apoptosome Gene Set

Dataset COMPARTMENTS Curated Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A multisubunit protein complex involved in the signaling phase of the apoptotic process. In mammals it is typically composed of seven Apaf-1 subunits bound to cytochrome c and caspase-9. A similar complex to promote apoptosis is formed from homologous gene products in other eukaryotic organisms. (Gene Ontology, GO_0043293)
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3 proteins localized to the apoptosome cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
APAF1 apoptotic peptidase activating factor 1 0.663342
CASP9 caspase 9, apoptosis-related cysteine peptidase 0.663342
UACA uveal autoantigen with coiled-coil domains and ankyrin repeats 0.03318