apoptosome Gene Set

Dataset GO Cellular Component Annotations 2015
Category structural or functional annotations
Type cellular component
Description A multisubunit protein complex involved in the signaling phase of the apoptotic process. In mammals it is typically composed of seven Apaf-1 subunits bound to cytochrome c and caspase-9. A similar complex to promote apoptosis is formed from homologous gene products in other eukaryotic organisms. (Gene Ontology, GO_0043293)
External Link http://amigo.geneontology.org/amigo/term/GO:0043293
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Genes

3 proteins localized to the apoptosome cellular component from the curated GO Cellular Component Annotations 2015 dataset.

Symbol Name
APAF1 apoptotic peptidase activating factor 1
CASP9 caspase 9, apoptosis-related cysteine peptidase
UACA uveal autoantigen with coiled-coil domains and ankyrin repeats