobox |
| HPSE | heparanase |
| IFT46 | intraflagellar transport 46 |
| IL1B | interleukin 1, beta |
| ING3 | inhibitor of growth family, member 3 |
| ISOC1 | isochorismatase domain containing 1 |
| JMJD4 | jumonji domain containing 4 |
| KCTD7 | potassium channel tetramerization domain containing 7 |
| KIF15 | kinesin family member 15 |
| LOC730101 | uncharacterized LOC730101 |
| LPAR6 | lysophosphatidic acid receptor 6 |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MEIS1 | Meis homeobox 1 |
| MEPCE | methylphosphate capping enzyme |
| MITF | microphthalmia-associated transcription factor |
| MSL1 | male-specific lethal 1 homolog (Drosophila) |
| MTMR11 | myotubularin related protein 11 |
| NDRG4 | NDRG family member 4 |
| NDUFAF1 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 1 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase |
| NR3C2 | nuclear receptor subfamily 3, group C, member 2 |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
| PALMD | palmdelphin |
| PARP16 | poly (ADP-ribose) polymerase family, member 16 |
| PDZD2 | PDZ domain containing 2 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 |
| PIAS3 | protein inhibitor of activated STAT, 3 |
| PLK2 | polo-like kinase 2 |
| POLA2 | polymerase (DNA directed), alpha 2, accessory subunit |
| POLR3D | polymerase (RNA) III (DNA directed) polypeptide D, 44kDa |
| PPM1H | protein phosphatase, Mg2+/Mn2+ dependent, 1H |
| PTX3 | pentraxin 3, long |
| RASSF2 | Ras association (RalGDS/AF-6) domain family member 2 |
| RBL1 | retinoblastoma-like 1 |
| RBM38 | RNA binding motif protein 38 |
| RGL1 | ral guanine nucleotide dissociation stimulator-like 1 |
| RHOBTB1 | Rho-related BTB domain containing 1 |
| RPGR | retinitis pigmentosa GTPase regulator |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| SEC61A2 | Sec61 alpha 2 subunit (S. cerevisiae) |
| SERPINB8 | serpin peptidase inhibitor, clade B (ovalbumin), member 8 |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SGMS1 | sphingomyelin synthase 1 |
| SLC17A5 | solute carrier family 17 (acidic sugar transporter), member 5 |
| SLC35A1 | solute carrier family 35 (CMP-sialic acid transporter), member A1 |
| SLC35A5 | solute carrier family 35, member A5 |
| SLC46A3 | solute carrier family 46, member 3 |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| SMPDL3A | sphingomyelin phosphodiesterase, acid-like 3A |
| SPC25 | SPC25, NDC80 kinetochore complex component |
| ST5 | suppression of tumorigenicity 5 |
| STAC | SH3 and cysteine rich domain |
| TARS2 | threonyl-tRNA synthetase 2, mitochondrial (putative) |
| TBC1D19 | TBC1 domain family, member 19 |
| TBX3 | T-box 3 |
| TMEM2 | transmembrane protein 2 |
| TNFRSF11A | tumor necrosis factor receptor superfamily, member 11a, NFKB activator |
| TNKS2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 |
| TSPAN12 | tetraspanin 12 |
| TTC17 | tetratricopeptide repeat domain 17 |
| TTLL7 | tubulin tyrosine ligase-like family member 7 |
| TUBA3C | tubulin, alpha 3c |
| ZBTB10 | zinc finger and BTB domain containing 10 |
| ZNF165 | zinc finger protein 165 |
| ZNF248 | zinc finger protein 248 |
| ZNF33B | zinc finger protein 33B |
| ZNF365 | zinc finger protein 365 |
| ZNF408 | zinc finger protein 408 |
| ZNF552 | zinc finger protein 552 |
| ZNF586 | zinc finger protein 586 |