apnea Gene Set

Dataset	MPO Gene-Phenotype Associations
Category	disease or phenotype associations
Type	phenotype
Description	Lack of breathing with no movement of the respiratory muscles and no exchange of air in the lungs. This term refers to a disposition to have recurrent episodes of apnea rather than to a single event. (Human Phenotype Ontology, HP_0002104)
External Link	http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0001957
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Genes

20 gene mutations causing the apnea phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol	Name
ADK	adenosine kinase
ALPL	alkaline phosphatase, liver/bone/kidney
CHRNB2	cholinergic receptor, nicotinic, beta 2 (neuronal)
DHCR7	7-dehydrocholesterol reductase
DSCAM	Down syndrome cell adhesion molecule
GPHN	gephyrin
GRIN1	glutamate receptor, ionotropic, N-methyl D-aspartate 1
GSX2	GS homeobox 2
KCNA2	potassium channel, voltage gated shaker related subfamily A, member 2
KCNN3	potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 3
MAFB	v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MECP2	methyl CpG binding protein 2
NALCN	sodium leak channel, non selective
NDUFS4	NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase)
PHOX2B	paired-like homeobox 2b
SCN10A	sodium channel, voltage gated, type X alpha subunit
SIX1	SIX homeobox 1
SLC5A3	solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
SLC6A9	solute carrier family 6 (neurotransmitter transporter, glycine), member 9
TLX3	T-cell leukemia homeobox 3