appendicitis Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description A gastrointestinal system infectious disease that involves inflammation and infection of the appendix caused by the blockage of the lumen with a small, hard piece of stool, a foreign body or worms. Mucus backs up in the appendiceal lumen, causing bacteria that live inside the appendix to multiply. The infection has_symptom pain, in the upper abdomen initially and later in the lower abdomen, has_symptom nausea, has_symptom vomiting and has_symptom fever. (Human Disease Ontology, DOID_8337)
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Genes

12 genes co-occuring with the biological term appendicitis in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
CD19 CD19 molecule
EDN1 endothelin 1
HTOR 5-hydroxytryptamine (serotonin) oxygenase regulator
IL6 interleukin 6
LEPR leptin receptor
MMP9 matrix metallopeptidase 9
NOD2 nucleotide-binding oligomerization domain containing 2
SELE selectin E
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
TIMP1 TIMP metallopeptidase inhibitor 1
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
VCAM1 vascular cell adhesion molecule 1