apoptosome Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description A multisubunit protein complex involved in the signaling phase of the apoptotic process. In mammals it is typically composed of seven Apaf-1 subunits bound to cytochrome c and caspase-9. A similar complex to promote apoptosis is formed from homologous gene products in other eukaryotic organisms. (Gene Ontology, GO_0043293)
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Genes

23 genes co-occuring with the biological term apoptosome in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ACHE acetylcholinesterase (Yt blood group)
AFP alpha-fetoprotein
APAF1 apoptotic peptidase activating factor 1
APIP APAF1 interacting protein
BIRC2 baculoviral IAP repeat containing 2
CARD9 caspase recruitment domain family, member 9
CASP2 caspase 2, apoptosis-related cysteine peptidase
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP9 caspase 9, apoptosis-related cysteine peptidase
CAV1 caveolin 1, caveolae protein, 22kDa
CYCS cytochrome c, somatic
DIABLO diablo, IAP-binding mitochondrial protein
EIF3M eukaryotic translation initiation factor 3, subunit M
GPI glucose-6-phosphate isomerase
HIP1 huntingtin interacting protein 1
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
HSPB1 heat shock 27kDa protein 1
MTCH1 mitochondrial carrier 1
PRKCD protein kinase C, delta
TP53 tumor protein p53
TPPP tubulin polymerization promoting protein
UACA uveal autoantigen with coiled-coil domains and ankyrin repeats
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase